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2QQB
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BU of 2qqb by Molmil
Crystal Structure of DtxR(M10A C102D) Complexed with Nickel(II)
Descriptor: Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION
Authors:D'Aquino, J.A, Lattimer, J.R, Denninger, A, D'Aquino, K.E, Ringe, D.
Deposit date:2007-07-26
Release date:2007-10-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR.
Biochemistry, 46, 2007
2QQA
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BU of 2qqa by Molmil
Crystal Structure of DtxR(E9A C102D) Complexed with Nickel(II)
Descriptor: Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION
Authors:D'Aquino, J.A, Lattimer, J.R, Denninger, A, D'Aquino, K.E, Ringe, D.
Deposit date:2007-07-26
Release date:2007-10-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR.
Biochemistry, 46, 2007
2P1Q
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BU of 2p1q by Molmil
Mechanism of Auxin Perception by the TIR1 ubiquitin ligase
Descriptor: 1H-INDOL-3-YLACETIC ACID, Auxin-responsive protein IAA7, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, N.
Deposit date:2007-03-06
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Mechanism of auxin perception by the TIR1 ubiquitin ligase.
Nature, 446, 2007
6UVU
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BU of 6uvu by Molmil
Crystal structure of the AntR antimony-specific transcriptional repressor
Descriptor: ArsR family transcriptional regulator
Authors:Thiruselvam, V, Banumathi, S, Palani, K, Manohar, R, Rosen, B.P.
Deposit date:2019-11-04
Release date:2020-11-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Functional and structural characterization of AntR, an Sb(III) responsive transcriptional repressor.
Mol.Microbiol., 116, 2021
6FAL
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BU of 6fal by Molmil
Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid as ligand
Descriptor: INDOLYLPROPIONIC ACID, Trp operon repressor
Authors:Stiel, A.C, Shanmugaratnam, S, Hocker, B.
Deposit date:2017-12-15
Release date:2019-01-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Tryptophan Repressor TrpR from E.coli: A ligand binding study
To Be Published
6F7F
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BU of 6f7f by Molmil
Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid
Descriptor: INDOLYLPROPIONIC ACID, Trp operon repressor
Authors:Stiel, A.C, Shanmugaratnam, S, Hocker, B.
Deposit date:2017-12-08
Release date:2019-03-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.128 Å)
Cite:Tryptophan Repressor TrpR: A study of ligand binding specificity
To Be Published
6F7G
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BU of 6f7g by Molmil
Tryptophan Repressor TrpR from E.coli with 5-Methyltryptamine
Descriptor: 2-(5-methyl-1~{H}-indol-3-yl)ethanamine, Trp operon repressor
Authors:Stiel, A.C, Shanmugaratnam, S, Hocker, B.
Deposit date:2017-12-08
Release date:2018-12-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.656 Å)
Cite:Tryptophan Repressor TrpR: A ligand specificity study
To Be Published
6F9K
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BU of 6f9k by Molmil
Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand
Descriptor: 5-methyl-L-tryptophan, SULFATE ION, Trp operon repressor
Authors:Stiel, A.C, Shanmugaratnam, S, Hocker, B.
Deposit date:2017-12-14
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:Tryptophan Repressor TrpR from E.coli: A ligand binding study
To Be Published
5JLU
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BU of 5jlu by Molmil
Crystal Structure of Adhesin competence repressor (AdcR) from Streptococcus pyogenes
Descriptor: Adhesin competence repressor, ZINC ION
Authors:Do, H, Kumaraswami, M.
Deposit date:2016-04-27
Release date:2017-05-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Adhesin competence repressor (AdcR) from Streptococcus pyogenes
To Be Published
6WMQ
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BU of 6wmq by Molmil
Crystal Structure of Human REV-ERBbeta Ligand Binding Domain Co-Bound to Heme and NCoR ID1 Peptide
Descriptor: Nuclear receptor Rev-ErbA beta variant 1, Nuclear receptor corepressor 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Mosure, S.A, Shang, J, Kojetin, D.J.
Deposit date:2020-04-21
Release date:2021-02-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERB beta.
