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5WF0
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70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fislage, M, Frank, J.
Deposit date:2017-07-11
Release date:2018-05-02
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
1WAW
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BU of 1waw by Molmil
Specificity and affinity of natural product cyclopentapeptide inhibitor Argadin against human chitinase
Descriptor: ARGADIN, CHITOTRIOSIDASE 1, GLYCEROL, ...
Authors:Rao, F.V, Houston, D.R, Boot, R.G, Aerts, J.M.F.G, Hodkinson, M, Adams, D.J, Shiomi, K, Omura, S, van Aalten, D.M.F.
Deposit date:2004-10-28
Release date:2005-01-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases
Chem.Biol., 12, 2005
1VYF
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BU of 1vyf by Molmil
schistosoma mansoni fatty acid binding protein in complex with oleic acid
Descriptor: 14 KDA FATTY ACID BINDING PROTEIN, OLEIC ACID
Authors:Angelucci, F, Johnson, K.A, Baiocco, P, Miele, A.E, Bellelli, A.
Deposit date:2004-04-29
Release date:2004-09-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Schistosoma Mansoni Fatty Acid Binding Protein: Specificity and Functional Control as Revealed by Crystallographic Structure
Biochemistry, 43, 2004
5WSZ
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BU of 5wsz by Molmil
Crystal structure of a lytic polysaccharide monooxygenase,BtLPMO10A, from Bacillus thuringiensis
Descriptor: COPPER (II) ION, LpmO10A
Authors:Zhao, Y, Zhang, H, Yin, H.
Deposit date:2016-12-08
Release date:2017-02-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.565 Å)
Cite:Crystal structure of a lytic polysaccharide monooxygenase,BtLPMO10A, from Bacillus thuringiensis
To Be Published
1VZ2
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PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN, Y73C/V427C/C255T MUTANT
Descriptor: GLYCEROL, PROLYL ENDOPEPTIDASE
Authors:Rea, D, Fulop, V.
Deposit date:2004-05-14
Release date:2004-07-01
Last modified:2025-10-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Concerted Structural Changes in the Peptidase and the Propeller Domains of Prolyl Oligopeptidase are Required for Substrate Binding
J.Mol.Biol., 340, 2004
1W40
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BU of 1w40 by Molmil
T. celer L30e K9A variant
Descriptor: 50S RIBOSOMAL PROTEIN L30E
Authors:Lee, C.F, Lee, K.M, Chan, S.H, Allen, M.D, Bycroft, M, Wong, K.B.
Deposit date:2004-07-22
Release date:2005-04-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Electrostatic Interactions Contribute to Reduced Heat Capacity Change of Unfolding in a Thermophilic Ribosomal Protein L30E
J.Mol.Biol., 348, 2005
5WTT
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BU of 5wtt by Molmil
Structure of the 093G9 Fab in complex with the epitope peptide
Descriptor: Epitope peptide of Cyr61, Heavy chain of 093G9 Fab, Light chain of 093G9 Fab
Authors:Zhong, C, Hu, K, Shen, J, Ding, J.
Deposit date:2016-12-14
Release date:2017-12-20
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis for the recognition of CCN1 by monoclonal antibody 093G9.
J. Mol. Recognit., 30, 2017
1VZW
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Crystal structure of the bifunctional protein Pria
Descriptor: GLYCEROL, PHOSPHORIBOSYL ISOMERASE A, SULFATE ION
Authors:Kuper, J, Wilmanns, M.
Deposit date:2004-05-27
Release date:2005-01-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Two-Fold Repeated (Beta-Alpha)(4) Half-Barrels May Provide a Molecular Tool for Dual Substrate Specificity
Embo Rep., 6, 2005
5WUW
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BU of 5wuw by Molmil
Serratia marcescens short-chain dehydrogenase/reductase F98L/F202L mutant
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase
Authors:Liu, J.-S, Tsou, Y, Wang, W.-C.
Deposit date:2016-12-21
Release date:2018-02-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-guided design of Serratia marcescens short-chain dehydrogenase/reductase for stereoselective synthesis of (R)-phenylephrine.
Sci Rep, 8, 2018
1W5B
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BU of 1w5b by Molmil
FtsZ dimer, GTP soak (M. jannaschii)
Descriptor: CELL DIVISION PROTEIN FTSZ HOMOLOG 1, GUANOSINE-5'-TRIPHOSPHATE
Authors:Oliva, M.A, Cordell, S.C, Lowe, J.
