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5F0S
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BU of 5f0s by Molmil
Crystal structure of C-terminal domain of the human DNA primase large subunit with bound DNA template/RNA primer and manganese ion
Descriptor: DNA (5'-D(*GP*CP*CP*GP*CP*CP*AP*AP*CP*AP*TP*A)-3'), DNA primase large subunit, IRON/SULFUR CLUSTER, ...
Authors:Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D.
Deposit date:2015-11-28
Release date:2016-03-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome.
J.Biol.Chem., 291, 2016
2UUA
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BU of 2uua by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUC-codon in the A-site and paromomycin.
Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V.
Deposit date:2007-03-01
Release date:2007-05-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines.
Nat. Struct. Mol. Biol., 14, 2007
6SO9
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BU of 6so9 by Molmil
Mouse RBM20 RRM domain in complex with AUCUUA RNA
Descriptor: AUCUUA, RNA-binding protein 20
Authors:Mackereth, C.D, Upadhyay, S.K.
Deposit date:2019-08-29
Release date:2019-11-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis of UCUU RNA motif recognition by splicing factor RBM20.
Nucleic Acids Res., 48, 2020
7OGJ
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BU of 7ogj by Molmil
Crystal structure of human METTL1 in complex with SAH
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Nai, F, Bedi, R.K, Caflisch, A.
Deposit date:2021-05-06
Release date:2021-05-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Small-Molecule Inhibitors of the m7G-RNA Writer METTL1
Acs Bio Med Chem Au, 2023
5NKK
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BU of 5nkk by Molmil
SMG8-SMG9 complex GDP bound
Descriptor: 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Li, L, Basquin, J, Conti, E.
Deposit date:2017-03-31
Release date:2017-04-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structure of a SMG8-SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins.
RNA, 23, 2017
5BJR
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BU of 5bjr by Molmil
Crystal structure of the N-terminal RRM domain from MEC-8
Descriptor: AMMONIUM ION, Mec-8 protein
Authors:Soufari, H, Mackereth, C.D.
Deposit date:2016-10-22
Release date:2017-01-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Conserved binding of GCAC motifs by MEC-8, couch potato, and the RBPMS protein family.
RNA, 23, 2017
5F0Q
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BU of 5f0q by Molmil
Crystal structure of C-terminal domain of the human DNA primase large subunit with bound DNA template/RNA primer
Descriptor: DNA (5'-D(*GP*CP*CP*GP*CP*CP*AP*AP*CP*AP*TP*A)-3'), DNA primase large subunit, IRON/SULFUR CLUSTER, ...
Authors:Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D.
Deposit date:2015-11-28
Release date:2016-03-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome.
J.Biol.Chem., 291, 2016
7OHU
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BU of 7ohu by Molmil
Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL2 expression shut down, population B
Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-03
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
7OHY
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BU of 7ohy by Molmil
Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL34 expression shut down, population B
Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-03
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
1MWL
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BU of 1mwl by Molmil
Crystal structure of geneticin bound to the eubacterial 16S rRNA A site
Descriptor: 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', GENETICIN
Authors:Vicens, Q, Westhof, E.
Deposit date:2002-09-30
Release date:2003-02-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of geneticin bound to a bacterial 16S ribosomal RNA A site oligonucleotide
J.Mol.Biol., 326, 2003
3J7O
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BU of 3j7o by Molmil
Structure of the mammalian 60S ribosomal subunit
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
2KI7
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BU of 2ki7 by Molmil
The solution structure of RPP29-RPP21 complex from Pyrococcus furiosus
Descriptor: Ribonuclease P protein component 1, Ribonuclease P protein component 4, ZINC ION
Authors:Xu, Y, Foster, M.P.
Deposit date:2009-04-28
Release date:2009-09-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of an archaeal RNase P binary protein complex: formation of the 30-kDa complex between Pyrococcus furiosus RPP21 and RPP29 is accompanied by coupled protein folding and highlights critical features for protein-protein and protein-RNA interactions.
J.Mol.Biol., 393, 2009
4H4L
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BU of 4h4l by Molmil
Crystal Structure of ternary complex of HutP(HutP-L-His-Zn)
Descriptor: HISTIDINE, Hut operon positive regulatory protein, ZINC ION
Authors:Dhakshnamoorthy, B, Misono, T.S, Mizuno, H, Kumar, P.K.R.
Deposit date:2012-09-17
Release date:2013-09-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Alternative binding modes of l-histidine guided by metal ions for the activation of the antiterminator protein HutP of Bacillus subtilis.
