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2QOG
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Crotoxin B, the basic PLA2 from Crotalus durissus terrificus.
Descriptor: CALCIUM ION, Phospholipase A2 CB1, Phospholipase A2 CB2
Authors:Marchi-Salvador, D.P, Correa, L.C, Fontes, M.R.M.
Deposit date:2007-07-20
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Insights into the role of oligomeric state on the biological activities of crotoxin: crystal structure of a tetrameric phospholipase A2 formed by two isoforms of crotoxin B from Crotalus durissus terrificus venom.
Proteins, 72, 2008
3U8B
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BU of 3u8b by Molmil
Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
Descriptor: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
Authors:Lee, L.K, Bryant, K.J, Bouveret, R, Lei, P.-W, Duff, A.P, Harrop, S.J, Huang, E.P, Harvey, R.P, Gelb, M.H, Gray, P.P, Curmi, P.M, Cunningham, A.M, Church, W.B, Scott, K.F.
Deposit date:2011-10-16
Release date:2012-10-17
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
5WZS
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BU of 5wzs by Molmil
Crystal structure of human secreted phospholipase A2 group IIE with Compound 8
Descriptor: 2-[2-methyl-1-(naphthalen-1-ylmethyl)-3-oxamoyl-indol-4-yl]oxyethanoic acid, CALCIUM ION, CHLORIDE ION, ...
Authors:Hou, S, Xu, J, Xu, T, Liu, J.
Deposit date:2017-01-18
Release date:2018-01-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE
Sci Rep, 7, 2017
3U8H
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BU of 3u8h by Molmil
Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
Descriptor: (S)-5-(4-BENZYLOXY-PHENYL)-4-(7-PHENYL-HEPTANOYLAMINO)-PENTANOIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Lee, L.K, Bryant, K.J, Bouveret, R, Lei, P.-W, Duff, A.P, Harrop, S.J, Huang, E.P, Harvey, R.P, Gelb, M.H, Gray, P.P, Curmi, P.M, Cunningham, A.M, Church, W.B, Scott, K.F.
Deposit date:2011-10-17
Release date:2012-10-17
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
3Q4Y
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Crystal structure of group I phospholipase A2 at 2.3 A resolution in 40% ethanol revealed the critical elements of hydrophobicity of the substrate-binding site
Descriptor: CALCIUM ION, ETHANOL, Phospholipase A2 isoform 3
Authors:Shukla, P.K, Kaushik, S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2010-12-26
Release date:2011-01-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of group I phospholipase A2 at 2.3 A resolution in 40% ethanol revealed the critical elements of hydrophobicity of the substrate-binding site
To be Published
1OWS
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BU of 1ows by Molmil
Crystal structure of a C49 Phospholipase A2 from Indian cobra reveals carbohydrate binding in the hydrophobic channel
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Phospholipase A2, ZINC ION
Authors:Jabeen, T, Jasti, J, Singh, N, Singh, R.K, Sharma, S, Kaur, P, Singh, T.P.
Deposit date:2003-03-30
Release date:2003-05-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a C49 Phospholipase A2 from Indian cobra reveals carbohydrate binding in the hydrophobic channel
To be Published
1PSH
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BU of 1psh by Molmil
CRYSTAL STRUCTURE OF PHOSPHOLIPASE A2 FROM INDIAN COBRA REVEALS A TRIMERIC ASSOCIATION
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Fremont, D, Xuong, N.-H, Wilson, I.
Deposit date:1992-07-28
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of phospholipase A2 from Indian cobra reveals a trimeric association.
Proc.Natl.Acad.Sci.USA, 90, 1993
1S8G
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BU of 1s8g by Molmil
Crystal structure of Lys49-Phospholipase A2 from Agkistrodon contortrix laticinctus, fatty acid bound form
Descriptor: GLYCEROL, LAURIC ACID, Phospholipase A2 homolog, ...
Authors:Ambrosio, A.L.B, de Souza, D.H.F, Nonato, M.C, Selistre de Araujo, H.S, Ownby, C.L, Garratt, R.C.
Deposit date:2004-02-02
Release date:2004-02-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Molecular Mechanism for Lys49-Phospholipase A2 Activity Based on Ligand-induced Conformational Change.