Deposit date:2004-08-06
Release date:2004-12-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights Into Ftsz Protofilament Formation
Nat.Struct.Mol.Biol., 11, 2004
5W7I
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BU of 5w7i by Molmil
X-ray structure of ankyrin repeat domain of DHHC17 in complex with Snap25b peptide
Descriptor: Palmitoyltransferase ZDHHC17, Snap25b-111-120
Authors:Verardi, R, Kim, J.-S, Ghirlando, R, Banerjee, A.
Deposit date:2017-06-20
Release date:2017-08-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Structural Basis for Substrate Recognition by the Ankyrin Repeat Domain of Human DHHC17 Palmitoyltransferase.
Structure, 25, 2017
1W2G
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BU of 1w2g by Molmil
Crystal Structure Of Mycobacterium Tuberculosis Thymidylate Kinase Complexed With Deoxythymidine (dT) (2.1 A Resolution)
Descriptor: ACETATE ION, THYMIDINE, THYMIDYLATE KINASE TMK
Authors:Fioravanti, E, Adam, V, Munier-Lehmann, H, Bourgeois, D.
Deposit date:2004-07-06
Release date:2005-01-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Crystal Structure of Mycobacterium Tuberculosis Thymidylate Kinase in Complex with 3'-Azidodeoxythymidine Monophosphate Suggests a Mechanism for Competitive Inhibition
Biochemistry, 44, 2005
1W1L
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BU of 1w1l by Molmil
STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE: Phe454Tyr Mutant
Descriptor: 2-methoxy-4-[(1E)-prop-1-en-1-yl]phenol, FLAVIN-ADENINE DINUCLEOTIDE, VANILLYL-ALCOHOL OXIDASE
Authors:Van Den Heuvel, R.H.
Deposit date:2004-06-22
Release date:2004-07-02
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Laboratory-Evolved Vanillyl-Alcohol Oxidase Produces Natural Vanillin
J.Biol.Chem., 279, 2004
1W15
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BU of 1w15 by Molmil
rat synaptotagmin 4 C2B domain in the presence of calcium
Descriptor: CALCIUM ION, CHLORIDE ION, SODIUM ION, ...
Authors:Dai, H, Shin, O.-H, Machius, M, Tomchick, D.R, Sudhof, T.C, Rizo, J.
Deposit date:2004-06-16
Release date:2004-08-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural Basis for the Evolutionary Inactivation of Ca2+ Binding to Synaptotagmin 4
Nat.Struct.Mol.Biol., 11, 2004
1W2H
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BU of 1w2h by Molmil
Crystal Structure Of Mycobacterium Tuberculosis Thymidylate Kinase Complexed With Azidothymidine Monophosphate (AZT-MP) (2.0 A Resolution)
Descriptor: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ACETATE ION, THYMIDYLATE KINASE TMK
Authors:Fioravanti, E, Adam, V, Munier-Lehmann, H, Bourgeois, D.
Deposit date:2004-07-06
Release date:2005-01-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of Mycobacterium tuberculosis thymidylate kinase in complex with 3'-azidodeoxythymidine monophosphate suggests a mechanism for competitive inhibition.
Biochemistry, 44, 2005
1W5M
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BU of 1w5m by Molmil
Stepwise introduction of zinc binding site into porphobilinogen synthase of Pseudomonas aeruginosa (mutations A129C and D139C)
Descriptor: CHLORIDE ION, DELTA-AMINOLEVULINIC ACID DEHYDRATASE, FORMIC ACID, ...
Authors:Frere, F, Reents, H, Schubert, W.-D, Heinz, D.W, Jahn, D.
Deposit date:2004-08-09
Release date:2005-01-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W50
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BU of 1w50 by Molmil
Apo Structure of BACE (Beta Secretase)
Descriptor: BETA-SECRETASE 1, IODIDE ION
Authors:Patel, S, Vuillard, L, Cleasby, A, Murray, C.W, Yon, J.
Deposit date:2004-08-04
Release date:2004-09-23
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Apo and Inhibitor Complex Structures of Bace (Beta-Secretase)
J.Mol.Biol., 343, 2004
1W6Q
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BU of 1w6q by Molmil
X-RAY CRYSTAL STRUCTURE OF R111H HUMAN GALECTIN-1
Descriptor: BETA-MERCAPTOETHANOL, GALECTIN-1
Authors:Lopez-Lucendo, M.I.F, Gabius, H.J, Romero, A.
Deposit date:2004-08-21
Release date:2004-10-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Growth-Regulatory Human Galectin-1: Crystallographic Characterisation of the Structural Changes Induced by Single-Site Mutations and Their Impact on the Thermodynamics of Ligand Binding
J.Mol.Biol., 343, 2004
5LUB
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BU of 5lub by Molmil
Crystal structure of human legumain (AEP) in complex with compound 11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-(morpholin-4-yl)-2,1,3-benzoxadiazol-4-amine, ...
