7CJB
 
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7DNJ
 | | K63-polyUb MDA5CARDs complex | | Descriptor: | Interferon-induced helicase C domain-containing protein 1, Ubiquitin | | Authors: | Song, B, Chen, Y, Luo, D.H, Zheng, J. | | Deposit date: | 2020-12-09 | | Release date: | 2021-10-13 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Immunity, 54, 2021
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7DNI
 | | MDA5 CARDs-MAVS CARD polyUb complex | | Descriptor: | Interferon-induced helicase C domain-containing protein 1, Mitochondrial antiviral-signaling protein, Ubiquitin | | Authors: | Song, B, Chen, Y, Luo, D.H, Zheng, J. | | Deposit date: | 2020-12-09 | | Release date: | 2021-10-13 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Immunity, 54, 2021
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7F0U
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7F7X
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6WTG
 | | SdeA DUB Domain in complex with Ubiquitin | | Descriptor: | Ubiquitin, Ubiquitinating/deubiquitinating enzyme SdeA | | Authors: | Kenny, S, Sheedlo, M, Das, C. | | Deposit date: | 2020-05-02 | | Release date: | 2021-03-03 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.63 Å) | | Cite: | Insights into Ubiquitin Product Release in Hydrolysis Catalyzed by the Bacterial Deubiquitinase SdeA.
Biochemistry, 60, 2021
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6XZ1
 | | Conjugate of the HECT domain of HUWE1 with ubiquitin | | Descriptor: | HECT, UBA and WWE domain containing 1, isoform CRA_a, ... | | Authors: | Liu, B, Seenivasan, A, Nair, R, Chen, D, Lowe, E.D, Lorenz, S. | | Deposit date: | 2020-01-31 | | Release date: | 2021-08-25 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Reconstitution and Structural Analysis of a HECT Ligase-Ubiquitin Complex via an Activity-Based Probe.
Acs Chem.Biol., 16, 2021
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6XA9
 | | SARS CoV-2 PLpro in complex with ISG15 C-terminal domain propargylamide | | Descriptor: | GLYCEROL, ISG15 CTD-propargylamide, Non-structural protein 3, ... | | Authors: | Klemm, T, Calleja, D.J, Richardson, L.W, Lechtenberg, B.C, Komander, D. | | Deposit date: | 2020-06-04 | | Release date: | 2020-06-17 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2.
Embo J., 39, 2020
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6XAA
 | | SARS CoV-2 PLpro in complex with ubiquitin propargylamide | | Descriptor: | Non-structural protein 3, Ubiquitin-propargylamide, ZINC ION | | Authors: | Klemm, T, Calleja, D.J, Richardson, L.W, Lechtenberg, B.C, Komander, D. | | Deposit date: | 2020-06-04 | | Release date: | 2020-06-17 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2.
Embo J., 39, 2020
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2Z59
 | | Complex Structures of Mouse Rpn13 (22-130aa) and ubiquitin | | Descriptor: | Protein ADRM1, Ubiquitin | | Authors: | Chen, X, Schreiner, P, Groll, M, Walters, K.J. | | Deposit date: | 2007-07-01 | | Release date: | 2008-05-20 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction.
Nature, 453, 2008
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6YPT
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2ZNV
 | | Crystal structure of human AMSH-LP DUB domain in complex with Lys63-linked ubiquitin dimer | | Descriptor: | 1,2-ETHANEDIOL, AMSH-like protease, Ubiquitin, ... | | Authors: | Sato, Y, Azusa, Y, Yamagata, A, Mimura, H, Wang, X, Yamashita, M, Ookata, K, Nureki, O, Iwai, K, Komada, M, Fukai, S. | | Deposit date: | 2008-05-01 | | Release date: | 2008-09-02 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains
Nature, 455, 2008
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4G50
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2XBB
 | | Nedd4 HECT:Ub complex | | Descriptor: | E3 UBIQUITIN-PROTEIN LIGASE NEDD4, GLYCEROL, UBIQUITIN | | Authors: | Maspero, E, Cecatiello, V, Musacchio, A, Polo, S, Pasqualato, S. | | Deposit date: | 2010-04-08 | | Release date: | 2011-03-23 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Structure of the Hect:Ubiquitin Complex and its Role in Ubiquitin Chain Elongation
Embo Rep., 12, 2011
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4F8C
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4FJV
 | | Crystal Structure of Human Otubain2 and Ubiquitin Complex | | Descriptor: | ETHANAMINE, GLYCEROL, Polyubiquitin-C, ... | | Authors: | Altun, M, Walter, T.S, Kramer, H.B, Iphofer, A, David, Y, Komsany, A, Ternette, N, Nicholson, B, Navon, A, Stuart, D.I, Ren, J, Kessler, B.M. | | Deposit date: | 2012-06-12 | | Release date: | 2013-06-12 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.047 Å) | | Cite: | The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.
Plos One, 10, 2015
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4GGQ
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4FBJ
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2Y5B
 | | Structure of USP21 in complex with linear diubiquitin-aldehyde | | Descriptor: | SULFATE ION, UBIQUITIN, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 21, ... | | Authors: | Ye, Y, Akutsu, M, Reyes-Turcu, F, Enchev, R.I, Wilkinson, K.D, Komander, D. | | Deposit date: | 2011-01-12 | | Release date: | 2012-01-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Polyubiquitin Binding and Cross-Reactivity in the Usp Domain Deubiquitinase Usp21.
Embo Rep., 12, 2011
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4GIV
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2ZVO
 | | NEMO CoZi domain in complex with diubiquitin in C2 space group | | Descriptor: | NF-kappa-B essential modulator, UBC protein | | Authors: | Rahighi, S, Ikeda, F, Kawasaki, M, Akutsu, M, Suzuki, N, Kato, R, Kensche, T, Uejima, T, Bloor, S, Komander, D, Randow, F, Wakatsuki, S, Dikic, I. | | Deposit date: | 2008-11-12 | | Release date: | 2009-03-24 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009
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4HCN
 | | Crystal structure of Burkholderia pseudomallei effector protein CHBP in complex with ubiquitin | | Descriptor: | DI(HYDROXYETHYL)ETHER, FORMIC ACID, PHOSPHATE ION, ... | | Authors: | Yao, Q, Cui, J, Zhu, Y, Shao, F. | | Deposit date: | 2012-09-30 | | Release date: | 2012-11-21 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4HCP
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4FN2
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2ZVN
 | | NEMO CoZi domain incomplex with diubiquitin in P212121 space group | | Descriptor: | NF-kappa-B essential modulator, UBC protein | | Authors: | Rahighi, S, Ikeda, F, Kawasaki, M, Akutsu, M, Suzuki, N, Kato, R, Kensche, T, Uejima, T, Bloor, S, Komander, D, Randow, F, Wakatsuki, S, Dikic, I. | | Deposit date: | 2008-11-12 | | Release date: | 2009-03-24 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009
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