J.Biol.Chem., 280, 2005
4DBK
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BU of 4dbk by Molmil
Crystal structure of porcine pancreatic phospholipase A2 complexed with berberine
Descriptor: BERBERINE, CALCIUM ION, Phospholipase A2, ...
Authors:Naveen, C.D, Abhilash, J, Prasanth, G.K, Sadasivan, C, Haridas, M.
Deposit date:2012-01-16
Release date:2012-01-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of porcine pancreatic phospholipase A2 complexed with berberine
To be Published
1P7O
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BU of 1p7o by Molmil
Crystal structure of phospholipase A2 (MIPLA4) from Micropechis ikaheka
Descriptor: PHOSPHOLIPASE A2
Authors:Lok, S.M, Swaminathan, K.
Deposit date:2003-05-05
Release date:2004-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and function comparison of Micropechis ikaheka snake venom phospholipase A2 isoenzymes
FEBS J., 272, 2005
2B03
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Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Taurochenodeoxycholate
Descriptor: CALCIUM ION, Phospholipase A2, major isoenzyme, ...
Authors:Pan, Y.H, Bahnson, B.J, Jain, M.K.
Deposit date:2005-09-12
Release date:2006-11-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for bile salt inhibition of pancreatic phospholipase A2.
J.Mol.Biol., 369, 2007
2GNS
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BU of 2gns by Molmil
Design of specific peptide inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II phospholipase A2 and a designed pentapeptide Ala- Leu- Val- Tyr- Lys at 2.3 A resolution
Descriptor: ALVYK, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
Authors:Singh, N, Sharma, S, Somvanshi, R.K, Dey, S, Singh, T.P.
Deposit date:2006-04-11
Release date:2006-04-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design of specific peptide inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II phospholipase A2 and a designed pentapeptide Ala - Leu - Val - Tyr - Lys at 2.3 A resolution
To be Published
4FGA
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BU of 4fga by Molmil
Design of peptide inhibitors of group II phospholipase A2: Crystal structure of the complex of phospholipsae A2 with a designed tripeptide, Ala- Tyr- Lys at 2.3 A resolution
Descriptor: AYK, Phospholipase A2 VRV-PL-VIIIa
Authors:Shukla, P.K, Sinha, M, Dey, S, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2012-06-04
Release date:2012-06-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design of peptide inhibitors of group II phospholipase A2: Crystal structure of the complex of phospholipsae A2 with a designed tripeptide, Ala- Tyr- Lys at 2.3 A resolution
To be Published
3FVJ
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Crystal structure of phospholipase A2 1B crystallized in the presence of octyl sulfate
Descriptor: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
Authors:Pan, Y.H.
Deposit date:2009-01-15
Release date:2010-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a premicellar complex of alkyl sulfates with the interfacial binding surfaces of four subunits of phospholipase A2.
Biochim.Biophys.Acta, 1804, 2010
1Y75
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A new form of catalytically inactive phospholipase A2 with an unusual disulphide bridge Cys 32- Cys 49 reveals recognition for N-acetylglucosmine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, phospholipase A2 isoform 5, ...
Authors:Jabeen, T, Singh, N, Jasti, J, Singh, R.K, Sharma, S, Perbandt, M, Betzel, C, Kaur, P, Srinivasan, A, Singh, T.P.
Deposit date:2004-12-08
Release date:2005-05-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a heterodimer of phospholipase A2 from Naja naja sagittifera at 2.3 A resolution reveals the presence of a new PLA2-like protein with a novel cys 32-Cys 49 disulphide bridge with a bound sugar at the substrate-binding site
Proteins, 62, 2006
3BJW
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Crystal Structure of ecarpholin S complexed with suramin
Descriptor: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Phospholipase A2
Authors:Zhou, X, Sivaraman, J.
Deposit date:2007-12-04
Release date:2007-12-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Characterization of Myotoxic Ecarpholin S from Echis carinatus Venom
Biophys.J., 95, 2008
2OK9
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BU of 2ok9 by Molmil
PrTX-I-BPB
Descriptor: ISOPROPYL ALCOHOL, Phospholipase A2 homolog 1, p-Bromophenacyl bromide
Authors:Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R.
Deposit date:2007-01-16
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of a phospholipase A(2) homolog complexed with p-bromophenacyl bromide reveals important structural changes associated with the inhibition of myotoxic activity.
