8ZGT
 
 | | Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri state3 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Du, S, Deng, M.J, Xiao, J.Y. | | Deposit date: | 2024-05-09 | | Release date: | 2024-07-10 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (2.96 Å) | | Cite: | Structural insights into the high-affinity IgE receptor Fc epsilon RI complex.
Nature, 633, 2024
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9CEF
 | | Caulobacter crescentus FljN flagellar filament (symmetrized) | | Descriptor: | Flagellin FljN | | Authors: | Sanchez, J.C, Montemayor, E.J, Ploscariu, N.T, Parrell, D, Baumgardt, J.K, Yang, J.E, Sibert, B, Cai, K, Wright, E.R. | | Deposit date: | 2024-06-26 | | Release date: | 2024-08-28 | | Method: | ELECTRON MICROSCOPY (2.22 Å) | | Cite: | Direct evidence for multi-flagellin filament stabilization via atomic-level architecture of Caulobacter crescentus flagellar filaments
To Be Published
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9FCF
 | | Medicago truncatula 5'-ProFAR isomerase (HISN3) D57N mutant in complex with ProFAR | | Descriptor: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, chloroplastic, CHLORIDE ION, ... | | Authors: | Witek, W, Imiolczyk, B, Ruszkowski, M. | | Deposit date: | 2024-05-15 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Structural, kinetic, and evolutionary peculiarities of HISN3, a plant 5'-ProFAR isomerase.
Plant Physiol Biochem., 215, 2024
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9FOF
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8YS2
 | | Overall structure of Eastern Equine Encephalitis virus VLP in complex with the receptor VLDLR LA1-2 | | Descriptor: | CALCIUM ION, Capsid protein, Spike glycoprotein E1, ... | | Authors: | Cao, D, Ma, B, Cao, Z, Xu, X, Zhang, X, Xiang, Y. | | Deposit date: | 2024-03-22 | | Release date: | 2024-08-28 | | Method: | ELECTRON MICROSCOPY (5.2 Å) | | Cite: | The receptor VLDLR binds Eastern Equine Encephalitis virus through multiple distinct modes.
Nat Commun, 15, 2024
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9EOX
 | | SARS-CoV2 major protease in covalent complex with a soluble inhibitor. | | Descriptor: | 3C-like proteinase nsp5, POTASSIUM ION, Soluble inhibitor | | Authors: | Moche, M, Lennerstrand, J, Nyman, T, Strandback, E, Akaberi, D. | | Deposit date: | 2024-03-15 | | Release date: | 2024-09-04 | | Last modified: | 2024-09-11 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries.
Antimicrob.Agents Chemother., 2024
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8YS4
 | | Overall structure of Eastern Equine Encephalitis virus VLP in complex with the receptor VLDLR LA3-5 | | Descriptor: | CALCIUM ION, Capsid protein, Spike glycoprotein E1, ... | | Authors: | Cao, D, Ma, B, Cao, Z, Xu, X, Zhang, X, Xiang, Y. | | Deposit date: | 2024-03-22 | | Release date: | 2024-08-28 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | The receptor VLDLR binds Eastern Equine Encephalitis virus through multiple distinct modes.
Nat Commun, 15, 2024
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8Z4J
 | | Cryo-EM structure of CTR-bound type VII CRISPR-Cas complex at substrate-engaged state II | | Descriptor: | Protein structure, RNA (34-MER), RNA (38-MER), ... | | Authors: | Zhang, H, Deng, Z, Li, X. | | Deposit date: | 2024-04-17 | | Release date: | 2024-08-21 | | Last modified: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (2.97 Å) | | Cite: | Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 633, 2024
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9CBL
 | | Cryo-EM structure of epinephrine-bound alpha-2A-adrenergic receptor in complex with heterotrimeric Gi-protein | | Descriptor: | Endolysin,Alpha-2A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Lou, J.S, Su, M, Wang, J, Do, H.N, Miao, Y, Huang, X.Y. | | Deposit date: | 2024-06-19 | | Release date: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Distinct binding conformations of epinephrine with alpha- and beta-adrenergic receptors.
Exp.Mol.Med., 2024
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9FEE
 | | Cryo-EM structure of Trypanosoma cruzi glycosomal malate dehydrogenase | | Descriptor: | malate dehydrogenase | | Authors: | Lipinski, O, Sonani, R.R, Blat, A, Jemiola-Rzeminska, M, Patel, S.N, Sood, T, Dubin, G. | | Deposit date: | 2024-05-19 | | Release date: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | Cryo-EM structure of Trypanosoma cruzi glycosomal malate dehydrogenase
To Be Published
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9BQJ
 | | RO76 bound muOR-Gi1-scFv16 complex structure | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | Authors: | Wang, H, Majumdar, S, Kobilka, B.K. | | Deposit date: | 2024-05-10 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Signaling Modulation Mediated by Ligand Water Interactions with the Sodium Site at mu OR.
