6BKM

Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin E190D mutant apo form

Summary for 6BKM

• Entry DOI: 10.2210/pdb6bkm/pdb
• Descriptor: Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: influenza, hemagglutinin, receptor, viral protein
• Biological source: Influenza A virus (strain A/Hong Kong/1/1968 H3N2); More
• Total number of polymer chains: 6
• Total formula weight: 171611.87

Authors

Wu, N.C.,Wilson, I.A. (deposition date: 2017-11-09, release date: 2018-02-28, Last modification date: 2023-10-04)

• Primary citation: Wu, N.C.,Thompson, A.J.,Xie, J.,Lin, C.W.,Nycholat, C.M.,Zhu, X.,Lerner, R.A.,Paulson, J.C.,Wilson, I.A.; A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site.; Nat Commun, 9:1264-1264, 2018; PubMed: 29593268; DOI: 10.1038/s41467-018-03663-5

Experimental method

X-RAY DIFFRACTION (2.2 Å)