PDB: 13252 resultsInfo pagesStatus searchChemie searchBIRD

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2R18	Structural insights into the multifunctional protein VP3 of Birnaviruses Descriptor: Capsid assembly protein VP3 Authors: Casanas, A, Navarro, A, Ferrer-Orta, C, Gonzalez, D, Rodriguez, J.F, Verdaguer, N. Deposit date: 2007-08-22 Release date: 2008-02-05 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural insights into the multifunctional protein VP3 of birnaviruses. Structure, 16, 2008
3E0D	Insights into the Replisome from the Crystral Structure of the Ternary Complex of the Eubacterial DNA Polymerase III alpha-subunit Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase III subunit alpha, ... Authors: Wing, R.A, Bailey, S, Steitz, T.A. Deposit date: 2008-07-31 Release date: 2008-09-23 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (4.6 Å) Cite: Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III alpha-Subunit. J.Mol.Biol., 382, 2008
3AU2	DNA polymerase X from Thermus thermophilus HB8 complexed with Ca-dGTP Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... Authors: Nakane, S, Ishikawa, H, Wakamatsu, T, Nakagawa, N, Masui, R, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2011-01-28 Release date: 2012-01-25 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.4 Å) Cite: The structural basis of the kinetic mechanism of a gap-filling X-family DNA polymerase that binds Mg(2+)-dNTP before binding to DNA. J.Mol.Biol., 417, 2012
2KY6	Structure of ARC92VBD/MED25ACID Descriptor: Mediator of RNA polymerase II transcription subunit 25 Authors: Milbradt, A.G, Sun, Z.J, Selenko, P, Takeuchi, K, Naar, A.M, Wagner, G. Deposit date: 2010-05-14 Release date: 2011-03-09 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structure of the VP16 transactivator target in the Mediator. Nat.Struct.Mol.Biol., 18, 2011
2KX2	The solution structure of MTH1821 Descriptor: Putative uncharacterized protein Authors: Lee, W, Ko, S, Structural Genomics Consortium (SGC) Deposit date: 2010-04-23 Release date: 2011-04-27 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Solution structure of MTH1821, a putative structure homologue to RNA polymerase alpha subunit from Methanobacterium thermoautotrophicum. Proteins, 79, 2011
2MAP	Solution structure of the complex formed by the region 2 of E. coli sigmaE and its cognate -10 promoter element non template strand TGTCAAA. Descriptor: DNA, RNA polymerase sigma factor Authors: Campagne, S, Vorholt, J.A, Allain, F.H.-T. Deposit date: 2013-07-16 Release date: 2014-02-19 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural basis for -10 promoter element melting by environmentally induced sigma factors. Nat.Struct.Mol.Biol., 21, 2014
2RUH	Chemical Shift Assignments for MIP and MDM2 in bound state Descriptor: E3 ubiquitin-protein ligase Mdm2 Authors: Nagata, T, Shirakawa, K, Kobayashi, N, Shiheido, H, Horisawa, K, Katahira, M, Doi, N, Yanagawa, H. Deposit date: 2014-06-03 Release date: 2014-10-15 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural Basis for Inhibition of the MDM2:p53 Interaction by an Optimized MDM2-Binding Peptide Selected with mRNA Display Plos One, 9, 2014
6M7O	Human DNA polymerase eta ternary complex with Mn2+ and dTMPNPP oppositing cdA Descriptor: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*AP*TP*(02I)P*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(P*AP*GP*TP*GP*TP*GP*AP*G*(1FZ))-3'), ... Authors: Weng, P, Gao, Y, Yang, W. Deposit date: 2018-08-20 Release date: 2018-09-12 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3 Å) Cite: Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6M7T	Human DNA polymerase eta in a non-productive ternary complex with Ca2+ and dTTP oppositing cdA Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), ... Authors: Weng, P, Gao, Y, Yang, W. Deposit date: 2018-08-21 Release date: 2018-09-12 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2L3T	Solution structure of tandem SH2 domain from Spt6 Descriptor: Transcription elongation factor SPT6 Authors: Liu, J, Zhang, J, Wu, J, Shi, Y. Deposit date: 2010-09-22 Release date: 2011-06-15 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure of the tandem SH2 domains from Spt6 and their binding to the phosphorylated RNA polymerase II C-terminal domain To be Published
2L23	NMR structure of the ACID (ACtivator Interacting Domain) of the human mediator Med25 protein Descriptor: Mediator of RNA polymerase II transcription subunit 25 Authors: Bontems, F, Monte, D, Dewitte, F, Villeret, V. Deposit date: 2010-08-10 Release date: 2010-11-24 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: NMR structure of the human Mediator MED25 ACID domain. J.Struct.Biol., 174, 2011
