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8B9A
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BU of 8b9a by Molmil
S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand.
Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
Authors:Jones, M.L, Yeeles, J.T.P.
Deposit date:2022-10-05
Release date:2023-08-09
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
9GEF
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BU of 9gef by Molmil
Experimental localization of metal-binding sites reveals the role of metal ions in the delafloxacin-stabilized Streptococcus pneumoniae topoisomerase IV DNA cleavage complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CHLORIDE ION, ...
Authors:Wang, B, Najmudin, S, Pan, X.-S, Mykhaylyk, V, Orr, C, Wagner, A, Govada, L, Chayen, N.E, Fisher, L.M, Sanderson, M.R.
Deposit date:2024-08-08
Release date:2024-10-16
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Experimental localization of metal-binding sites reveals the role of metal ions in type II DNA topoisomerases.
Proc.Natl.Acad.Sci.USA, 121, 2024
9F6I
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BU of 9f6i by Molmil
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Post-Insertion state)
Descriptor: 2',3'-dideoxyadenosine triphosphate, CALCIUM ION, DNA nascent strand, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6L
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BU of 9f6l by Molmil
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Mismatch Excision state)
Descriptor: CALCIUM ION, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
1FOS
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BU of 1fos by Molmil
TWO HUMAN C-FOS:C-JUN:DNA COMPLEXES
Descriptor: C-JUN PROTO-ONCOGENE PROTEIN, DNA (5'-D(*AP*AP*TP*GP*GP*AP*TP*GP*AP*GP*TP*CP*AP*TP*AP*GP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*TP*CP*CP*TP*AP*TP*GP*AP*CP*TP*CP*AP*TP*CP*CP*AP*T)-3'), ...
Authors:Glover, J.N.M, Harrison, S.C.
Deposit date:1995-03-07
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA.
Nature, 373, 1995
9BDY
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BU of 9bdy by Molmil
AT-centric NF-kappaB RelA binding DNA
Descriptor: ACETATE ION, DNA (5'-D(*CP*GP*GP*AP*AP*TP*TP*TP*CP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*G)-3'), ...
Authors:Biswas, T, Shahabi, S, Tsodikov, O.V, Ghosh, G.
Deposit date:2024-04-13
Release date:2024-08-07
Last modified:2024-08-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA.
Proc.Natl.Acad.Sci.USA, 121, 2024
8VAR
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BU of 8var by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA2 conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8VAL
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BU of 8val by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Open-DNAp/t conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8VAQ
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BU of 8vaq by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA1 conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
3N4M
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BU of 3n4m by Molmil
E. coli RNA polymerase alpha subunit C-terminal domain in complex with CAP and DNA
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DI(HYDROXYETHYL)ETHER, ...
Authors:Lara-Gonzalez, S, Birktoft, J.J, Lawson, C.L.
Deposit date:2010-05-21
Release date:2011-05-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.987 Å)
Cite:The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element.
Biochemistry, 59, 2020
9BE0
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BU of 9be0 by Molmil
GC-centric NF-kappaB RelA binding DNA
Descriptor: ACETATE ION, DNA (5'-D(*CP*GP*GP*GP*AP*AP*GP*TP*TP*CP*CP*GP*CP*GP*GP*AP*AP*CP*TP*TP*CP*CP*CP*G)-3'), ZINC ION
Authors:Biswas, T, Shahabi, S, Tsodikov, O.V, Ghosh, G.
Deposit date:2024-04-13
Release date:2024-08-07
Last modified:2024-08-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA.
Proc.Natl.Acad.Sci.USA, 121, 2024
3M3Y
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BU of 3m3y by Molmil
RNA polymerase II elongation complex C
Descriptor: DNA (28-MER), DNA (5'-D(*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Zhu, G, Huang, X, Lippard, S.J.
Deposit date:2010-03-10
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M4O
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BU of 3m4o by Molmil
RNA polymerase II elongation complex B
Descriptor: DNA (28-MER), DNA (5'-D(P*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Zhu, G, Huang, X, Lippard, S.J.
Deposit date:2010-03-11
Release date:2010-05-12
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.57 Å)
Cite:X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.
Proc.Natl.Acad.Sci.USA, 107, 2010
9BDZ
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BU of 9bdz by Molmil
TA-centric NF-kappaB RelA binding DNA
Descriptor: ACETATE ION, ZINC ION, double-stranded DNA
Authors:Biswas, T, Shahabi, S, Tsodikov, O.V, Wang, V, Ghosh, G.
Deposit date:2024-04-13
Release date:2024-08-07
Last modified:2024-08-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA.
Proc.Natl.Acad.Sci.USA, 121, 2024
8YHA
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BU of 8yha by Molmil
Type I-EHNH Cascade-ssDNA complex
Descriptor: 61-nt crRNA, CRISPR system Cascade subunit CasC, CRISPR system Cascade subunit CasD, ...
Authors:Li, Z.
Deposit date:2024-02-27
Release date:2024-07-31
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems.
Mol.Cell, 84, 2024
9BE1
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BU of 9be1 by Molmil
CG-centric NF-kappaB RelA binding DNA
Descriptor: ACETATE ION, DNA (5'-D(*CP*GP*GP*GP*AP*AP*TP*TP*TP*CP*CP*GP*CP*GP*GP*AP*AP*AP*TP*TP*CP*CP*CP*G)-3'), ZINC ION
Authors:Biswas, T, Shahabi, S, Tsodikov, O.V, Wang, V, Ghosh, G.
