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1XT5
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Crystal Structure of VCBP3, domain 1, from Branchiostoma floridae
Descriptor: SULFATE ION, variable region-containing chitin-binding protein 3
Authors:Hernandez Prada, J.A, Haire, R.N, Cannon, J.P, Allaire, M, Jakoncic, J, Stojanoff, V, Litman, G.W, Ostrov, D.A.
Deposit date:2004-10-21
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Ancient evolutionary origin of diversified variable regions demonstrated by crystal structures of an immune-type receptor in amphioxus.
Nat.Immunol., 7, 2006
1YNL
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Identification of Key residues of the NC6.8 Fab antibody fragment binding to synthetic sweeterners: Crystal structure of NC6.8 co-crystalized with high potency sweetener compound SC45647
Descriptor: 2-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-ETHANESULFONIC ACID, Ig gamma heavy chain, Ig gamma light chain
Authors:Gokulan, K, Khare, S, Ronning, D.R, Linthicum, S.D, Sacchettini, J.C, Rupp, B.
Deposit date:2005-01-24
Release date:2005-08-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Cocrystal Structures of NC6.8 Fab Identify Key Interactions for High Potency Sweetener Recognition: Implications for the Design of Synthetic Sweeteners
Biochemistry, 44, 2005
1YNK
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Identification of Key residues of the NC6.8 Fab antibody fragment binding to synthetic sweeteners: Crystal structure of NC6.8 co-crystalized with high potency sweetener compound SC45647
Descriptor: 2-[((R)-{[4-(AMINOMETHYL)PHENYL]AMINO}{[(1R)-1-PHENYLETHYL]AMINO}METHYL)AMINO]ETHANE-1,1-DIOL, Ig gamma heavy chain, immunoglobulin kappa light chain
Authors:Gokulan, K, Khare, S, Ronning, D.R, Linthicum, S.D, Sacchettini, J.C, Rupp, B.
Deposit date:2005-01-24
Release date:2005-08-16
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Cocrystal Structures of NC6.8 Fab Identify Key Interactions for High Potency Sweetener Recognition: Implications for the Design of Synthetic Sweeteners
Biochemistry, 44, 2005
2BJM
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BU of 2bjm by Molmil
SPE7:Anthrone Complex
Descriptor: ANTHRONE, IGE SPE7 HEAVY CHAIN, IGE SPE7 LIGHT CHAIN
Authors:James, L.C, Tawfik, D.S.
Deposit date:2005-02-04
Release date:2005-08-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure and Kinetics of a Transient Antibody Binding Intermediate Reveal a Kinetic Discrimination Mechanism in Antigen Recognition
Proc.Natl.Acad.Sci.USA, 102, 2005
1WZ1
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Crystal structure of the Fv fragment complexed with dansyl-lysine
Descriptor: Ig heavy chain, Ig light chain, N~6~-{[5-(DIMETHYLAMINO)-1-NAPHTHYL]SULFONYL}-L-LYSINE
Authors:Nakasako, M, Oka, T, Mashumo, M, Takahashi, H, Shimada, I, Yamaguchi, Y, Kato, K, Arata, Y.
Deposit date:2005-02-21
Release date:2006-01-31
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Conformational dynamics of complementarity-determining region H3 of an anti-dansyl Fv fragment in the presence of its hapten
J.Mol.Biol., 351, 2005
2BNR
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Structural and kinetic basis for heightened immunogenicity of T cell vaccines
Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, SYNTHETIC PEPTIDE, ...
Authors:Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, van der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V.
Deposit date:2005-03-31
Release date:2005-05-23
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines
J.Exp.Med., 201, 2005
2BNQ
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Structural and kinetic basis for heightened immunogenicity of T cell vaccines
Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, SYNTHETIC PEPTIDE, ...
Authors:Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, van der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V.
Deposit date:2005-03-31
Release date:2005-05-23
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines
J.Exp.Med., 201, 2005
1Z9M
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Crystal Structure of Nectin-like molecule-1 protein Domain 1
Descriptor: GAPA225
Authors:Dong, X, Xu, F, Gong, Y, Gao, J, Lin, P, Chen, T, Peng, Y, Qiang, B, Yuan, J, Peng, X, Rao, Z.