6M7U	Human DNA polymerase eta in a non-productive ternary complex with Mg2+ and dTMPNPP oppositing cdA Descriptor: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, CHLORIDE ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), ... Authors: Weng, P, Gao, Y, Yang, W. Deposit date: 2018-08-21 Release date: 2018-09-12 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5DGB	CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA EXTENDING AN 1,N6-ETHENODEOXYADENOSINE : dA PAIR BY INSERTING dTMPNPP OPPOSITE TEMPLATE dA Descriptor: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*A)-3'), DNA (5'-D(*CP*AP*TP*AP*(EDA)P*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Patra, A, Egli, M. Deposit date: 2015-08-27 Release date: 2016-06-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta. J.Biol.Chem., 291, 2016
4EEY	Crystal structure of human DNA polymerase eta in ternary complex with a cisplatin DNA adduct Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*TP*GP*GP*TP*CP*TP*CP*CP*TP*CP*C)-3', 5'-D(*TP*GP*GP*AP*GP*GP*AP*GP*A)-3', ... Authors: Ummat, A, Rechkoblit, O, Jain, R, Choudhury, J.R, Johnson, R.E, Silverstein, T.D, Buku, A, Lone, S, Prakash, L, Prakash, S, Aggarwal, A.K. Deposit date: 2012-03-28 Release date: 2012-05-09 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Structural basis for cisplatin DNA damage tolerance by human polymerase {eta} during cancer chemotherapy. Nat.Struct.Mol.Biol., 19, 2012
5DG8	CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING dAMPNPP ACROSS A DNA TEMPLATE CONTAINING 1,N6-ETHENODEOXYADENOSINE LESION Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(EDA)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Patra, A, Egli, M. Deposit date: 2015-08-27 Release date: 2016-06-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta. J.Biol.Chem., 291, 2016
5DG7	CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING dTTP ACROSS A DNA TEMPLATE CONTAINING 1,N6-ETHENODEOXYADENOSINE LESION Descriptor: CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(EDA)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Patra, A, Egli, M. Deposit date: 2015-08-27 Release date: 2016-06-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta. J.Biol.Chem., 291, 2016
6BRX	Crystal Structure of Human DNA polymerase kappa in complex with DNA containing the major cisplatin lesion Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Cisplatin, DI(HYDROXYETHYL)ETHER, ... Authors: Jha, V.K, Ling, H. Deposit date: 2017-12-01 Release date: 2018-08-22 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender. J. Mol. Biol., 430, 2018
6BS1	Crystal Structure of Human DNA polymerase kappa in complex with DNA containing the major cisplatin lesion Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Cisplatin, DNA (5'-D(*TP*AP*CP*TP*GP*GP*TP*AP*TP*GP*TP*AP*T)-3'), ... Authors: Jha, V.K, Ling, H. Deposit date: 2017-12-01 Release date: 2018-08-22 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender. J. Mol. Biol., 430, 2018
4ED7	Human DNA polymerase eta - DNA ternary complex: TG crystal at pH 7.0 (K+ MES) with 1 Ca2+ ion Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*G)-3'), ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-27 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.717 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4ECY	Human DNA polymerase eta - DNA ternary complex: AT crystal at pH 6.0 (Na+ MES) with 1 Ca2+ ion Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.943 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4ED6	Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 6.7 for 15 hr, Sideway translocation Descriptor: DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-27 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.211 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4ECQ	Human DNA polymerase eta- DNA ternary complex: AT crystal at pH6.8(K+ MES) with 1 Ca2+ ion Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4D7X	Solution Structure of the Mediator Gall11 KIX Domain of C. Glabrata Descriptor: MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 Authors: Boeszoermenyi, A, Wagner, G, Naar, A.M, Arthanari, H. Deposit date: 2014-11-30 Release date: 2015-12-09 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Inhibiting Fungal Multidrug Resistance by Disrupting an Activator-Mediator Interaction. Nature, 530, 2016
1MMI	E. COLI DNA POLYMERASE BETA SUBUNIT Descriptor: DNA polymerase III, beta chain Authors: Oakley, A.J, Prosselkov, P, Wijffels, G, Beck, J.L, Wilce, M.C.J, Dixon, N.E. Deposit date: 2002-09-04 Release date: 2003-09-04 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.848 Å) Cite: Flexibility revealed by the 1.85 A crystal structure of the beta sliding-clamp subunit of Escherichia coli DNA polymerase III. Acta Crystallogr.,Sect.D, 59, 2003
4ED3	Human DNA polymerase eta - DNA ternary complex: AT crystal at pH 7.5 (Na+ HEPES) with 1 Ca2+ ion Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.791 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012

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