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6D0S
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BU of 6d0s by Molmil
RabGAP domain of human TBC1D22B
Descriptor: SULFATE ION, TBC1 domain family member 22B, UNKNOWN ATOM OR ION
Authors:Tong, Y, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2018-04-10
Release date:2018-06-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:RabGAP domain of human TBC1D22B
To be Published
4V01
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BU of 4v01 by Molmil
FGFR1 in complex with ponatinib (co-crystallisation).
Descriptor: 1,2-ETHANEDIOL, 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, ...
Authors:Tucker, J, Klein, T, Breed, J, Breeze, A, Overman, R, Phillips, C, Norman, R.A.
Deposit date:2014-09-10
Release date:2014-12-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structural Insights Into Fgfr Kinase Isoform Selectivity: Diverse Binding Modes of Azd4547 and Ponatinib in Complex with Fgfr1 and Fgfr4
Structure, 22, 2014
4USI
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BU of 4usi by Molmil
Nitrogen regulatory protein PII from Chlamydomonas reinhardtii in complex with MgATP and 2-oxoglutarate
Descriptor: 2-OXOGLUTARIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Chellamuthu, V.R, Forchhammer, K, Hartmann, M.D.
Deposit date:2014-07-08
Release date:2014-12-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:A Widespread Glutamine-Sensing Mechanism in the Plant Kingdom.
Cell(Cambridge,Mass.), 159, 2014
9CK7
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BU of 9ck7 by Molmil
Lineage IV Lassa virus glycoprotein (Josiah) in complex with polyclonal antibody (GPC-A epitope) from rabbit 187
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Brouwer, P.J.M, Perrett, H.R, Ward, A.B.
Deposit date:2024-07-08
Release date:2024-09-25
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses.
Cell Rep, 43, 2024
4UXL
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BU of 4uxl by Molmil
Structure of Human ROS1 Kinase Domain in Complex with PF-06463922
Descriptor: (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS
Authors:McTigue, M, Deng, Y, Liu, W, Brooun, A, Stewart, A.
Deposit date:2014-08-25
Release date:2015-03-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Pf-06463922 is a Potent and Selective Next-Generation Ros1/Alk Inhibitor Capable of Blocking Crizotinib-Resistant Ros1 Mutations.
Proc.Natl.Acad.Sci.USA, 112, 2015
9CJ7
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BU of 9cj7 by Molmil
Lineage IV Lassa virus glycoprotein (Josiah) in complex with monoclonal antibody 8.9F
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Brouwer, P.J.M, Perrett, H.R, Ward, A.B.
Deposit date:2024-07-05
Release date:2024-09-25
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses.
Cell Rep, 43, 2024
9CJ8
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BU of 9cj8 by Molmil
Lineage IV Lassa virus glycoprotein (Josiah) in complex with rabbit polyclonal antibody (LAVA01-like epitope)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Brouwer, P.J.M, Perrett, H.R, Ward, A.B.
Deposit date:2024-07-05
Release date:2024-09-25
Last modified:2025-05-21
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses.
Cell Rep, 43, 2024
2BT9
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BU of 2bt9 by Molmil
Lectin from Ralstonia solanacearum complexed with Me-fucoside
Descriptor: LECTIN, methyl alpha-L-fucopyranoside
Authors:Mitchell, E.P, Kostlanova, N, Wimmerova, M, Imberty, A.
Deposit date:2005-05-27
Release date:2005-06-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (0.94 Å)
Cite:The fucose-binding lectin from Ralstonia solanacearum. A new type of beta-propeller architecture formed by oligomerization and interacting with fucoside, fucosyllactose, and plant xyloglucan.
J. Biol. Chem., 280, 2005
2BYP
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BU of 2byp by Molmil
Crystal structure of Aplysia californica AChBP in complex with alpha- conotoxin ImI
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-CONOTOXIN IMI, SOLUBLE ACETYLCHOLINE RECEPTOR
Authors:Hansen, S.B, Sulzenbacher, G, Huxford, T, Marchot, P, Taylor, P, Bourne, Y.
