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6M7T

Human DNA polymerase eta in a non-productive ternary complex with Ca2+ and dTTP oppositing cdA

Functional Information from GO Data
ChainGOidnamespacecontents
A0003684molecular_functiondamaged DNA binding
A0006281biological_processDNA repair
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue NI A 501
ChainResidue
AASP181
AHIS289
AHIS393
AHIS397

site_idAC2
Number of Residues15
Detailsbinding site for residue TTP A 502
ChainResidue
APHE18
AILE48
ATYR52
AARG55
AARG61
AASP115
ALYS231
ACA503
TDA2
T02I4
AASP13
AMET14
AASP15
ACYS16
APHE17

site_idAC3
Number of Residues4
Detailsbinding site for residue CA A 503
ChainResidue
AASP13
AMET14
AASP115
ATTP502

site_idAC4
Number of Residues2
Detailsbinding site for residue EDO A 504
ChainResidue
AARG382
APHE423

site_idAC5
Number of Residues4
Detailsbinding site for residue GOL A 505
ChainResidue
ATHR282
AGLU283
ASER284
ATYR299

site_idAC6
Number of Residues5
Detailsbinding site for residue GOL A 506
ChainResidue
ASER257
ALEU262
ALYS293
AASN294
ATRP297

site_idAC7
Number of Residues5
Detailsbinding site for residue GOL A 507
ChainResidue
AASP181
ALEU183
AGLN280
APHE281
AGLN285

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO
ChainResidueDetails
AASP13
AMET14
AASP115
AGLU116

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:27284197
ChainResidueDetails
AARG61

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PDB entries from 2024-11-06

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