Summary Structural details Experimental details Functional details Sequence Neighbor Downloads

4V1W

3D structure of horse spleen apoferritin determined by electron cryomicroscopy

> Summary

Summary for 4V1W

EMDB information	EMD-2788
Descriptor	FERRITIN LIGHT CHAIN (1 entity in total)
Functional Keywords	storage protein, iron storage, iron transport, ferritins, apoferritins, horses, metals, spleen
Biological source	EQUUS CABALLUS (HORSE)
Total number of polymer chains	24
Total molecular weight	476938.27
Authors	Russo, C.J.,Passmore, L.A. (deposition date: 2014-10-02, release date: 2014-12-10, Last modification date: 2017-08-02)
Primary citation	Russo, C.J.,Passmore, L.A. Electron Microscopy. Ultrastable Gold Substrates for Electron Cryomicroscopy. Science, 346:1377-, 2014 PubMed: 25504723 (PDB entries with the same primary citation) DOI: 10.1126/SCIENCE.1259530 Import into Mendeley
Experimental method	ELECTRON MICROSCOPY (4.7 Å)

Structure validation

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More Asymmetric unit images

Molmil generated image of 4v1w — no rotation

> Structural details

Entity

Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
A, B, C, D, E...	FERRITIN LIGHT CHAIN	polymer	174	19872.4	24	UniProt (P02791) Pfam (PF00210)	EQUUS CABALLUS (HORSE)@PDBj	FERRITIN L SUBUNIT

Sequence viewer

Contents of the asymmetric unit

Polymers	Number of chains	24
Polymers	Total molecular weight	476938.3
Non-Polymers*	Number of molecules	0
Non-Polymers*	Total molecular weight	0.0
All*	Total molecular weight	476938.3

*Water molecules are not included.

> Experimental details

Refinement Statistics

Experimental method:

ELECTRON MICROSCOPY (4.7 Å)

Cell axes	1.000	1.000	1.000
Cell angles	90.00	90.00	90.00
Spacegroup	P 1
Resolution limits	- 4.70
the highest resolution shell value	-

Data Collection Statistics

Resolution limits	-
the highest resolution shell value	-

Crystallization Conditions

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Crystallization Reagents in Literatures*

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Annotated Information is extracted from Literature Info*