Deposit date:2005-08-03
Release date:2005-10-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations.
Embo J., 24, 2005
4V1W
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BU of 4v1w by Molmil
3D structure of horse spleen apoferritin determined by electron cryomicroscopy
Descriptor: FERRITIN LIGHT CHAIN
Authors:Russo, C.J, Passmore, L.A.
Deposit date:2014-10-02
Release date:2014-12-10
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Electron Microscopy. Ultrastable Gold Substrates for Electron Cryomicroscopy.
Science, 346, 2014
2BYW
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BU of 2byw by Molmil
Structure of Escherichia coli beta-ketoacyl (acyl carrier protein) synthase I LYS328ALA mutant
Descriptor: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I, AMMONIUM ION
Authors:Olsen, J.G, von Wettstein-Knowles, P, Henriksen, A.
Deposit date:2005-08-09
Release date:2005-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases.
FEBS J., 273, 2006
6CHH
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BU of 6chh by Molmil
Structure of human NNMT in complex with bisubstrate inhibitor MS2756
Descriptor: (2~{S})-5-[2-(3-aminocarbonylphenyl)ethyl-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]amino]-2-azanyl-pentanoic acid, 1,2-ETHANEDIOL, Nicotinamide N-methyltransferase
Authors:Babault, N, Liu, J, Jin, J.
Deposit date:2018-02-22
Release date:2018-06-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT).
J. Med. Chem., 61, 2018
4W74
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BU of 4w74 by Molmil
Crystal Structure of Full-Length Split GFP Mutant E115C/T118H With Metal Mediated Crystal Contacts, P 1 21 1 Space Group
Descriptor: ZINC ION, fluorescent protein E115C/T118H
Authors:Leibly, D.J, Waldo, G.S, Yeates, T.O.
Deposit date:2014-08-21
Release date:2015-02-18
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Suite of Engineered GFP Molecules for Oligomeric Scaffolding.
Structure, 23, 2015
2C5F
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BU of 2c5f by Molmil
Torpedo californica acetylcholinesterase in complex with a non hydrolysable substrate analogue, 4-oxo-N,N,N-trimethylpentanaminium
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4-DIHYDROXY-N,N,N-TRIMETHYLPENTAN-1-AMINIUM, ACETYLCHOLINESTERASE, ...
Authors:Colletier, J.P, Fournier, D, Greenblatt, H.M, Sussman, J.L, Zaccai, G, Silman, I, Weik, M.
Deposit date:2005-10-27
Release date:2006-06-14
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insights Into Substrate Traffic and Inhibition in Acetylcholinesterase.
Embo J., 25, 2006
4W7Y
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BU of 4w7y by Molmil
Dimeric BAP29 vDED with disulfide bonds in crystal contacts
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, B-cell receptor-associated protein 29
Authors:Quistgaard, E.M.
Deposit date:2014-08-22
Release date:2014-10-29
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A disulfide polymerized protein crystal.
Chem.Commun.(Camb.), 50, 2014
4W8I
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BU of 4w8i by Molmil
Crystal structure of LpSPL/Lpp2128, Legionella pneumophila sphingosine-1 phosphate lyase
Descriptor: Probable sphingosine-1-phosphate lyase
Authors:Stogios, P.J, Daniels, C, Skarina, T, Cuff, M, Di Leo, R, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2014-08-24
Release date:2014-11-05
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy.
Proc.Natl.Acad.Sci.USA, 113, 2016
4W8T
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BU of 4w8t by Molmil
Crystal structure of truncated hemolysin A Q125S from P. mirabilis at 1.5 Angstroms resolution
Descriptor: Hemolysin
Authors:Novak, W.R.P, Glasgow, E, Thompson, J.R, Weaver, T.M.
Deposit date:2014-08-26
Release date:2015-10-07
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.539 Å)
Cite:Crystal structure of truncated hemolysin A Q125S from P. mirabilis at 1.5 Angstroms resolution
To Be Published
4W8Z
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BU of 4w8z by Molmil
Crystal structure of Cmr1 from Pyrococcus furiosus (apo form)
Descriptor: CRISPR system Cmr subunit Cmr1-1
Authors:Benda, C, Ebert, J, Baumgaertner, M, Conti, E.