Deposit date:2024-04-13
Release date:2024-08-07
Last modified:2024-08-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA.
Proc.Natl.Acad.Sci.USA, 121, 2024
9C6Q
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BU of 9c6q by Molmil
Structure of V. cholerae monomeric DdmD bound with ssDNA
Descriptor: Helicase/UvrB N-terminal domain-containing protein, ssDNA
Authors:Shen, Z.F, Yang, X.Y, Fu, T.M.
Deposit date:2024-06-08
Release date:2024-08-21
Last modified:2024-10-02
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:DdmDE eliminates plasmid invasion by DNA-guided DNA targeting.
Cell, 187, 2024
9BF5
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BU of 9bf5 by Molmil
Structure of V. cholerae DdmD in complex with ssDNA
Descriptor: Helicase/UvrB N-terminal domain-containing protein, ssDNA1, ssDNA2
Authors:Shen, Z.F, Yang, X.Y, Fu, T.M.
Deposit date:2024-04-16
Release date:2024-09-04
Last modified:2024-10-02
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:DdmDE eliminates plasmid invasion by DNA-guided DNA targeting.
Cell, 187, 2024
6HV9
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BU of 6hv9 by Molmil
S. cerevisiae CMG-Pol epsilon-DNA
Descriptor: Cell division control protein 45, DNA (5'-D(*GP*CP*AP*GP*CP*CP*AP*CP*GP*CP*TP*GP*GP*CP*CP*GP*TP*TP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*AP*AP*CP*GP*GP*CP*CP*AP*GP*CP*GP*TP*GP*GP*CP*TP*GP*C)-3'), ...
Authors:Abid Ali, F, Purkiss, A.G, Cheung, A, Costa, A.
Deposit date:2018-10-10
Release date:2018-12-12
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (4.98 Å)
Cite:Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome.
Nat Commun, 9, 2018
4KFC
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BU of 4kfc by Molmil
Crystal structure of a hyperactive mutant of response regulator KdpE complexed to its promoter DNA
Descriptor: KDP operon transcriptional regulatory protein KdpE, Promoter DNA
Authors:Kumar, S, Narayanan, A, Yernool, D.A.
Deposit date:2013-04-26
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:An asymmetric heterodomain interface stabilizes a response regulator-DNA complex.
Nat Commun, 5, 2014
3E00
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BU of 3e00 by Molmil
Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with GW9662, 9-cis Retinoic Acid and NCOA2 Peptide
Descriptor: (9cis)-retinoic acid, 2-chloro-5-nitro-N-phenylbenzamide, DNA (5'-D(*DCP*DAP*DAP*DAP*DCP*DTP*DAP*DGP*DGP*DTP*DCP*DAP*DAP*DAP*DGP*DGP*DTP*DCP*DAP*DG)-3'), ...
Authors:Chandra, V, Huang, P, Hamuro, Y, Raghuram, S, Wang, Y, Burris, T.P, Rastinejad, F.
Deposit date:2008-07-30
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA.
Nature, 456, 2008
3DZY
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BU of 3dzy by Molmil
Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with Rosiglitazone, 9-cis Retinoic Acid and NCOA2 Peptide
Descriptor: (9cis)-retinoic acid, 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), ...
Authors:Chandra, V, Huang, P, Hamuro, Y, Raghuram, S, Wang, Y, Burris, T.P, Rastinejad, F.
Deposit date:2008-07-30
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA.
Nature, 456, 2008
4KNY
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BU of 4kny by Molmil
Crystal structure of the response regulator KdpE complexed to DNA in an active-like conformation
Descriptor: KDP operon transcriptional regulatory protein KdpE, Promoter DNA
Authors:Kumar, S, Narayanan, A, Yernool, D.A.
Deposit date:2013-05-10
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.945 Å)
Cite:An asymmetric heterodomain interface stabilizes a response regulator-DNA complex.
Nat Commun, 5, 2014
3DZU
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BU of 3dzu by Molmil
Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with BVT.13, 9-cis Retinoic Acid and NCOA2 Peptide
Descriptor: (9cis)-retinoic acid, 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID, DNA (5'-D(*DCP*DAP*DAP*DAP*DCP*DTP*DAP*DGP*DGP*DTP*DCP*DAP*DAP*DAP*DGP*DGP*DTP*DCP*DAP*DG)-3'), ...
Authors:Chandra, V, Huang, P, Hamuro, Y, Raghuram, S, Wang, Y, Burris, T.P, Rastinejad, F.
Deposit date:2008-07-30
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA.
Nature, 456, 2008
5JLW
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BU of 5jlw by Molmil
AntpHD with 15bp DNA duplex R-monothioated at Cytidine-8
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*(C7R)P*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ...
Authors:White, M.A, Zandarashvili, L, Iwahara, J, Nguyen, D.
Deposit date:2016-04-27
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.088 Å)
Cite:Stereospecific Effects of Oxygen-to-Sulfur Substitution in DNA Phosphate on Ion Pair Dynamics and Protein-DNA Affinity.
Chembiochem, 17, 2016

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数据于2024-11-06公开中

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