Human DNA polymerase eta - DNA ternary complex: AT crystal at pH 6.0 (Na+ MES) with 1 Ca2+ ion

Summary for 4ECY

Related4ECQ 4ECR 4ECS 4ECT 4ECU 4ECV 4ECW 4ECX 4ECZ 4ED0 4ED1 4ED2 4ED3 4ED6 4ED7 4ED8
DescriptorDNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... (7 entities in total)
Functional Keywordstransferase-dna complex, transferase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q9Y253
Total number of polymer chains3
Total molecular weight55489.26
Nakamura, T.,Zhao, Y.,Yang, W. (deposition date: 2012-03-26, release date: 2012-07-11, Last modification date: 2012-07-25)
Primary citation
Nakamura, T.,Zhao, Y.,Yamagata, Y.,Hua, Y.J.,Yang, W.
Watching DNA polymerase eta make a phosphodiester bond
Nature, 487:196-201, 2012
PubMed: 22785315 (PDB entries with the same primary citation)
DOI: 10.1038/nature11181
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2334 0.2% 0.5% 6.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-28