Sci Adv, 7, 2021
3N00
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BU of 3n00 by Molmil
Crystal Structure of a deletion mutant of human Reverba ligand binding domain bound with an NCoR ID1 peptide determined to 2.60A
Descriptor: Nuclear receptor corepressor 1, Rev-erbA-alpha
Authors:Gampe, R, Nolte, R.
Deposit date:2010-05-13
Release date:2010-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Rev-erbalpha bound to N-CoR reveals a unique mechanism of nuclear receptor-co-repressor interaction.
Nat.Struct.Mol.Biol., 17, 2010
1UI5
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BU of 1ui5 by Molmil
Crystal structure of gamma-butyrolactone receptor (ArpA like protein)
Descriptor: A-factor receptor homolog
Authors:Natsume, R, Senda, T, Horinouchi, S.
Deposit date:2003-07-15
Release date:2004-07-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a gamma-butyrolactone autoregulator receptor protein in Streptomyces coelicolor A3(2)
J.Mol.Biol., 336, 2004
3MI7
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BU of 3mi7 by Molmil
An Enhanced Repressor of Human Papillomavirus E2 Protein
Descriptor: 1,2-ETHANEDIOL, Regulatory protein E2
Authors:Bohm, A, Baleja, J, Bose, K, Meinke, G.
Deposit date:2010-04-09
Release date:2011-04-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Design and characterization of an enhanced repressor of human papillomavirus E2 protein.
Faseb J., 25, 2011
6CBQ
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BU of 6cbq by Molmil
Crystal structure of QscR bound to agonist S3
Descriptor: (2S)-2-hexyl-N-[(3S)-2-oxooxolan-3-yl]decanamide, LuxR family transcriptional regulator
Authors:Churchill, M.E.A, Wysoczynski-Horita, C.L.
Deposit date:2018-02-05
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands.
Mol. Microbiol., 108, 2018
6RNX
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BU of 6rnx by Molmil
Crystal structure of the essential repressor DdrO from radiation-resistant Deinococcus bacteria (Deinococcus deserti)
Descriptor: CHLORIDE ION, HTH-type transcriptional regulator DdrOC
Authors:Arnoux, P, Siponen, M.I, Pignol, D, De Groot, A, Blanchard, L.
Deposit date:2019-05-09
Release date:2019-10-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Crystal structure of the transcriptional repressor DdrO: insight into the metalloprotease/repressor-controlled radiation response in Deinococcus.
Nucleic Acids Res., 47, 2019
6C9T
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BU of 6c9t by Molmil
Transcriptional repressor, CouR
Descriptor: CouR
Authors:Cogan, D.P, Nair, S.K.
Deposit date:2018-01-28
Release date:2018-05-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural basis of transcriptional regulation by CouR, a repressor of coumarate catabolism, inRhodopseudomonas palustris.
J. Biol. Chem., 293, 2018
6C28
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BU of 6c28 by Molmil
Transcriptional repressor, CouR, bound to p-coumaroyl-CoA
Descriptor: Transcriptional regulator, MarR family, p-coumaroyl-CoA
Authors:Cogan, D.P, Nair, S.K.
Deposit date:2018-01-07
Release date:2018-05-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural basis of transcriptional regulation by CouR, a repressor of coumarate catabolism, inRhodopseudomonas palustris.
J. Biol. Chem., 293, 2018
5CW8
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BU of 5cw8 by Molmil
Crystal structure of Mycobacterium tuberculosis KstR in complex with 3-oxo-4-cholesten-26-oyl-CoA
Descriptor: HTH-type transcriptional repressor KstR, S-{1-[5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,7-dihydroxy-6,6-dimethyl-3-oxido-8,12 -dioxo-2,4-dioxa-9,13-diaza-3lambda~5~-phosphapentadecan-15-yl} (2S,6R)-6-[(8S,9S,10R,13R,14S,17R)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta [a]phenanthren-17-yl]-2-methylheptanethioate (non-preferred name), TRIETHYLENE GLYCOL
Authors:Ho, N.A.T, Dawes, S, Kendall, S, Casabon, I, Crowe, A.M, Baker, E.N, Eltis, L.D, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-07-27
Release date:2016-02-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis.