Authors:Dall, E, Ye, K, Brandstetter, H.
Deposit date:2016-09-08
Release date:2017-03-29
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease.
Nat Commun, 8, 2017
1VYP
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BU of 1vyp by Molmil
Structure of pentaerythritol tetranitrate reductase W102F mutant and complexed with picric acid
Descriptor: FLAVIN MONONUCLEOTIDE, PENTAERYTHRITOL TETRANITRATE REDUCTASE, PICRIC ACID
Authors:Barna, T, Moody, P.C.E.
Deposit date:2004-05-04
Release date:2004-05-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Atomic Resolution Structures and Solution Behavior of Enzyme-Substrate Complexes of Enterobacter Cloacae Pb2 Pentaerythritol Tetranitrate Reductase: Multiple Conformational States and Implications for the Mechanism of Nitroaromatic Explosive Degradation
J.Biol.Chem., 279, 2004
1VZO
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BU of 1vzo by Molmil
The structure of the N-terminal kinase domain of MSK1 reveals a novel autoinhibitory conformation for a dual kinase protein
Descriptor: BETA-MERCAPTOETHANOL, RIBOSOMAL PROTEIN S6 KINASE ALPHA 5, SULFATE ION
Authors:Smith, K.J, Carter, P.S, Bridges, A, Horrocks, P, Lewis, C, Pettman, G, Clarke, A, Brown, M, Hughes, J, Wilkinson, M, Bax, B, Reith, A.
Deposit date:2004-05-21
Release date:2004-06-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of Msk1 Reveals a Novel Autoinhibitory Conformation for a Dual Kinase Protein
Structure, 12, 2004
7OAN
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BU of 7oan by Molmil
Nanobody C5 bound to Spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Naismith, J.H, Weckener, M.
Deposit date:2021-04-19
Release date:2021-08-11
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19.
Nat Commun, 12, 2021
1W3C
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BU of 1w3c by Molmil
Crystal structure of the Hepatitis C Virus NS3 Protease in complex with a peptidomimetic inhibitor
Descriptor: 3-({(2S)-2-[({(1R)-1-[({(1R)-1-[(R)-CARBOXY(HYDROXY)METHYL]-3,3-DIFLUOROPROPYL}AMINO)CARBONYL]-3-METHYLBUTYL}AMINO)CARB ONYL]-2,3-DIHYDRO-1H-INDOL-2-YL}METHYL)THIOPHENE-2-CARBOXYLIC ACID, 3-({(2S)-2-[({(1S)-1-[({(1S)-1-[(R)-CARBOXY(HYDROXY)METHYL]-3,3-DIFLUOROPROPYL}AMINO)CARBONYL]-3-METHYLBUTYL}AMINO)CARBONYL]-2,3-DIHYDRO-1H-INDOL-2-YL}METHYL)THIOPHENE-2-CARBOXYLIC ACID, NONSTRUCTURAL PROTEIN NS4A (P4), ...
Authors:Di Marco, S, Volpari, C.
Deposit date:2004-07-14
Release date:2004-12-09
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Design and Enzyme-Bound Crystal Structure of Indoline Based Peptidomimetic Inhibitors of Hepatitis C Virus Ns3 Protease
J.Med.Chem., 47, 2004
1W19
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Lumazine Synthase from Mycobacterium tuberculosis bound to 3-(1,3,7- trihydro-9-D-ribityl-2,6,8-purinetrione-7-yl)propane 1-phosphate
Descriptor: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (4S,5S)-1,2-DITHIANE-4,5-DIOL, ...
Authors:Morgunova, E, Meining, W, Illarionov, B, Haase, I, Fischer, M, Cushman, M, Bacher, A, Ladenstein, R.
Deposit date:2004-06-03
Release date:2005-03-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Lumazine Synthase from Mycobacterium Tuberculosis as a Target for Rational Drug Design: Binding Mode of a New Class of Purinetrione Inhibitors(,)
Biochemistry, 44, 2005
1W23
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Crystal structure of phosphoserine aminotransferase from Bacillus alcalophilus
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Dubnovitsky, A, Kapetaniou, E.G, Papageorgiou, A.C.
Deposit date:2004-06-25
Release date:2004-12-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Enzyme Adaptation to Alkaline Ph: Atomic Resolution (1.08 A) Structure of Phosphoserine Aminotransferase from Bacillus Alcalophilus
Protein Sci., 14, 2005

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数据于2025-10-15公开中

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