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8QPY
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BU of 8qpy by Molmil
Solution NMR structure of the peptidyl carrier domain TomAPCP from the Tomaymycin non-ribosomal peptide synthetase
Descriptor: Carrier protein TomAPCP
Authors:Karanth, M.N, Kirkpatrick, J.P, Carlomagno, T.
Deposit date:2023-10-03
Release date:2024-06-26
Last modified:2024-07-03
Method:SOLUTION NMR
Cite:The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain.
Sci Adv, 10, 2024
8QSX
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BU of 8qsx by Molmil
Solution NMR structure of the novel adaptor domain TomBN91 from the Tomaymycin non-ribosomal peptide synthetase
Descriptor: TomBN91
Authors:Karanth, M.N, Kirkpatrick, J.P, Carlomagno, T.
Deposit date:2023-10-11
Release date:2024-06-26
Last modified:2024-07-03
Method:SOLUTION NMR
Cite:The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain.
Sci Adv, 10, 2024
8QRX
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BU of 8qrx by Molmil
Solution NMR structure of the peptidyl carrier domain TomAPCP from the Tomaymycin non-ribosomal peptide synthetase in its substrate-loaded state
Descriptor: TomAPCP substrate-loaded from the Tomaymycin non-ribosomal peptide synthetase
Authors:Karanth, M.N, Kirkpatrick, J.P, Carlomagno, T.
Deposit date:2023-10-09
Release date:2024-06-26
Last modified:2024-07-03
Method:SOLUTION NMR
Cite:The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain.
Sci Adv, 10, 2024
6YQ5
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BU of 6yq5 by Molmil
Hybrid structure of the SPP1 tail tube by solid-state NMR and cryo EM - NMR Ensemble
Descriptor: Tail tube protein gp17.1*
Authors:Zinke, M, Sachowsky, K.A.A, Zinn-Justin, S, Ravelli, R, Schroder, G.F, Habeck, M, Lange, A.
Deposit date:2020-04-16
Release date:2020-10-14
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4 Å), SOLID-STATE NMR
Cite:Architecture of the flexible tail tube of bacteriophage SPP1.
Nat Commun, 11, 2020
6WA3
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BU of 6wa3 by Molmil
Solution NMR structure of the myristoylated feline immunodeficiency virus matrix protein
Descriptor: MYRISTIC ACID, Matrix protein
Authors:Brown, J.B, Summers, H.R, Brown, L.A, Marchant, J, Canova, P.N, O'Hern, C.T, Abbott, S, Nyaunu, C, Maxwell, S, Johnson, T, Moser, M, Ablan, S.D, Carter, H, Freed, E.O, Summers, M.F.
Deposit date:2020-03-24
Release date:2020-07-22
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and Mechanistic Studies of the Rare Myristoylation Signal of the Feline Immunodeficiency Virus.
J.Mol.Biol., 432, 2020
8SCH
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BU of 8sch by Molmil
TCEI_III NMR Structure
Descriptor: RNA (68-MER)
Authors:Warden, M.S, Mueller, G.A, Hall, T.M.T.
Deposit date:2023-04-05
Release date:2023-07-12
Last modified:2024-05-15
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:The translational repressor Glorund uses interchangeable RNA recognition domains to recognize Drosophila nanos.
Nucleic Acids Res., 51, 2023
8SCF
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BU of 8scf by Molmil
TCEIII NMR Structure
Descriptor: RNA (30-MER)
Authors:Warden, M.S, Mueller, G.A, Hall, T.M.T.
Deposit date:2023-04-05
Release date:2023-07-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The translational repressor Glorund uses interchangeable RNA recognition domains to recognize Drosophila nanos.
Nucleic Acids Res., 51, 2023
6WA4
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BU of 6wa4 by Molmil
Solution NMR structure of the unmyristoylated feline immunodeficiency virus matrix protein
Descriptor: Matrix protein
Authors:Brown, J.B, Summers, H.R, Brown, L.A, Marchant, J, Canova, P.N, O'Hern, C.T, Abbott, S.T, Nyaunu, C, Maxwell, S, Johnson, T, Moser, M.B, Carter, H, Ablan, S, Freed, E.O, Summers, M.F.
Deposit date:2020-03-24
Release date:2020-07-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural and Mechanistic Studies of the Rare Myristoylation Signal of the Feline Immunodeficiency Virus.
