5AE4

Structures of inactive and activated DntR provide conclusive evidence for the mechanism of action of LysR transcription factors

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	LYSR-TYPE REGULATORY PROTEIN	polymer	308	34835.2	2	UniProt (Q7WT50) Pfam (PF00126) Pfam (PF03466)	BURKHOLDERIA CEPACIA	DNTR
2	C, D (A, B)	THIOCYANATE ION	non-polymer		58.1	2	Chemie (SCN)

Sequence modifications

A, B: 1 - 301 (UniProt: Q7WT50)

PDB	External Database	Details
Arg 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag
Thr 169	His 169	engineered mutation
Ser 192	Thr 192	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	69670.5
Non-Polymers*	Number of molecules	2
	Total formula weight	116.2
All*	Total formula weight	69786.6

*Water molecules are not included.