6ESG
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![BU of 6esg by Molmil](/molmil-images/mine/6esg) | Nucleosome breathing : Class 2 | Descriptor: | DNA (141-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Bilokapic, S, Halic, M. | Deposit date: | 2017-10-20 | Release date: | 2017-12-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (5.4 Å) | Cite: | Histone octamer rearranges to adapt to DNA unwrapping. Nat. Struct. Mol. Biol., 25, 2018
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5NL0
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![BU of 5nl0 by Molmil](/molmil-images/mine/5nl0) | Crystal structure of a 197-bp palindromic 601L nucleosome in complex with linker histone H1 | Descriptor: | DNA (197-MER), Histone H1.0-B, Histone H2A type 1, ... | Authors: | Garcia-Saez, I, Petosa, C, Dimitrov, S. | Deposit date: | 2017-04-03 | Release date: | 2017-05-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (5.4 Å) | Cite: | Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1. Mol. Cell, 66, 2017
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7X3T
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![BU of 7x3t by Molmil](/molmil-images/mine/7x3t) | Cryo-EM structure of ISW1a-dinucleosome | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (343-MER), ... | Authors: | Lifei, L, Kangjing, C, Chen, Z. | Deposit date: | 2022-03-01 | Release date: | 2023-09-20 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (5.4 Å) | Cite: | Structure of the ISW1a complex bound to the dinucleosome. Nat.Struct.Mol.Biol., 31, 2024
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5OY7
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![BU of 5oy7 by Molmil](/molmil-images/mine/5oy7) | Structure of the 4_601_157 tetranucleosome (P1 form) | Descriptor: | CHLORIDE ION, DNA (619-MER), Histone H2A, ... | Authors: | Ekundayo, B, Richmond, T.J, Schalch, T. | Deposit date: | 2017-09-07 | Release date: | 2017-09-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (5.774 Å) | Cite: | Capturing Structural Heterogeneity in Chromatin Fibers. J. Mol. Biol., 429, 2017
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6W5N
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![BU of 6w5n by Molmil](/molmil-images/mine/6w5n) | Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class05) | Descriptor: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. | Deposit date: | 2020-03-13 | Release date: | 2021-03-31 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
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6PWV
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![BU of 6pwv by Molmil](/molmil-images/mine/6pwv) | Cryo-EM structure of MLL1 core complex bound to the nucleosome | Descriptor: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | Deposit date: | 2019-07-23 | Release date: | 2019-12-18 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
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6ESI
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![BU of 6esi by Molmil](/molmil-images/mine/6esi) | Nucleosome breathing : Class 4 | Descriptor: | DNA (133-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Bilokapic, S, Halic, M. | Deposit date: | 2017-10-20 | Release date: | 2017-12-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Histone octamer rearranges to adapt to DNA unwrapping. Nat. Struct. Mol. Biol., 25, 2018
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7ZSB
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![BU of 7zsb by Molmil](/molmil-images/mine/7zsb) | |
8ETT
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![BU of 8ett by Molmil](/molmil-images/mine/8ett) | Class1 of the INO80-Hexasome complex | Descriptor: | DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. | Deposit date: | 2022-10-17 | Release date: | 2023-07-12 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (6.68 Å) | Cite: | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
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5OXV
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![BU of 5oxv by Molmil](/molmil-images/mine/5oxv) | Structure of the 4_601_157 tetranucleosome (C2 form) | Descriptor: | DNA STRAND 1 (601-based sequence model), DNA STRAND 2 (601-based sequence model), Histone H2A, ... | Authors: | Ekundayo, B, Schalch, T. | Deposit date: | 2017-09-07 | Release date: | 2017-10-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (6.721 Å) | Cite: | Capturing Structural Heterogeneity in Chromatin Fibers. J. Mol. Biol., 429, 2017
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6JMA
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![BU of 6jma by Molmil](/molmil-images/mine/6jma) | cryo-EM structure of DOT1L bound to H2B ubiquitinated nucleosome | Descriptor: | DNA I&J, Histone H2A, Histone H2B 1.1, ... | Authors: | Jang, S, Song, J.J. | Deposit date: | 2019-03-07 | Release date: | 2019-05-15 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase. Genes Dev., 33, 2019
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6W5I
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![BU of 6w5i by Molmil](/molmil-images/mine/6w5i) | Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class01) | Descriptor: | DNA (147-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. | Deposit date: | 2020-03-13 | Release date: | 2021-03-31 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
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7EGP
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![BU of 7egp by Molmil](/molmil-images/mine/7egp) | The structure of SWI/SNF-nucleosome complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP9, Actin-related protein 7, ... | Authors: | Chen, Z.C, Chen, K.J, He, Z.Y, Ye, Y.P. | Deposit date: | 2021-03-24 | Release date: | 2022-01-12 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Structure of the SWI/SNF complex bound to the nucleosome and insights into the functional modularity. Cell Discov, 7, 2021