J.Mol.Biol., 432, 2020
6WA5
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BU of 6wa5 by Molmil
Solution NMR Structure of the G4L/Q5K/G6S (NOS) Unmyristoylated Feline Immunodeficiency Virus Matrix Protein
Descriptor: Matrix protein
Authors:Brown, J.B, Summers, H.R, Brown, L.A, Marchant, J, Canova, P.N, O'Hern, C.T, Abbott, S.T, Nyaunu, C, Maxwell, S, Johnson, T, Moser, M.B, Ablan, S.A, Carter, H, Freed, E.O, Summers, M.F.
Deposit date:2020-03-24
Release date:2020-07-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural and Mechanistic Studies of the Rare Myristoylation Signal of the Feline Immunodeficiency Virus.
J.Mol.Biol., 432, 2020
4ECE
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BU of 4ece by Molmil
Crystal structure of purine nucleoside phosphorylase (W16Y, W94Y, W178Y, H257W) mutant from human complexed with guanine
Descriptor: GUANINE, Purine nucleoside phosphorylase
Authors:Haapalainen, A.M, Ho, M.C, Suarez, J.J, Almo, S.C, Schramm, V.L.
Deposit date:2012-03-26
Release date:2013-02-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Catalytic Site Conformations in Human PNP by (19)F-NMR and Crystallography.
Chem.Biol., 20, 2013
4EB8
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BU of 4eb8 by Molmil
Crystal structure of purine nucleoside phosphorylase (W16Y, W94Y, W178Y, H257W) mutant from human complexed with DADMe-ImmG and phosphate
Descriptor: 1,2-ETHANEDIOL, 2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, PHOSPHATE ION, ...
Authors:Ho, M.C, Haapalainen, A.M, Suarez, J.J, Almo, S.C, Schramm, V.L.
Deposit date:2012-03-23
Release date:2013-02-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Catalytic Site Conformations in Human PNP by (19)F-NMR and Crystallography.
Chem.Biol., 20, 2013
4EAR
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BU of 4ear by Molmil
Crystal structure of purine nucleoside phosphorylase (W16Y, W94Y, W178Y, H257W) mutant from human complexed with DADMe-ImmG and phosphate
Descriptor: 2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, PHOSPHATE ION, Purine nucleoside phosphorylase
Authors:Haapalainen, A.M, Ho, M.C, Suarez, J.J, Almo, S.C, Schramm, V.L.
Deposit date:2012-03-22
Release date:2013-02-06
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Catalytic Site Conformations in Human PNP by (19)F-NMR and Crystallography.
Chem.Biol., 20, 2013
7YYI
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BU of 7yyi by Molmil
Solution NMR structure of N-acetylglucosaminyltransferase V (GnTV) TMD
Descriptor: Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
Authors:Silber, M, Muhle-Goll, C.
Deposit date:2022-02-17
Release date:2022-12-28
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage.
Sci Rep, 12, 2022
5VKG
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BU of 5vkg by Molmil
Solution-state NMR structural ensemble of human Tsg101 UEV in complex with tenatoprazole
Descriptor: 4-methoxy-1-(5-methoxy-3H-imidazo[4,5-b]pyridin-2-yl)-3,5-dimethyl-2-(sulfanylmethyl)pyridin-1-ium, Tumor susceptibility gene 101 protein
Authors:Strickland, M, Ehrlich, L.S, Watanabe, S, Khan, M, Strub, M.-P, Luan, C.H, Powell, M.D, Leis, J, Tjandra, N, Carter, C.
Deposit date:2017-04-21
Release date:2017-11-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Tsg101 chaperone function revealed by HIV-1 assembly inhibitors.
Nat Commun, 8, 2017
4KV8
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BU of 4kv8 by Molmil
Crystal structure of HIV RT in complex with BILR0355BS
Descriptor: 11-ethyl-5-methyl-8-[2-(1-oxidanylquinolin-4-yl)oxyethyl]dipyrido[3,2-[1,4]diazepin-6-one, HIV Reverse transcriptase P51, HIV Reverse transcriptase P66, ...
Authors:Coulombe, R.
Deposit date:2013-05-22
Release date:2013-07-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:N- versus O-alkylation: Utilizing NMR methods to establish reliable primary structure determinations for drug discovery.
Bioorg.Med.Chem.Lett., 23, 2013
5VZM
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BU of 5vzm by Molmil
Solution NMR structure of human Rev1 (932-1039) in complex with ubiquitin
Descriptor: DNA repair protein REV1, Ubiquitin
Authors:Cui, G, Botuyan, M.V, Mer, G.
Deposit date:2017-05-29
Release date:2018-05-23
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Structural Basis for the Interaction of Mutasome Assembly Factor REV1 with Ubiquitin.
