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6WKL
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BU of 6wkl by Molmil
Fab Fragment of Anti-human LAG3 antibody (BAP050)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAP050 Fab Heavy Chain, BAP050 Fab Light Chain
Authors:Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
Deposit date:2020-04-16
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Fab Fragment of Anti-human LAG3 antibody
To Be Published
5IF0
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BU of 5if0 by Molmil
Crystal structure of VRC01c-HuGL2 Fab from an HIV-1 naive donor in complex with with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.44 A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain eOD-GT8, PHOSPHATE ION, ...
Authors:Sarkar, A, Wilson, I.A.
Deposit date:2016-02-25
Release date:2016-04-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.
Science, 351, 2016
5IES
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BU of 5ies by Molmil
Crystal structure of VRC01c-HuGL2 Fab from an HIV-1 naive donor in complex with with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.16 A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Germline-targeting HIV-1 gp120 engineered outer domain eOD-GT8, ...
Authors:Sarkar, A, Wilson, I.A.
Deposit date:2016-02-25
Release date:2016-04-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.
Science, 351, 2016
5IFA
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BU of 5ifa by Molmil
Crystal structure of unbound VRC01c-HuGL2 Fab from an HIV-1 naive donor at 1.82 A
Descriptor: GLYCEROL, PENTAETHYLENE GLYCOL, SULFATE ION, ...
Authors:Sarkar, A, Wilson, I.A.
Deposit date:2016-02-25
Release date:2016-04-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.821 Å)
Cite:HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.
Science, 351, 2016
7RDW
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BU of 7rdw by Molmil
Crystal Structure of FH1 Fab bound to HXb2 HIV-1 gp120 core
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ...
Authors:Weidle, C, Pancera, M.
Deposit date:2021-07-12
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain.
Sci Adv, 8, 2022
7RPU
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BU of 7rpu by Molmil
Crystal Structure of Protective Human Antibody 3A6 Fab Against Ebola Virus with GP Stalk/MPER Epitope Peptide
Descriptor: 3A6 Fab heavy chain, 3A6 Fab light chain, GP2 epitope peptide
Authors:Salie, Z.L, Saphire, E.O, Davis, C.W, Ahmed, R.
Deposit date:2021-08-04
Release date:2022-07-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Protection against Ebola virus disease and neutralization mechanism of a survivor's anti-stalk-MPER antibody
To Be Published
7RPT
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BU of 7rpt by Molmil
Crystal Structure of Protective Human Antibody 3A6 Fab Against Ebola Virus
Descriptor: 3A6 Fab heavy chain, 3A6 Fab light chain
Authors:Salie, Z.L, Saphire, E.O, Davis, C.W, Ahmed, R.
Deposit date:2021-08-04
Release date:2022-07-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Protection against Ebola virus disease and neutralization mechanism of a survivor's anti-stalk/MPER antibody
To Be Published
5I76
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BU of 5i76 by Molmil
Crystal structure of FM318, a recombinant Fab adopted from cetuximab
Descriptor: FM318_heavy_cahin, FM318_light_chain
Authors:Sim, D.W, Kim, J.H, Seok, S.H, Seo, M.D, Kim, Y.P, Won, H.S.
Deposit date:2016-02-16
Release date:2016-12-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.922 Å)
Cite:Bacterial production and structure-functional validation of a recombinant antigen-binding fragment (Fab) of an anti-cancer therapeutic antibody targeting epidermal growth factor receptor.
Appl.Microbiol.Biotechnol., 100, 2016
7N7F
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BU of 7n7f by Molmil
Mouse norovirus (MNV-1) capsid at pH 7.5
Descriptor: Capsid protein
Authors:Smith, T.J.
Deposit date:2021-06-10
Release date:2021-09-08
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Multiple Signals in the Gut Contract the Mouse Norovirus Capsid To Block Antibody Binding While Enhancing Receptor Affinity.
J.Virol., 95, 2021
7N6Y
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BU of 7n6y by Molmil
Mouse norovirus (MNV-1) capsid at pH 5.0
Descriptor: Capsid protein
Authors:Smith, T.J.
Deposit date:2021-06-09
Release date:2021-09-08
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Multiple Signals in the Gut Contract the Mouse Norovirus Capsid To Block Antibody Binding While Enhancing Receptor Affinity.
J.Virol., 95, 2021
1CG9
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BU of 1cg9 by Molmil
COMPLEX RECOGNITION OF THE SUPERTYPIC BW6-DETERMINANT ON HLA-B AND-C MOLECULES BY THE MONOCLONAL ANTIBODY SFR8-B6
Descriptor: PROTEIN (BETA-2-MICROGLOBULIN), PROTEIN (EBNA-6 NUCLEAR PROTEIN (EBNA-3C) (EBNA-4B)), PROTEIN (HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Menssen, R, Orth, P, Ziegler, A, Saenger, W.