Deposit date:2014-08-26
Release date:2014-10-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4.
Mol.Cell, 56, 2014
2BER
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BU of 2ber by Molmil
Y370G Active Site Mutant of the Sialidase from Micromonospora viridifaciens in complex with beta-Neu5Ac (sialic acid).
Descriptor: BACTERIAL SIALIDASE, N-acetyl-beta-neuraminic acid, SODIUM ION
Authors:Newstead, S, Watson, J.N, Bennet, A.J, Taylor, G.L.
Deposit date:2004-11-30
Release date:2005-04-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and Mechanism of Action of an Inverting Mutant Sialidase.
Biochemistry, 44, 2005
2C4H
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BU of 2c4h by Molmil
Torpedo californica acetylcholinesterase in complex with 500mM acetylthiocholine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ACETYL GROUP, ...
Authors:Colletier, J.P, Fournier, D, Greenblatt, H.M, Sussman, J.L, Zaccai, G, Silman, I, Weik, M.
Deposit date:2005-10-19
Release date:2006-06-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural insights into substrate traffic and inhibition in acetylcholinesterase.
EMBO J., 25, 2006
4WA8
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BU of 4wa8 by Molmil
Methanopyrus Kandleri FEN-1 nuclease
Descriptor: CHLORIDE ION, Flap endonuclease 1
Authors:Shah, S, Dunten, P, Horton, N.C.
Deposit date:2014-08-28
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and specificity of FEN-1 from Methanopyrus kandleri.
Proteins, 83, 2015
6CJ9
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BU of 6cj9 by Molmil
Crystal structure of lectin from Dioclea lasiophylla seeds (DlyL) complexed with X-Man
Descriptor: 5-bromo-4-chloro-1H-indol-3-yl alpha-D-mannopyranoside, CALCIUM ION, Lectin, ...
Authors:Pinto-Junior, V.R, Santiago, M.Q, Osterne, V.J.S, Araripe, D.A, Neco, A.H.B, Silva-Filho, J.C, Leal, R.B, Rocha, C.R.C, Nascimento, K.S, Cavada, B.S.
Deposit date:2018-02-26
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of DlyL, a mannose-specific lectin from Dioclea lasiophylla Mart. Ex Benth seeds that display cytotoxic effects against C6 glioma cells.
Int. J. Biol. Macromol., 114, 2018
4WB0
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BU of 4wb0 by Molmil
Crystal structure of the broad specificity aminotransferase from Leishmania mexicana
Descriptor: Broad specificity aminotransferase, CACODYLATE ION
Authors:Wen, J, Nowicki, C, Blankenfeldt, W.
Deposit date:2014-09-02
Release date:2015-09-09
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural basis for the relaxed substrate selectivity of Leishmania mexicana broad specificity aminotransferase.
Mol.Biochem.Parasitol., 202, 2015
2BJJ
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BU of 2bjj by Molmil
Structure of recombinant human lactoferrin produced in the milk of transgenic cows
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
Authors:Thomassen, E.A.J, Van Veen, H.A, Van Berkel, P.H.C, Nuijens, J.H, Abrahams, J.P.
Deposit date:2005-02-03
Release date:2005-08-01
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Protein Structure of Recombinant Human Lactoferrin Produced in the Milk of Transgenic Cows Closely Matches the Structure of Human Milk-Derived Lactoferrin
Transgenic Res., 14, 2005
9D77
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BU of 9d77 by Molmil
Crystal form of Netrin-1 mimics nanotubes
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Meier, M, Krahn, N.J, McDougall, M.D, Rafiei, F, Koch, M, Stetefeld, J.
Deposit date:2024-08-16
Release date:2024-10-09
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Mechanistic insights in the higher-order protein assemblies of netrin-1
To Be Published

243531

数据于2025-10-22公开中

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