J. Mol. Biol., 430, 2018
6NJF
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BU of 6njf by Molmil
Solution NMR Structure of DANCER3-F34A, a rigid and natively folded single mutant of the dynamic protein DANCER-3
Descriptor: Immunoglobulin G-binding protein G
Authors:Damry, A.M, Mayer, M.M, Goto, N.K, Chica, R.A.
Deposit date:2019-01-03
Release date:2019-08-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Origin of conformational dynamics in a globular protein.
Commun Biol, 2, 2019
6NU0
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BU of 6nu0 by Molmil
Solution NMR structure of 1918 NS1 effector domain
Descriptor: Non-structural protein 1
Authors:Shen, Q, Cho, J.H.
Deposit date:2019-01-30
Release date:2020-01-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The structure and conformational plasticity of the nonstructural protein 1 of the 1918 influenza A virus.
Biochem.Biophys.Res.Commun., 518, 2019
7JGY
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BU of 7jgy by Molmil
Solution NMR structure of protonectin, a peptide from wasp
Descriptor: Protonectin peptide ILE-LEU-GLY-THR-ILE-LEU-GLY-LEU-LEU-LYS-GLY-LEU-NH2
Authors:Muller, J.A.I, Craik, D.J, Koehbach, J.
Deposit date:2020-07-20
Release date:2020-12-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Antimicrobial and Anticancer Properties of Synthetic Peptides Derived from the Wasp Parachartergus fraternus.
Chembiochem, 22, 2021
5H1D
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BU of 5h1d by Molmil
Crystal structure of C-terminal of RhoGDI2
Descriptor: Rho GDP-dissociation inhibitor 2
Authors:Liu, J.
Deposit date:2016-10-08
Release date:2016-10-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.494 Å)
Cite:NMR characterization of weak interactions between RhoGDI2 and fragment screening hits.
Biochim. Biophys. Acta, 1861, 2017
4TT5
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BU of 4tt5 by Molmil
Crystal Structure of CYP119 from Sulfolobus acidocaldarius, complexed with 4-(4-bromophenyl)-1H imidazole
Descriptor: 4-(4-bromophenyl)-1H-imidazole, Cytochrome P450 119, GLYCEROL, ...
Authors:Madrona, Y.
Deposit date:2014-06-19
Release date:2015-02-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:NMR and X-ray Analysis of CYP119 ligand-dependent conformational changes
To Be Published
1MFN
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BU of 1mfn by Molmil
SOLUTION NMR STRUCTURE OF LINKED CELL ATTACHMENT MODULES OF MOUSE FIBRONECTIN CONTAINING THE RGD AND SYNERGY REGIONS, 20 STRUCTURES
Descriptor: FIBRONECTIN
Authors:Copie, V, Tomita, Y, Akiyama, S.K, Aota, S, Yamada, K.M, Venable, R.M, Pastor, R.W, Krueger, S, Torchia, D.A.
Deposit date:1998-01-27
Release date:1998-04-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure and dynamics of linked cell attachment modules of mouse fibronectin containing the RGD and synergy regions: comparison with the human fibronectin crystal structure.
J.Mol.Biol., 277, 1998
8TB1
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BU of 8tb1 by Molmil
Solution NMR structure of a RiPP proteusin precursor protein
Descriptor: NHLP leader peptide family natural product, tumor homing peptide 1 (TH1) substrate chimera
Authors:McShan, A.C, Vinayak, A, Nguyen, N.A.
Deposit date:2023-06-28
Release date:2024-02-14
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Disordered regions in proteusin peptides guide post-translational modification by a flavin-dependent RiPP brominase.
Nat Commun, 15, 2024
6XV2
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BU of 6xv2 by Molmil
Full structure of RYMV P1 protein, derived from crystallographic and NMR data.
Descriptor: ZINC ION, p1
Authors:Poignavent, V, Hoh, F, Vignols, F, Demene, H, Yang, Y, Gillet, F.X.
Deposit date:2020-01-21
Release date:2021-02-03
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:A Flexible and Original Architecture of Two Unrelated Zinc Fingers Underlies the Role of the Multitask P1 in RYMV Spread.
J.Mol.Biol., 434, 2022
6VGQ
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BU of 6vgq by Molmil
ClpP1P2 complex from M. tuberculosis with GLF-CMK bound to ClpP1
Descriptor: ATP-dependent Clp protease proteolytic subunit, ATP-dependent Clp protease proteolytic subunit 1, Z-Gly-leu-phe-CH2Cl
Authors:Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E.
Deposit date:2020-01-08
Release date:2020-03-18
Last modified:2020-04-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:An allosteric switch regulatesMycobacterium tuberculosisClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR.
Proc.Natl.Acad.Sci.USA, 117, 2020

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数据于2024-07-10公开中

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