PDB: 744 resultsInfo pagesStatus searchChemie searchBIRD

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6Q0L	Inferred intermediate I-7 (I-7-1) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab lambda chain, ... Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2019-08-01 Release date: 2019-12-18 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Affinity maturation in a human humoral response to influenza hemagglutinin. Proc.Natl.Acad.Sci.USA, 2019
6Q0I	Inferred intermediate I-7 (I-7-6) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab lambda chain, ... Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2019-08-01 Release date: 2019-12-18 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.702 Å) Cite: Affinity maturation in a human humoral response to influenza hemagglutinin. Proc.Natl.Acad.Sci.USA, 2019
6Q0E	Inferred precursor (UCA) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1) Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Fab heavy chain, Fab lambda light chain, ... Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2019-08-01 Release date: 2019-12-18 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Affinity maturation in a human humoral response to influenza hemagglutinin. Proc.Natl.Acad.Sci.USA, 2019
6Q0O	human antibody H2227 lineage 652 in complex with influenza hemagglutinin head domain of A/Solomon Islands/3/2006(H1N1) Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2019-08-02 Release date: 2019-12-18 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3 Å) Cite: Affinity maturation in a human humoral response to influenza hemagglutinin. Proc.Natl.Acad.Sci.USA, 2019
5Y2M	Crystal structure of a group 2 HA binding antibody AF4H1K1 Fab in complex with the H4N6 duck isolate (H4-CZ/56) hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, a group 2 HA binding antibody AF4H1K1 Fab heavy chain, ... Authors: Xiao, H, Qi, J, Gao, F.G. Deposit date: 2017-07-26 Release date: 2019-02-13 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.8 Å) Cite: An H3-clade neutralizing antibody screened from an H7N9 patient that binds group 2 influenza A hemagglutinins To Be Published
5YT9	Crystal structure of H5 hemagglutinin G228S mutant from A/chicken/Taiwan/0502/2012 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin Authors: Lin, T.H, Lee, M.S, Wu, W.G, Liu, J.S. Deposit date: 2017-11-17 Release date: 2018-11-21 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.766 Å) Cite: crystal structure of H5 hemagglutinin from A/chicken/Taiwan/0502/2012 To Be Published
5Y2L	Crystal structure of a group 2 HA binding antibody AF4H1K1 Fab in complex with the 1968 H3N2 pandemic (H3-AC/68) hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Xiao, H, Qi, J, Gao, F.G. Deposit date: 2017-07-26 Release date: 2019-01-30 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.902 Å) Cite: An H3-clade neutralizing antibody screened from an H7N9 patient that binds group 2 influenza A hemagglutinins To Be Published
5YT8	Crystal structure of H5 hemagglutinin with G228S Q226L mutants from A/chicken/Taiwan/0502/2012 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin Authors: Lin, T.H, Lee, M.S, Wu, W.G, Liu, J.S. Deposit date: 2017-11-17 Release date: 2018-11-21 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.765 Å) Cite: crystal structure of H5 hemagglutinin from A/chicken/Taiwan/0502/2012 To Be Published
5YKC	crystal structure of H5 hemagglutinin from A/chicken/Taiwan/0502/2012 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin Authors: Lin, T.H, Lee, M.S, Wu, W.G. Deposit date: 2017-10-13 Release date: 2018-10-17 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.823 Å) Cite: crystal structure of H5 hemagglutinin from A/chicken/Taiwan/0502/2012 To Be Published
6A67	Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody FLD21.140 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FLD21.140 Heavy Chain, FLD21.140 Light Chain, ... Authors: Wang, P, Zuo, Y, Sun, J, Zhang, L, Wang, X. Deposit date: 2018-06-26 Release date: 2018-08-29 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Complementary recognition of the receptor-binding site of highly pathogenic H5N1 influenza viruses by two human neutralizing antibodies. J. Biol. Chem., 293, 2018
6AOP	Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin L194P mutant apo form Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-08-16 Release date: 2017-10-18 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. PLoS Pathog., 13, 2017
6AOS	Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin L194P mutant in complex with 3'-SLNLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-08-16 Release date: 2017-10-18 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. PLoS Pathog., 13, 2017
6AOQ	Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin apo form Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA2 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-08-16 Release date: 2017-10-18 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.35 Å) Cite: A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. PLoS Pathog., 13, 2017
6AOU	Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin in complex with 3'-SLNLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-08-16 Release date: 2017-10-18 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.75 Å) Cite: A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. PLoS Pathog., 13, 2017
6AOV	Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin in complex with 6'-SLNLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-08-16 Release date: 2017-10-18 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. PLoS Pathog., 13, 2017
6AOR	Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin apo form Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA2 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-08-16 Release date: 2017-10-18 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. PLoS Pathog., 13, 2017
6B3M	The crystal structure of a broadly-reactive human anti-hemagglutinin stalk antibody (70-1F02) in complex with H5 hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 70-1F02 Fab Heavy Chain, ... Authors: Shore, D.A, Yang, H, Stevens, J. Deposit date: 2017-09-22 Release date: 2018-06-13 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (3.92 Å) Cite: Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge. J. Virol., 92, 2018
6A4K	Human antibody 32D6 Fab in complex with H1N1 influenza A virus HA1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... Authors: Lee, C.C, Ko, T.P, Lin, L.L, Wang, A.H.J. Deposit date: 2018-06-20 Release date: 2019-03-27 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.15 Å) Cite: An Effective Neutralizing Antibody Against Influenza Virus H1N1 from Human B Cells. Sci Rep, 9, 2019
6AOT	Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin L194P mutant in complex with 6'-SLNLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-08-16 Release date: 2017-10-18 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.95 Å) Cite: A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. PLoS Pathog., 13, 2017
6BKQ	Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin E190D mutant in complex with 6'-SLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-11-09 Release date: 2018-02-28 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.25 Å) Cite: A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018
6BKO	Crystal structure of the A/Wyoming/3/2003 (H3N2) influenza virus hemagglutinin D190E mutant apo form Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-11-09 Release date: 2018-02-28 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018
6BKS	Crystal structure of the A/Wyoming/3/2003 (H3N2) influenza virus hemagglutinin D190E mutant in complex with 6'-SLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-11-09 Release date: 2018-02-28 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018
6BKM	Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin E190D mutant apo form Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-11-09 Release date: 2018-02-28 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018
6BKT	Crystal structure of the A/Michigan/15/2014 (H3N2) influenza virus hemagglutinin in complex with 6'-SLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-11-09 Release date: 2018-02-28 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018
6D0U	Crystal structure of C05 V110P/A117E mutant bound to H3 influenza hemagglutinin, HA1 subunit Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C05 V110P/A117E mutant, heavy chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2018-04-11 Release date: 2019-01-16 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.25 Å) Cite: Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses. Proc. Natl. Acad. Sci. U.S.A., 116, 2019

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