5J1P
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5IZE
| Hantaan virus L protein cap-snatching endonuclease | Descriptor: | MANGANESE (III) ION, RNA-directed RNA polymerase L | Authors: | Reguera, J, Cusack, S. | Deposit date: | 2016-03-25 | Release date: | 2016-06-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases. Plos Pathog., 12, 2016
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3IYD
| Three-dimensional EM structure of an intact activator-dependent transcription initiation complex | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DNA (98-MER), ... | Authors: | Hudson, B.P, Quispe, J, Lara, S, Kim, Y, Berman, H, Arnold, E, Ebright, R.H, Lawson, C.L. | Deposit date: | 2009-08-01 | Release date: | 2009-11-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (19.799999 Å) | Cite: | Three-dimensional EM structure of an intact activator-dependent transcription initiation complex Proc.Natl.Acad.Sci.USA, 106, 2009
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4WC1
| Structure of tRNA-processing enzyme with CTP | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, Poly A polymerase | Authors: | Yamashita, S, Tomita, K. | Deposit date: | 2014-09-04 | Release date: | 2015-04-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme. Structure, 23, 2015
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7ABH
| Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) | Descriptor: | Cell division cycle 5-like protein, DNA/RNA-binding protein KIN17, MINX M3 pre-mRNA, ... | Authors: | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | Deposit date: | 2020-09-07 | Release date: | 2020-12-09 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
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6P1H
| Cryo-EM Structure of DNA Polymerase Delta Holoenzyme | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ... | Authors: | Jain, R, Rice, W, Aggarwal, A.K. | Deposit date: | 2019-05-19 | Release date: | 2019-10-02 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure and dynamics of eukaryotic DNA polymerase delta holoenzyme. Nat.Struct.Mol.Biol., 26, 2019
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4FVM
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8D6J
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4XJN
| Structure of the parainfluenza virus 5 nucleocapsid-RNA complex: an insight into paramyxovirus polymerase activity | Descriptor: | LEAD (II) ION, Nucleocapsid, RNA (78-MER) | Authors: | Alayyoubi, M, Leser, G.P, Kors, C.A, Lamb, R.A. | Deposit date: | 2015-01-08 | Release date: | 2015-03-18 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Structure of the paramyxovirus parainfluenza virus 5 nucleoprotein-RNA complex. Proc.Natl.Acad.Sci.USA, 112, 2015
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7ELL
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7ABF
| Human pre-Bact-1 spliceosome core structure | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | Deposit date: | 2020-09-07 | Release date: | 2020-12-09 | Last modified: | 2020-12-30 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
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4EQK
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3RTX
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1HVU
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7OWF
| KlenTaq DNA polymerase in a ternary complex with primer/template and the fluorescent nucleotide analog BFdUTP | Descriptor: | DNA polymerase I, thermostable, GLYCEROL, ... | Authors: | Betz, K, Srivatsan, S.G. | Deposit date: | 2021-06-18 | Release date: | 2022-06-29 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Microenvironment-Sensitive Fluorescent Nucleotide Probes from Benzofuran, Benzothiophene, and Selenophene as Substrates for DNA Polymerases. J.Am.Chem.Soc., 144, 2022
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1QHT
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7ENJ
| Human Mediator (deletion of MED1-IDR) in a Tail-bent conformation (MED-B) | Descriptor: | Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, ... | Authors: | Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y. | Deposit date: | 2021-04-17 | Release date: | 2021-05-19 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
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6ZOL
| SARS-CoV-2-Nsp1-40S complex, focused on head | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ... | Authors: | Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M.L, Thiel, V, Muehlemann, O, Ban, N. | Deposit date: | 2020-07-07 | Release date: | 2020-07-22 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat.Struct.Mol.Biol., 27, 2020
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7EMF
| Human Mediator (deletion of MED1-IDR) in a Tail-extended conformation | Descriptor: | Isoform 2 of Mediator of RNA polymerase II transcription subunit 16, Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, ... | Authors: | Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y. | Deposit date: | 2021-04-13 | Release date: | 2021-05-05 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
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1NJX
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1NJW
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4ENF
| Crystal structure of the cap-binding domain of polymerase basic protein 2 from influenza virus A/Puerto Rico/8/34(h1n1) | Descriptor: | 1,4-BUTANEDIOL, NITRATE ION, Polymerase basic protein 2 | Authors: | Meng, G, Liu, Y, Zheng, X. | Deposit date: | 2012-04-13 | Release date: | 2013-03-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Structural and functional characterization of K339T substitution identified in the PB2 subunit cap-binding pocket of influenza A virus J.Biol.Chem., 288, 2013
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4FYD
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3P87
| Structure of human PCNA bound to RNASEH2B PIP box peptide | Descriptor: | Proliferating cell nuclear antigen, Ribonuclease H2 subunit B | Authors: | Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P. | Deposit date: | 2010-10-13 | Release date: | 2011-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | PCNA directs type 2 RNase H activity on DNA replication and repair substrates. Nucleic Acids Res., 39, 2011
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4WLW
| CRYSTAL STRUCTURE OF THE AG(I) (ACTIVATOR) FORM OF E. COLI CUER, A COPPER EFFLUX REGULATOR, BOUND TO COPA PROMOTER DNA | Descriptor: | DNA NON-TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP *DTP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DGP*DCP*DTP*DGP*DGP*DAP *DAP*DGP*DGP*DTP*DC)-3, DNA TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP*DTP *DTP*DCP*DCP*DAP*DGP*DCP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DAP *DGP*DGP*DTP*DC)-3, HTH-type transcriptional regulator CueR, ... | Authors: | Philips, S.J, Canalizo-Hernandez, M, Mondragon, A, O'Halloran, T.V. | Deposit date: | 2014-10-08 | Release date: | 2015-09-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter. Science, 349, 2015
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