J.Biol.Chem., 291, 2016
5CXG
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BU of 5cxg by Molmil
Crystal structure of Mycobacterium tuberculosis KstR in complex with PEG
Descriptor: DI(HYDROXYETHYL)ETHER, HTH-type transcriptional repressor KstR, TRIETHYLENE GLYCOL
Authors:Ho, N.A.T, Dawes, S, Kendall, S, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-07-28
Release date:2016-02-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1001 Å)
Cite:The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis.
J.Biol.Chem., 291, 2016
6RGX
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BU of 6rgx by Molmil
TETR(D) N82A MUTANT IN COMPLEX WITH DOXYCYCLINE AND MAGNESIUM
Descriptor: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
Deposit date:2019-04-17
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
1SAX
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BU of 1sax by Molmil
Three-dimensional structure of s.aureus methicillin-resistance regulating transcriptional repressor meci in complex with 25-bp ds-DNA
Descriptor: 5'-d(CAAAATTACAACTGTAATATCGGAG)-3', 5'-d(GCTCCGATATTACAGTTGTAATTTT)-3', Methicillin resistance regulatory protein mecI, ...
Authors:Garcia-Castellanos, R, Mallorqui-Fernandez, G, Marrero, A, Potempa, J, Coll, M, Gomis-Ruth, F.X.
Deposit date:2004-02-09
Release date:2004-04-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:On the transcriptional regulation of methicillin resistance: MecI repressor in complex with its operator
J.Biol.Chem., 279, 2004
5CXI
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BU of 5cxi by Molmil
Crystal structure of Mycobacterium tuberculosis KstR in complex with 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA (4-BNC-CoA)
Descriptor: 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA, HTH-type transcriptional repressor KstR
Authors:Ho, N.A.T, Dawes, S, Kendall, S, Casabon, I, Crowe, A.M, Baker, E.N, Eltis, L.D, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-07-29
Release date:2016-02-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis.
J.Biol.Chem., 291, 2016
5D4S
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BU of 5d4s by Molmil
Crystal Structure of AraR(DBD) in complex with operator ORX1
Descriptor: Arabinose metabolism transcriptional repressor, DNA (5'-D(*AP*AP*AP*TP*AP*CP*AP*TP*AP*CP*GP*TP*AP*CP*AP*AP*AP*TP*AP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*TP*AP*TP*TP*TP*GP*TP*AP*CP*GP*TP*AP*TP*GP*TP*AP*TP*T)-3')
Authors:Jain, D, Narayanan, N, Nair, D.T.
Deposit date:2015-08-08
Release date:2015-11-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.972 Å)
Cite:Plasticity in Repressor-DNA Interactions Neutralizes Loss of Symmetry in Bipartite Operators.
J.Biol.Chem., 291, 2016
5D4R
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BU of 5d4r by Molmil
Crystal Structure of AraR(DBD) in complex with operator ORE1
Descriptor: Arabinose metabolism transcriptional repressor, DNA (5'-D(*AP*TP*AP*TP*TP*TP*GP*TP*AP*CP*GP*TP*AP*CP*TP*AP*AP*TP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*TP*AP*GP*TP*AP*CP*GP*TP*AP*CP*AP*AP*AP*TP*A)-3')
Authors:Jain, D, Narayanan, N, Nair, D.T.
Deposit date:2015-08-08
Release date:2015-11-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Plasticity in Repressor-DNA Interactions Neutralizes Loss of Symmetry in Bipartite Operators.
J.Biol.Chem., 291, 2016
5E24
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BU of 5e24 by Molmil
Structure of the Su(H)-Hairless-DNA Repressor Complex
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), ...
Authors:Kovall, R.A, Yuan, Z.
Deposit date:2015-09-30
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structure and Function of the Su(H)-Hairless Repressor Complex, the Major Antagonist of Notch Signaling in Drosophila melanogaster.
Plos Biol., 14, 2016

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数据于2024-08-28公开中

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