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6KW3
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![BU of 6kw3 by Molmil](/molmil-images/mine/6kw3) | The ClassA RSC-Nucleosome Complex | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... | Authors: | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | Deposit date: | 2019-09-05 | Release date: | 2019-11-13 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (7.13 Å) | Cite: | Structure of the RSC complex bound to the nucleosome. Science, 366, 2019
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6JM9
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![BU of 6jm9 by Molmil](/molmil-images/mine/6jm9) | cryo-EM structure of DOT1L bound to unmodified nucleosome | Descriptor: | DNA strand I, DNA strand J, Histone H2A, ... | Authors: | Jang, S, Song, J.J. | Deposit date: | 2019-03-07 | Release date: | 2019-05-15 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (7.3 Å) | Cite: | Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase. Genes Dev., 33, 2019
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6KW4
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![BU of 6kw4 by Molmil](/molmil-images/mine/6kw4) | The ClassB RSC-Nucleosome Complex | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... | Authors: | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | Deposit date: | 2019-09-06 | Release date: | 2019-11-13 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (7.55 Å) | Cite: | Structure of the RSC complex bound to the nucleosome. Science, 366, 2019
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8JHO
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![BU of 8jho by Molmil](/molmil-images/mine/8jho) | |
7VVZ
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![BU of 7vvz by Molmil](/molmil-images/mine/7vvz) | NuA4 bound to the nucleosome | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... | Authors: | Qu, K, Chen, Z. | Deposit date: | 2021-11-09 | Release date: | 2022-08-10 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (8.8 Å) | Cite: | Structure of the NuA4 acetyltransferase complex bound to the nucleosome. Nature, 610, 2022
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6UXW
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![BU of 6uxw by Molmil](/molmil-images/mine/6uxw) | SWI/SNF nucleosome complex with ADP-BeFx | Descriptor: | 601 sequence bottom strand, 601 sequence top strand, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | He, Y, Han, Y. | Deposit date: | 2019-11-08 | Release date: | 2020-03-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (8.96 Å) | Cite: | Cryo-EM structure of SWI/SNF complex bound to a nucleosome. Nature, 579, 2020
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1ZBB
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![BU of 1zbb by Molmil](/molmil-images/mine/1zbb) | Structure of the 4_601_167 Tetranucleosome | Descriptor: | DNA STRAND 1 (ARBITRARY MODEL SEQUENCE), DNA STRAND 2 (ARBITRARY MODEL SEQUENCE), HISTONE H3, ... | Authors: | Schalch, T, Duda, S, Sargent, D.F, Richmond, T.J. | Deposit date: | 2005-04-08 | Release date: | 2005-07-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (9 Å) | Cite: | X-ray structure of a tetranucleosome and its implications for the chromatin fibre. Nature, 436, 2005
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6X0N
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![BU of 6x0n by Molmil](/molmil-images/mine/6x0n) | |
6KW5
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![BU of 6kw5 by Molmil](/molmil-images/mine/6kw5) | The ClassC RSC-Nucleosome Complex | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... | Authors: | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | Deposit date: | 2019-09-06 | Release date: | 2020-09-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (10.13 Å) | Cite: | Structure of the RSC complex bound to the nucleosome To Be Published
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6TDA
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![BU of 6tda by Molmil](/molmil-images/mine/6tda) | Structure of SWI/SNF chromatin remodeler RSC bound to a nucleosome | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC58, ... | Authors: | Wagner, F.R, Dienemann, C, Wang, H, Stuetzer, A, Tegunov, D, Urlaub, H, Cramer, P. | Deposit date: | 2019-11-08 | Release date: | 2020-03-18 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (15 Å) | Cite: | Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome. Nature, 579, 2020
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6O22
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![BU of 6o22 by Molmil](/molmil-images/mine/6o22) | Structure of Asf1-H3:H4-Rtt109-Vps75 histone chaperone-lysine acetyltransferase complex with the histone substrate. | Descriptor: | Histone H3.2, Histone H4, Histone acetyltransferase RTT109, ... | Authors: | Danilenko, N, Carlomagno, T, Kirkpatrick, J.P. | Deposit date: | 2019-02-22 | Release date: | 2019-07-31 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR, SOLUTION SCATTERING | Cite: | Histone chaperone exploits intrinsic disorder to switch acetylation specificity. Nat Commun, 10, 2019
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7MBN
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![BU of 7mbn by Molmil](/molmil-images/mine/7mbn) | Cryo-EM structure of MLL1-NCP (H3K4M) complex, mode02 | Descriptor: | DNA (146-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Park, S.H, Ayoub, A, Lee, Y.T, Dou, Y, Cho, U. | Deposit date: | 2021-04-01 | Release date: | 2021-12-29 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY | Cite: | Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes. Biochemistry, 61, 2022
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