J.Struct.Biol., 183, 2013
5A0V
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BU of 5a0v by Molmil
Catalysis and 5' end sensing by ribonuclease RNase J of the metallo- beta-lactamase family
Descriptor: 5'-R(*CP*GP*CP*CP*UP*CP)-3', CYTIDINE-5'-MONOPHOSPHATE, RIBONUCLEASE J, ...
Authors:Pei, X.Y, Bralley, P, Jones, G.H, Luisi, B.F.
Deposit date:2015-04-23
Release date:2015-08-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Linkage of Catalysis and 5' End Recognition in Ribonuclease Rnase J
Nucleic Acids Res., 43, 2015
5A0T
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BU of 5a0t by Molmil
Catalysis and 5' end sensing by ribonuclease RNase J of the metallo- beta-lactamase family
Descriptor: 5'-R(*CP*GP*CP*CP*UP)-3', DI(HYDROXYETHYL)ETHER, RIBONUCLEASE J, ...
Authors:Pei, X.Y, Bralley, P, Jones, G.H, Luisi, B.F.
Deposit date:2015-04-22
Release date:2015-08-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.283 Å)
Cite:Linkage of Catalysis and 5' End Recognition in Ribonuclease Rnase J
Nucleic Acids Res., 43, 2015
4ZLD
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BU of 4zld by Molmil
Crystal structure of human Roquin-2 ROQ domain in complex with Roquin CDE RNA
Descriptor: GLYCEROL, RNA (5'-R(*UP*AP*AP*CP*UP*UP*CP*UP*GP*UP*GP*AP*AP*GP*UP*UP*G)-3'), Roquin-2
Authors:Sakurai, S, Ohto, U, Shimizu, T.
Deposit date:2015-05-01
Release date:2015-08-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of human Roquin-2 and its complex with constitutive-decay element RNA
Acta Crystallogr.,Sect.F, 71, 2015
5UDK
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BU of 5udk by Molmil
IFIT1 monomeric mutant (L457E/L464E) with PPP-AAAA
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B.
Deposit date:2016-12-27
Release date:2017-03-01
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UDJ
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BU of 5udj by Molmil
IFIT1 monomeric mutant (L457E/L464E) with Gppp-AAAA
Descriptor: CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(G3A))-R(P*AP*AP*A)-3'), ...
Authors:Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B.
Deposit date:2016-12-27
Release date:2017-03-01
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UDI
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BU of 5udi by Molmil
IFIT1 monomeric mutant (L457E/L464E) with m7Gppp-AAAA (syn and anti conformations of cap)
Descriptor: CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3'), ...
Authors:Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B.
Deposit date:2016-12-27
Release date:2017-03-01
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UDL
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BU of 5udl by Molmil
IFIT1 N216A monomeric mutant (L457E/L464E) with m7Gppp-AAAA (anti conformation of cap)
Descriptor: CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3'), ...
Authors:Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B.
Deposit date:2016-12-27
Release date:2017-03-01
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3J7Q
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BU of 3j7q by Molmil
Structure of the idle mammalian ribosome-Sec61 complex
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2019-10-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
5X89
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BU of 5x89 by Molmil
The X-ray crystal structure of subunit fusion RNA splicing endonuclease from Methanopyrus kandleri
Descriptor: EndA-like protein,tRNA-splicing endonuclease, PHOSPHATE ION
Authors:Kaneta, A, Fujishima, K, Morikazu, W, Hori, H, Hirata, A.
Deposit date:2017-03-01
Release date:2018-01-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The RNA-splicing endonuclease from the euryarchaeaon Methanopyrus kandleri is a heterotetramer with constrained substrate specificity
Nucleic Acids Res., 46, 2018
6UU7
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BU of 6uu7 by Molmil
E. coli sigma-S transcription initiation complex with a 6-nt RNA and an NTP ("Old" crystal soaked with UTP, CTP, ddGTP, and dinucleotide ApG for 30 minutes)
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6ZU5
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BU of 6zu5 by Molmil
Structure of the Paranosema locustae ribosome in complex with Lso2
Descriptor: 18S rRNA, 25S rRNA, 5S rRNA, ...
Authors:Ehrenbolger, K, Jespersen, N, Sharma, H, Sokolova, Y.Y, Tokarev, Y.S, Vossbrinck, C.R, Barandun, J.
Deposit date:2020-07-21
Release date:2020-11-04
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Differences in structure and hibernation mechanism highlight diversification of the microsporidian ribosome.
Plos Biol., 18, 2020
6TYF
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BU of 6tyf by Molmil
Crystal structure of MTB sigma L transcription initiation complex with 6 nt long RNA primer
Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*AP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(P*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Molodtsov, V, Ebright, R.H.
Deposit date:2019-08-08
Release date:2020-03-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription.
Proc.Natl.Acad.Sci.USA, 117, 2020

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数据于2024-07-10公开中

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