Acs Cent.Sci., 10, 2024
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9BP6
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9CET
 | | Guillardia theta Fanzor (GtFz) State 3 | | Descriptor: | DNA (28-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*TP*AP*AP*AP*GP*GP*CP*CP*CP*CP*GP*GP*G)-3'), Maltose/maltodextrin-binding periplasmic protein,Guillardia theta Fanzor1, ... | | Authors: | Xu, P, Saito, M, Zhang, F. | | Deposit date: | 2024-06-27 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 187, 2024
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9BHT
 | | Septin Hexameric Complex SEPT2/SEPT6/SEPT7 of Ciona intestinalis by Cryo-EM | | Descriptor: | CiSeptin-2, CiSeptin-6, CiSeptin-7, ... | | Authors: | Mendonca, D.C, Pereira, H.M, Garratt, R.C. | | Deposit date: | 2024-04-22 | | Release date: | 2024-07-10 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Structural Insights into Ciona intestinalis Septins: Complexes Suggest a Mechanism for Nucleotide-dependent Interfacial Cross-talk.
J.Mol.Biol., 436, 2024
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9B6I
 | | Cryo-EM structure of the avian great tit TRPM8 channel in complex with the antagonist TC-I 2014 | | Descriptor: | 3-{7-(trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-benzimidazol-2-yl}-1-oxa-2-azaspiro[4.5]dec-2-ene, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Yin, Y, Park, C.-G, Zhang, F, Fedor, J, Feng, S, Suo, Y, Im, W, Lee, S.-Y. | | Deposit date: | 2024-03-25 | | Release date: | 2024-08-21 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Mechanisms of sensory adaptation and inhibition of the cold and menthol receptor TRPM8.
Sci Adv, 10, 2024
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9F33
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8YUT
 | | Cryo-EM structure of the amthamine-bound H2R-Gs complex | | Descriptor: | 5-(2-azanylethyl)-4-methyl-1,3-thiazol-2-amine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y. | | Deposit date: | 2024-03-27 | | Release date: | 2024-06-05 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
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9AXE
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9F34
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9GD1
 | | Structure of Chd1 bound to a hexasome-nucleosome complex with a dyad-to-dyad distance of 103 bp. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... | | Authors: | Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L. | | Deposit date: | 2024-08-04 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.
Mol.Cell, 84, 2024
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9J2N
 | | Cryo-EM structure of the human glucose transporter, GLUT7 in outward-facing open conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 2, facilitated glucose transporter member 7 | | Authors: | Lee, S.S, Kim, S, Jin, M.S. | | Deposit date: | 2024-08-07 | | Release date: | 2024-09-25 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structure of the human glucose transporter GLUT7.
Biochem.Biophys.Res.Commun., 738, 2024
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8YZ5
 | | SARS-CoV-2 Delta Spike in complex with Fab of JE-5C | | Descriptor: | Fab heavy chain of JE-5C, Fab light chain of JE-5C, Spike glycoprotein | | Authors: | Chen, X, Wu, Y.-M. | | Deposit date: | 2024-04-06 | | Release date: | 2024-06-05 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.93 Å) | | Cite: | The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine.
Plos Pathog., 20, 2024
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9GD2
 | | Structure of Chd1 bound to a dinucleosome with a dyad-to-dyad distance of 103 bp. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... | | Authors: | Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L. | | Deposit date: | 2024-08-04 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.
Mol.Cell, 84, 2024
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9ETU
 | | Archaellum filament from the Halobacterium salinarum deltaAgl27 strain | | Descriptor: | 3-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-beta-D-glucopyranuronic acid-(1-4)-beta-D-glucopyranose, Archaellin | | Authors: | Grossman-Haham, I, Shahar, A. | | Deposit date: | 2024-03-27 | | Release date: | 2024-07-17 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Perturbed N-glycosylation of Halobacterium salinarum archaellum filaments leads to filament bundling and compromised cell motility.
Nat Commun, 15, 2024
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8YZ6
 | | SARS-CoV-2 Spike (BA.1) in complex with Fab of JH-8B | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain of JH-8B, ... | | Authors: | Chen, X, Wu, Y.-M. | | Deposit date: | 2024-04-06 | | Release date: | 2024-06-05 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (4.55 Å) | | Cite: | The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine.
Plos Pathog., 20, 2024
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