Biochim.Biophys.Acta, 1794, 2009
5VFN
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BU of 5vfn by Molmil
Crystal structure of BnSP-7 from Bothrops pauloensis complexed with cinnamic acid
Descriptor: 1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE, Basic phospholipase A2 homolog BnSP-7, HYDROCINNAMIC ACID, ...
Authors:De Lima, L.F.G, Fontes, M.R.M.
Deposit date:2017-04-08
Release date:2017-12-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.389 Å)
Cite:Structural studies with BnSP-7 reveal an atypical oligomeric conformation compared to phospholipases A2-like toxins.
Biochimie, 142, 2017
1TP2
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BU of 1tp2 by Molmil
Crystal structure of the complex of group II phospholipaseA2 dimer with a fatty acid tridecanoic acid at 2.4 A resolution
Descriptor: ACETIC ACID, N-TRIDECANOIC ACID, Phospholipase A2 VRV-PL-VIIIa, ...
Authors:Singh, N, Jabeen, T, Sharma, S, Singh, T.P.
Deposit date:2004-06-15
Release date:2004-06-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the complex of group II phospholipaseA2 dimer with a fatty acid tridecanoic acid at 2.4 A resolution
To be Published
4G5I
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BU of 4g5i by Molmil
Crystal Structure of Porcine pancreatic PlA2 in complex with DBP
Descriptor: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
Authors:Prasanth, G.K, Naveen, C.D, Mandal, P.K, Karthe, P, Haridas, M, Sadasivan, C.
Deposit date:2012-07-18
Release date:2012-11-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Porcine pancreatic PlA2 in complex with DBP
TO BE PUBLISHED
3L30
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Crystal structure of porcine pancreatic phospholipase A2 complexed with dihydroxyberberine
Descriptor: 4,14-dihydro-8H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline-9,10-diol, CALCIUM ION, CHLORIDE ION, ...
Authors:Naveen, C, Prasanth, G.K, Abhilash, J, Pradeep, M, Ponnuraj, K, Sadasivan, C, Haridas, M.
Deposit date:2009-12-16
Release date:2010-01-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of porcine pancreatic phospholipase A2 complexed with dihydroxyberberine
To be Published
5P2P
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X-RAY STRUCTURE OF PHOSPHOLIPASE A2 COMPLEXED WITH A SUBSTRATE-DERIVED INHIBITOR
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2, PHOSPHONIC ACID 2-DODECANOYLAMINO-HEXYL ESTER PROPYL ESTER
Authors:Dijkstra, B.W, Thunnissen, M.M.G.M, Kalk, K.H, Drenth, J.
Deposit date:1990-09-01
Release date:1991-10-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray structure of phospholipase A2 complexed with a substrate-derived inhibitor.
Nature, 347, 1990
1GMZ
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BU of 1gmz by Molmil
Crystal structure of the D49 phospholipase A2 piratoxin III from Bothrops pirajai.
Descriptor: ISOPROPYL ALCOHOL, PHOSPHOLIPASE A2
Authors:Rigden, D.J, Lee, W.H, Polikarpov, I.
Deposit date:2001-09-27
Release date:2001-11-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of the D49 Phospholipase A2 Piratoxin III from Bothrops Pirajai Reveals Unprecedented Structural Displacement of the Calcium-Binding Loop: Possible Relationship to Cooperative Substrate Binding
Acta Crystallogr.,Sect.D, 59, 2003
4P2P
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BU of 4p2p by Molmil
AN INDEPENDENT CRYSTALLOGRAPHIC REFINEMENT OF PORCINE PHOSPHOLIPASE A2 AT 2.4 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Finzel, B.C, Ohlendorf, D.H, Weber, P.C, Salemme, F.R.
Deposit date:1991-10-22
Release date:1992-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:An independent crystallographic refinement of porcine phospholipase A2 at 2.4 A resolution
Acta Crystallogr.,Sect.B, 47, 1991
5WZT
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BU of 5wzt by Molmil
Crystal structure of human secreted phospholipase A2 group IIE with Compound 14
Descriptor: 2-[1-[(3-bromophenyl)methyl]-2-methyl-3-oxamoyl-indol-4-yl]oxyethanoic acid, CALCIUM ION, DIMETHYL SULFOXIDE, ...
Authors:Hou, S, Xu, J, Xu, T, Liu, J.
Deposit date:2017-01-18
Release date:2018-01-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE
Sci Rep, 7, 2017

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