6M7T
Human DNA polymerase eta in a non-productive ternary complex with Ca2+ and dTTP oppositing cdA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase eta | polymer | 435 | 48617.7 | 1 | UniProt (Q9Y253) Pfam (PF00817) Pfam (PF21704) Pfam (PF11799) | Homo sapiens (Human) | RAD30 homolog A,Xeroderma pigmentosum variant type protein |
| 2 | B (P) | DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3') | polymer | 8 | 2506.7 | 1 | Homo sapiens | ||
| 3 | C (T) | DNA (5'-D(*AP*TP*(02I)P*CP*TP*CP*AP*CP*AP*CP*T)-3') | polymer | 11 | 3275.2 | 1 | Homo sapiens | ||
| 4 | D (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 5 | E (A) | THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 482.2 | 1 | Chemie (TTP) | |||
| 6 | F (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 8 | H, I, J (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 9 | K, L, M (A, P, T) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 54399.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 919.3 | |
| All* | Total formula weight | 55318.8 |
