6M7T

Human DNA polymerase eta in a non-productive ternary complex with Ca2+ and dTTP oppositing cdA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue NI A 501

Chain	Residue
A	ASP181
A	HIS289
A	HIS393
A	HIS397

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site_id	AC2
Number of Residues	15
Details	binding site for residue TTP A 502

Chain	Residue
A	PHE18
A	ILE48
A	TYR52
A	ARG55
A	ARG61
A	ASP115
A	LYS231
A	CA503
T	DA2
T	02I4
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17

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site_id	AC3
Number of Residues	4
Details	binding site for residue CA A 503

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	TTP502

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site_id	AC4
Number of Residues	2
Details	binding site for residue EDO A 504

Chain	Residue
A	ARG382
A	PHE423

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site_id	AC5
Number of Residues	4
Details	binding site for residue GOL A 505

Chain	Residue
A	THR282
A	GLU283
A	SER284
A	TYR299

---

site_id	AC6
Number of Residues	5
Details	binding site for residue GOL A 506

Chain	Residue
A	SER257
A	LEU262
A	LYS293
A	ASN294
A	TRP297

---

site_id	AC7
Number of Residues	5
Details	binding site for residue GOL A 507

Chain	Residue
A	ASP181
A	LEU183
A	GLN280
A	PHE281
A	GLN285

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KFO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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