> Functional details

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0008043	cellular_component	intracellular ferritin complex
A	0008199	molecular_function	ferric iron binding
A	0005506	molecular_function	iron ion binding
A	0006880	biological_process	intracellular sequestering of iron ion
A	0006826	biological_process	iron ion transport
B	0005737	cellular_component	cytoplasm
B	0008043	cellular_component	intracellular ferritin complex
B	0008199	molecular_function	ferric iron binding
B	0005506	molecular_function	iron ion binding
B	0006880	biological_process	intracellular sequestering of iron ion
B	0006826	biological_process	iron ion transport
C	0005737	cellular_component	cytoplasm
C	0008043	cellular_component	intracellular ferritin complex
C	0008199	molecular_function	ferric iron binding
C	0005506	molecular_function	iron ion binding
C	0006880	biological_process	intracellular sequestering of iron ion
C	0006826	biological_process	iron ion transport
D	0005737	cellular_component	cytoplasm
D	0008043	cellular_component	intracellular ferritin complex
D	0008199	molecular_function	ferric iron binding
D	0005506	molecular_function	iron ion binding
D	0006880	biological_process	intracellular sequestering of iron ion
D	0006826	biological_process	iron ion transport
E	0005737	cellular_component	cytoplasm
E	0008043	cellular_component	intracellular ferritin complex
E	0008199	molecular_function	ferric iron binding
E	0005506	molecular_function	iron ion binding
E	0006880	biological_process	intracellular sequestering of iron ion
E	0006826	biological_process	iron ion transport
F	0005737	cellular_component	cytoplasm
F	0008043	cellular_component	intracellular ferritin complex
F	0008199	molecular_function	ferric iron binding
F	0005506	molecular_function	iron ion binding
F	0006880	biological_process	intracellular sequestering of iron ion
F	0006826	biological_process	iron ion transport
G	0005737	cellular_component	cytoplasm
G	0008043	cellular_component	intracellular ferritin complex
G	0008199	molecular_function	ferric iron binding
G	0005506	molecular_function	iron ion binding
G	0006880	biological_process	intracellular sequestering of iron ion
G	0006826	biological_process	iron ion transport
H	0005737	cellular_component	cytoplasm
H	0008043	cellular_component	intracellular ferritin complex
H	0008199	molecular_function	ferric iron binding
H	0005506	molecular_function	iron ion binding
H	0006880	biological_process	intracellular sequestering of iron ion
H	0006826	biological_process	iron ion transport
I	0005737	cellular_component	cytoplasm
I	0008043	cellular_component	intracellular ferritin complex
I	0008199	molecular_function	ferric iron binding
I	0005506	molecular_function	iron ion binding
I	0006880	biological_process	intracellular sequestering of iron ion
I	0006826	biological_process	iron ion transport
J	0005737	cellular_component	cytoplasm
J	0008043	cellular_component	intracellular ferritin complex
J	0008199	molecular_function	ferric iron binding
J	0005506	molecular_function	iron ion binding
J	0006880	biological_process	intracellular sequestering of iron ion
J	0006826	biological_process	iron ion transport
K	0005737	cellular_component	cytoplasm
K	0008043	cellular_component	intracellular ferritin complex
K	0008199	molecular_function	ferric iron binding
K	0005506	molecular_function	iron ion binding
K	0006880	biological_process	intracellular sequestering of iron ion
K	0006826	biological_process	iron ion transport
L	0005737	cellular_component	cytoplasm
L	0008043	cellular_component	intracellular ferritin complex
L	0008199	molecular_function	ferric iron binding
L	0005506	molecular_function	iron ion binding
L	0006880	biological_process	intracellular sequestering of iron ion
L	0006826	biological_process	iron ion transport
M	0005737	cellular_component	cytoplasm
M	0008043	cellular_component	intracellular ferritin complex
M	0008199	molecular_function	ferric iron binding
M	0005506	molecular_function	iron ion binding
M	0006880	biological_process	intracellular sequestering of iron ion
M	0006826	biological_process	iron ion transport
N	0005737	cellular_component	cytoplasm
N	0008043	cellular_component	intracellular ferritin complex
N	0008199	molecular_function	ferric iron binding
N	0005506	molecular_function	iron ion binding
N	0006880	biological_process	intracellular sequestering of iron ion
N	0006826	biological_process	iron ion transport
O	0005737	cellular_component	cytoplasm
O	0008043	cellular_component	intracellular ferritin complex
O	0008199	molecular_function	ferric iron binding
O	0005506	molecular_function	iron ion binding
O	0006880	biological_process	intracellular sequestering of iron ion
O	0006826	biological_process	iron ion transport
P	0005737	cellular_component	cytoplasm
P	0008043	cellular_component	intracellular ferritin complex
P	0008199	molecular_function	ferric iron binding
P	0005506	molecular_function	iron ion binding
P	0006880	biological_process	intracellular sequestering of iron ion
P	0006826	biological_process	iron ion transport
Q	0005737	cellular_component	cytoplasm
Q	0008043	cellular_component	intracellular ferritin complex
Q	0008199	molecular_function	ferric iron binding
Q	0005506	molecular_function	iron ion binding
Q	0006880	biological_process	intracellular sequestering of iron ion
Q	0006826	biological_process	iron ion transport
R	0005737	cellular_component	cytoplasm
R	0008043	cellular_component	intracellular ferritin complex
R	0008199	molecular_function	ferric iron binding
R	0005506	molecular_function	iron ion binding
R	0006880	biological_process	intracellular sequestering of iron ion
R	0006826	biological_process	iron ion transport
S	0005737	cellular_component	cytoplasm
S	0008043	cellular_component	intracellular ferritin complex
S	0008199	molecular_function	ferric iron binding
S	0005506	molecular_function	iron ion binding
S	0006880	biological_process	intracellular sequestering of iron ion
S	0006826	biological_process	iron ion transport
T	0005737	cellular_component	cytoplasm
T	0008043	cellular_component	intracellular ferritin complex
T	0008199	molecular_function	ferric iron binding
T	0005506	molecular_function	iron ion binding
T	0006880	biological_process	intracellular sequestering of iron ion
T	0006826	biological_process	iron ion transport
U	0005737	cellular_component	cytoplasm
U	0008043	cellular_component	intracellular ferritin complex
U	0008199	molecular_function	ferric iron binding
U	0005506	molecular_function	iron ion binding
U	0006880	biological_process	intracellular sequestering of iron ion
U	0006826	biological_process	iron ion transport
V	0005737	cellular_component	cytoplasm
V	0008043	cellular_component	intracellular ferritin complex
V	0008199	molecular_function	ferric iron binding
V	0005506	molecular_function	iron ion binding
V	0006880	biological_process	intracellular sequestering of iron ion
V	0006826	biological_process	iron ion transport
W	0005737	cellular_component	cytoplasm
W	0008043	cellular_component	intracellular ferritin complex
W	0008199	molecular_function	ferric iron binding
W	0005506	molecular_function	iron ion binding
W	0006880	biological_process	intracellular sequestering of iron ion
W	0006826	biological_process	iron ion transport
X	0005737	cellular_component	cytoplasm
X	0008043	cellular_component	intracellular ferritin complex
X	0008199	molecular_function	ferric iron binding
X	0005506	molecular_function	iron ion binding
X	0006880	biological_process	intracellular sequestering of iron ion
X	0006826	biological_process	iron ion transport

Functional Information from PDB Data

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Functional Information from PDB atom coordinates for the "HETATM" binding sites

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Functional Information from PROSITE/UniProt

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Functional Information from SwissProt/UniProt

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SWS_FT_FI1