Deposit date:1999-03-25
Release date:2003-11-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Complex Recognition of the Supertypic Bw6-Determinant on HLA-B and-C Molecules by the Monoclonal Antibody SFR8-B6
To be Published
6LCS
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BU of 6lcs by Molmil
Crystal structure of 73MuL9 Fv-clasp fragment in complex with GA-pyridine analogue
Descriptor: (2~{S})-6-[4-(hydroxymethyl)-3-oxidanyl-pyridin-1-ium-1-yl]-2-(phenylmethoxycarbonylamino)hexanoic acid, PHOSPHATE ION, VH-SARAH, ...
Authors:Nakamura, T, Takagi, J, Yamagata, Y, Morioka, H.
Deposit date:2019-11-19
Release date:2020-11-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular recognition of a single-chain Fv antibody specific for GA-pyridine, an advanced glycation end-product (AGE), elucidated using biophysical techniques and synthetic antigen analogues.
J.Biochem., 170, 2021
6QCU
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BU of 6qcu by Molmil
Crystal structure of a Fab portion of the anti EBOV 3T0331 antibody
Descriptor: Heavy chain, Light chain, SULFATE ION
Authors:Diskin, R, Cohen-Dvashi, H.
Deposit date:2018-12-31
Release date:2019-10-02
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:rVSV-ZEBOV induces a polyclonal and convergent B cell response with potent Ebola virus-neutralizing antibodies
Nat.Med. (N.Y.), 2019
8R1C
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BU of 8r1c by Molmil
SD1-2 Fab in complex with SARS-CoV-2 BA.2.12.1 Spike Glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SD1-2 fab heavy chain, SD1-2 fab light chain, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2023-11-01
Release date:2024-03-13
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86.
Nat Commun, 15, 2024
6PPG
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BU of 6ppg by Molmil
Crystal structure of IL17FF bound to Fab fragments of MCAF5352A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, Fab MCAF5352A heavy chain, ...
Authors:Huang, C.S, Yin, J.P, Hymowitz, S.G.
Deposit date:2019-07-06
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Dissecting the molecular basis of high viscosity of monospecific and bispecific IgG antibodies.
Mabs, 12
5TJW
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BU of 5tjw by Molmil
Influenza A virus Nucleoprotein in Complex with Inhibitory Nanobody
Descriptor: NP-specific inhibitory VHH, Nucleoprotein
Authors:Hanke, L, Knockenhauer, K.E, Ploegh, H.L, Schwartz, T.U.
Deposit date:2016-10-05
Release date:2016-12-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.231 Å)
Cite:The Antiviral Mechanism of an Influenza A Virus Nucleoprotein-Specific Single-Domain Antibody Fragment.
MBio, 7, 2016
5UCB
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BU of 5ucb by Molmil
Structure of antigen-Fab complex with engineered switch residue region.
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS)
Deposit date:2016-12-22
Release date:2017-12-27
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.521 Å)
Cite:Antibody Switch Residue Engineering for Improved Crystallization Chaperones
To Be Published
8G30
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BU of 8g30 by Molmil
N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with 4 FNI19 Fab molecules
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FNI19 Fab heavy chain, ...
Authors:Dang, H.V, Snell, G.
Deposit date:2023-02-06
Release date:2023-05-31
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature, 618, 2023
5UEA
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BU of 5uea by Molmil
Structure of antigen-Fab complex with Histone chaperone ASF1
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A.
Deposit date:2016-12-29
Release date:2018-01-10
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Antibody Switch Residue Engineering for Improved Crystallization Chaperones
To Be Published
7L6O
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BU of 7l6o by Molmil
Cryo-EM structure of HIV-1 Env CH848.3.D0949.10.17chim.6R.DS.SOSIP.664
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 - gp120, ...
Authors:Manne, K, Edwards, R.J, Acharya, P.
Deposit date:2020-12-23
Release date:2021-04-14
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
5CZX
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BU of 5czx by Molmil
Crystal structure of Notch3 NRR in complex with 20358 Fab
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 20358 Fab heavy chain, ...
Authors:Hu, T, Fryer, C, Chopra, R, Clark, K.
Deposit date:2015-08-01
Release date:2016-06-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
Oncogene, 35, 2016
7L8Y
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BU of 7l8y by Molmil
BG505 SOSIP.v5.2 N241/N289 in complex with the polyclonal Fab pAbC-5 from animal Rh.33311 (Wk26 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2 N241/N289 - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Cannac, F, Ward, A.B.
Deposit date:2021-01-01
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8Z
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BU of 7l8z by Molmil
BG505 SOSIP.v5.2 N241/N289 in complex with the polyclonal Fab pAbC-7 from animal Rh.33311 (Wk26 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2 N241/N289 - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Perrett, H.R, Ward, A.B.
Deposit date:2021-01-01
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L88
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BU of 7l88 by Molmil
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-3 from animal Rh.32034 (Wk26 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Cannac, F, Perrett, H.R, Ward, A.B.
Deposit date:2020-12-31
Release date:2021-08-04
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8G
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BU of 7l8g by Molmil
BG505 SOSIP.v5.2(7S) in complex with the polyclonal Fab pAbC-3 from animal Rh.33172 (Wk38 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Antanasijevic, A, Sewall, L.M, Rantalainen, K, Ward, A.B.
Deposit date:2020-12-31
Release date:2021-08-04
Last modified:2021-09-08
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021

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数据于2024-07-24公开中

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