Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 7.0 for 250 sec

Summary for 4ECW

Related4ECQ 4ECR 4ECS 4ECT 4ECU 4ECV 4ECX 4ECY 4ECZ 4ED0 4ED1 4ED2 4ED3 4ED6 4ED7 4ED8
DescriptorDNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ... (9 entities in total)
Functional Keywordstransferase-dna complex, transferase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q9Y253
Total number of polymer chains3
Total molecular weight56049.32
Nakamura, T.,Zhao, Y.,Yang, W. (deposition date: 2012-03-26, release date: 2012-07-11, Last modification date: 2012-07-25)
Primary citation
Nakamura, T.,Zhao, Y.,Yamagata, Y.,Hua, Y.J.,Yang, W.
Watching DNA polymerase eta make a phosphodiester bond
Nature, 487:196-201, 2012
PubMed: 22785315 (PDB entries with the same primary citation)
DOI: 10.1038/nature11181
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2133 0.2% 1.4% 5.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21