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6M7T

Human DNA polymerase eta in a non-productive ternary complex with Ca2+ and dTTP oppositing cdA

Summary for 6M7T
Entry DOI10.2210/pdb6m7t/pdb
DescriptorDNA polymerase eta, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), DNA (5'-D(*AP*TP*(02I)P*CP*TP*CP*AP*CP*AP*CP*T)-3'), ... (9 entities in total)
Functional Keywordstranslesion synthesis, cda, dna binding protein, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains3
Total formula weight55318.82
Authors
Weng, P.,Gao, Y.,Yang, W. (deposition date: 2018-08-21, release date: 2018-09-12, Last modification date: 2023-10-11)
Primary citationWeng, P.J.,Gao, Y.,Gregory, M.T.,Wang, P.,Wang, Y.,Yang, W.
Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 115:10660-10665, 2018
Cited by
PubMed: 30275308
DOI: 10.1073/pnas.1812856115
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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