1ZAN
Crystal structure of anti-NGF AD11 Fab
Summary for 1ZAN
Entry DOI | 10.2210/pdb1zan/pdb |
Descriptor | Fab AD11 Light Chain, Fab AD11 Heavy Chain, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | immunoglobulin, fab, immune system |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Secreted: P84751 |
Total number of polymer chains | 2 |
Total formula weight | 46925.48 |
Authors | Covaceuszach, S.,Cattaneo, A.,Cassetta, A.,Lamba, D. (deposition date: 2005-04-06, release date: 2006-04-04, Last modification date: 2023-08-23) |
Primary citation | Covaceuszach, S.,Cassetta, A.,Konarev, P.V.,Gonfloni, S.,Rudolph, R.,Svergun, D.I.,Lamba, D.,Cattaneo, A. Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody. J.Mol.Biol., 381:881-896, 2008 Cited by PubMed: 18635195DOI: 10.1016/j.jmb.2008.06.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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