Deposit date:2005-04-03
Release date:2006-02-07
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the V Domain of Human Nectin-like Molecule-1/Syncam3/Tsll1/Igsf4b, a Neural Tissue-specific Immunoglobulin-like Cell-Cell Adhesion Molecule
J.Biol.Chem., 281, 2006
2BNU
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Structural and kinetic basis for heightened immunogenicity of T cell vaccines
Descriptor: T-CELL RECEPTOR ALPHA CHAIN C REGION, T-CELL RECEPTOR BETA CHAIN C REGION
Authors:Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, Van Der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V.
Deposit date:2005-04-04
Release date:2005-05-24
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines.
J.Exp.Med., 201, 2005
1ZA6
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The structure of an antitumor CH2-domain-deleted humanized antibody
Descriptor: IGG Heavy chain, IGG Light chain
Authors:Larson, S.B, Day, J.S, Glaser, S, Braslawsky, G, McPherson, A.
Deposit date:2005-04-05
Release date:2005-05-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of an Antitumor C(H)2-domain-deleted Humanized Antibody.
J.Mol.Biol., 348, 2005
1ZAN
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BU of 1zan by Molmil
Crystal structure of anti-NGF AD11 Fab
Descriptor: CHLORIDE ION, Fab AD11 Heavy Chain, Fab AD11 Light Chain
Authors:Covaceuszach, S, Cattaneo, A, Cassetta, A, Lamba, D.
Deposit date:2005-04-06
Release date:2006-04-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody.
J.Mol.Biol., 381, 2008
1ZEA
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BU of 1zea by Molmil
Structure of the anti-cholera toxin antibody Fab fragment TE33 in complex with a D-peptide
Descriptor: CITRIC ACID, monoclonal anti-cholera toxin IGG1 KAPPA antibody, H chain, ...
Authors:Scheerer, P, Krauss, N, Wessner, H, Scholz, C, Otte, L, Seifert, M, Kramer, A, Schneider-Mergener, J, Hoehne, W.
Deposit date:2005-04-18
Release date:2006-04-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of an anti-cholera toxin antibody Fab in complex with an epitope-derived D-peptide: a case of polyspecific recognition.
J.Mol.Recognit., 20, 2007
1ZOX
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BU of 1zox by Molmil
CLM-1 Mouse Myeloid Receptor Extracellular Domain
Descriptor: CLM-1
Authors:Nelson, C.N, Burton, R.L, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
Deposit date:2005-05-15
Release date:2005-05-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the Mouse CLM-1 Ectodomain
To be Published
2COQ
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BU of 2coq by Molmil
Structure of new antigen receptor variable domain from sharks
Descriptor: new antigen receptor variable domain
Authors:Streltsov, V.A, Carmichael, J.A, Nuttall, S.D.
Deposit date:2005-05-18
Release date:2005-10-25
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of a shark IgNAR antibody variable domain and modeling of an early-developmental isotype.
Protein Sci., 14, 2005
1ZVO
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BU of 1zvo by Molmil
Semi-extended solution structure of human myeloma immunoglobulin D determined by constrained X-ray scattering
Descriptor: Immunoglobulin delta heavy chain, myeloma immunoglobulin D lambda
Authors:Sun, Z, Almogren, A, Furtado, P.B, Chowdhury, B, Kerr, M.A, Perkins, S.J.
Deposit date:2005-06-02
Release date:2005-10-25
Last modified:2024-02-14
Method:SOLUTION SCATTERING
Cite:Semi-extended Solution Structure of Human Myeloma Immunoglobulin D Determined by Constrained X-ray Scattering.
J.Mol.Biol., 353, 2005
2A1W
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BU of 2a1w by Molmil
Anti-cocaine antibody 7.5.21, crystal form I
Descriptor: SULFATE ION, immunoglobulin heavy chain, immunoglobulin light chain kappa
Authors:Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A.
Deposit date:2005-06-21
Release date:2005-06-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Flexibility Of Packing: Four Crystal Forms Of An Anti-Cocaine Antibody 7.5.21
To be Published
2BVE
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BU of 2bve by Molmil
Structure of the N-terminal of Sialoadhesin in complex with 2-Phenyl- Prop5Ac
Descriptor: SIALOADHESIN, benzyl 3,5-dideoxy-5-(propanoylamino)-D-glycero-alpha-D-galacto-non-2-ulopyranosidonic acid
Authors:Zaccai, N.R, May, A.P, Robinson, R.C, Burtnick, L.D, Crocker, P, Brossmer, R, Kelm, S, Jones, E.Y.
Deposit date:2005-06-27
Release date:2006-07-19
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic and in Silico Analysis of the Sialoside-Binding Characteristics of the Siglec Sialoadhesin.
J.Mol.Biol., 365, 2007
2A6K
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BU of 2a6k by Molmil
Crystal Structure Analysis of the germline antibody 36-65 Fab in complex with the dodecapeptide SLGDNLTNHNLR
Descriptor: DODECAPEPTIDE: SLGDNLTNHNLR, Germline antibody 36-65 Fab heavy chain, Germline antibody 36-65 Fab light chain
Authors:Sethi, D.K, Agarwal, A, Manivel, V, Rao, K.V, Salunke, D.M.
Deposit date:2005-07-03
Release date:2006-06-13
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Differential epitope positioning within the germline antibody paratope enhances promiscuity in the primary immune response.
Immunity, 24, 2006
2ADF
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BU of 2adf by Molmil
Crystal Structure and Paratope Determination of 82D6A3, an Antithrombotic Antibody Directed Against the von Willebrand factor A3-Domain
Descriptor: 82D6A3 IgG, ACETIC ACID, GLYCEROL, ...
Authors:Staelens, S, Hadders, M.A, Vauterin, S, Platteau, C, Vanhoorelbeke, K, Huizinga, E.G, Deckmyn, H.
Deposit date:2005-07-20
Release date:2005-12-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Paratope determination of the antithrombotic antibody 82D6A3 based on the crystal structure of its complex with the von Willebrand factor A3-domain
J.Biol.Chem., 281, 2006
2BX5
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Is FR1 the antibody's Achillies heel
Descriptor: VD9 VKI LIGHT-CHAIN
Authors:James, L.C.
Deposit date:2005-07-22
Release date:2006-11-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Beta-Edge Interactions in a Pentadecameric Human Antibody Vkappa Domain.
J.Mol.Biol., 367, 2007
2AEQ
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BU of 2aeq by Molmil
An epidemiologically significant epitope of a 1998 influenza virus neuraminidase forms a highly hydrated interface in the NA-antibody complex.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB heavy chain, FAB light chain, ...
Authors:Venkatramani, L, Bochkarev, A, Air, G.M.
Deposit date:2005-07-23
Release date:2005-12-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:An Epidemiologically Significant Epitope of a 1998 Human Influenza Virus Neuraminidase Forms a Highly Hydrated Interface in the NA-Antibody Complex
J.Mol.Biol., 356, 2006
2AEP
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An epidemiologically significant epitope of a 1998 influenza virus neuraminidase forms a highly hydrated interface in the NA-antibody complex.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FAB heavy chain, ...
Authors:Venkatramani, L, Bochkareva, E, Lee, J.T, Gulati, U, Laver, W.G, Bochkarev, A, Air, G.M.
Deposit date:2005-07-23
Release date:2005-12-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An Epidemiologically Significant Epitope of a 1998 Human Influenza Virus Neuraminidase Forms a Highly Hydrated Interface in the NA-Antibody Complex
J.Mol.Biol., 356, 2006
2AGJ
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BU of 2agj by Molmil
Crystal Structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Yvo Fab, Heavy Chain, ...
Authors:Ramsland, P.A, Terzyan, S.S, Cloud, G, Bourne, C.R, Farrugia, W, Tribbick, G, Geysen, H.M, Moomaw, C.R, Slaughter, C.A, Edmundson, A.B.
Deposit date:2005-07-27
Release date:2006-05-02
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody
Biochem.J., 395, 2006
2AI0
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BU of 2ai0 by Molmil
Anti-Cocaine Antibody 7.5.21, Crystal Form III
Descriptor: GLYCEROL, Immunoglobulin Heavy Chain, Immunoglobulin Light Chain kappa, ...
Authors:Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A.
Deposit date:2005-07-28
Release date:2005-08-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Flexibility of Packing: Four Crystal Forms of an Anti-Cocaine Antibody 7.5.21
To be Published
2AJV
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Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with Cocaine
Descriptor: Antibody 7A1 Fab', COCAINE
Authors:Zhu, X, Wilson, I.A.
Deposit date:2005-08-02
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006

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数据于2024-11-13公开中

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