2JA6
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![BU of 2ja6 by Molmil](/molmil-images/mine/2ja6) | CPD lesion containing RNA Polymerase II elongation complex B | Descriptor: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TP*TTP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', ... | Authors: | Brueckner, F, Hennecke, U, Carell, T, Cramer, P. | Deposit date: | 2006-11-23 | Release date: | 2007-02-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | CPD damage recognition by transcribing RNA polymerase II. Science, 315, 2007
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7ML1
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![BU of 7ml1 by Molmil](/molmil-images/mine/7ml1) | RNA polymerase II pre-initiation complex (PIC2) | Descriptor: | BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K. | Deposit date: | 2021-04-27 | Release date: | 2022-02-02 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Mol.Cell, 82, 2022
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7ZSA
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![BU of 7zsa by Molmil](/molmil-images/mine/7zsa) | |
3GTO
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![BU of 3gto by Molmil](/molmil-images/mine/3gto) | Backtracked RNA polymerase II complex with 15mer RNA | Descriptor: | DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D. | Deposit date: | 2009-03-27 | Release date: | 2009-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution. Science, 324, 2009
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2R93
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![BU of 2r93 by Molmil](/molmil-images/mine/2r93) | Elongation complex of RNA polymerase II with a hepatitis delta virus-derived RNA stem loop | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Lehmann, E, Brueckner, F, Cramer, P. | Deposit date: | 2007-09-12 | Release date: | 2007-11-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Molecular basis of RNA-dependent RNA polymerase II activity. Nature, 450, 2007
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5C4X
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![BU of 5c4x by Molmil](/molmil-images/mine/5c4x) | Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G. | Deposit date: | 2015-06-18 | Release date: | 2015-08-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble. Mol.Cell, 59, 2015
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1Y1Y
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![BU of 1y1y by Molmil](/molmil-images/mine/1y1y) | RNA Polymerase II-TFIIS-DNA/RNA complex | Descriptor: | 5'-D(P*TP*AP*CP*GP*CP*CP*T)-3', 5'-R(P*AP*GP*GP*C)-3', DNA-directed RNA polymerase II 13.6 kDa polypeptide, ... | Authors: | Cramer, P, Kettenberger, H, Armache, K.-J. | Deposit date: | 2004-11-19 | Release date: | 2004-12-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS. Mol.Cell, 16, 2004
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4X67
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![BU of 4x67 by Molmil](/molmil-images/mine/4x67) | Crystal structure of elongating yeast RNA polymerase II stalled at oxidative Cyclopurine DNA lesions. | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Wang, L, Chong, J, Wang, D. | Deposit date: | 2014-12-07 | Release date: | 2015-02-04 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions. Proc.Natl.Acad.Sci.USA, 112, 2015
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1NIK
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![BU of 1nik by Molmil](/molmil-images/mine/1nik) | Wild Type RNA Polymerase II | Descriptor: | DNA-directed RNA polymerase I, II and III 23 kDa polypeptide, DNA-directed RNA polymerase II, ... | Authors: | Bushnell, D.A, Kornberg, R.D. | Deposit date: | 2002-12-24 | Release date: | 2003-04-29 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Complete, 12-subunit RNA Polymerase II at 4.1-A resolution: implications for the initiation of transcription. Proc.Natl.Acad.Sci.USA, 100, 2003
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2B8K
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![BU of 2b8k by Molmil](/molmil-images/mine/2b8k) | 12-subunit RNA Polymerase II | Descriptor: | DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ... | Authors: | Meyer, P.A, Ye, P, Zhang, M, Suh, M.H, Fu, J. | Deposit date: | 2005-10-07 | Release date: | 2006-06-20 | Last modified: | 2012-06-13 | Method: | X-RAY DIFFRACTION (4.15 Å) | Cite: | Phasing RNA Polymerase II Using Intrinsically Bound Zn Atoms: An Updated Structural Model. Structure, 14, 2006
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1NT9
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![BU of 1nt9 by Molmil](/molmil-images/mine/1nt9) | Complete 12-subunit RNA polymerase II | Descriptor: | DNA-DIRECTED RNA POLYMERASE II 13.6 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 19 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT, ... | Authors: | Armache, K.-J, Kettenberger, H, Cramer, P. | Deposit date: | 2003-01-29 | Release date: | 2003-04-22 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Architecture of initiation-competent 12-subunit RNA polymerase II Proc.Natl.Acad.Sci.USA, 100, 2003
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5C4A
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![BU of 5c4a by Molmil](/molmil-images/mine/5c4a) | Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Barnes, C.O, Calero, M, Malik, I, Saphr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G. | Deposit date: | 2015-06-17 | Release date: | 2015-08-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble. Mol.Cell, 59, 2015
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1R9S
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![BU of 1r9s by Molmil](/molmil-images/mine/1r9s) | RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MATCHED NUCLEOTIDE | Descriptor: | DNA strand, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ... | Authors: | Westover, K.D, Bushnell, D.A, Kornberg, R.D. | Deposit date: | 2003-10-30 | Release date: | 2004-11-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (4.25 Å) | Cite: | Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center. Cell(Cambridge,Mass.), 119, 2004
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3K1F
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![BU of 3k1f by Molmil](/molmil-images/mine/3k1f) | Crystal structure of RNA Polymerase II in complex with TFIIB | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Kostrewa, D, Zeller, M.E, Armache, K.-J, Seizl, M, Leike, K, Thomm, M, Cramer, P. | Deposit date: | 2009-09-27 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | RNA polymerase II-TFIIB structure and mechanism of transcription initiation. Nature, 462, 2009
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3QT1
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![BU of 3qt1 by Molmil](/molmil-images/mine/3qt1) | RNA polymerase II variant containing A Chimeric RPB9-C11 subunit | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Ruan, W, Lehmann, E, Thomm, M, Kostrewa, D, Cramer, P. | Deposit date: | 2011-02-22 | Release date: | 2011-03-23 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | Evolution of two modes of intrinsic RNA polymerase transcript cleavage. J.Biol.Chem., 286, 2011
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2NVZ
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![BU of 2nvz by Molmil](/molmil-images/mine/2nvz) | RNA Polymerase II elongation complex with UTP, updated 11/2006 | Descriptor: | 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... | Authors: | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | Deposit date: | 2006-11-14 | Release date: | 2006-12-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis Cell(Cambridge,Mass.), 127, 2006
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5FYW
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![BU of 5fyw by Molmil](/molmil-images/mine/5fyw) | Transcription initiation complex structures elucidate DNA opening (OC) | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | Authors: | Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P. | Deposit date: | 2016-03-10 | Release date: | 2016-05-18 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.35 Å) | Cite: | Transcription Initiation Complex Structures Elucidate DNA Opening Nature, 533, 2016
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6I84
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![BU of 6i84 by Molmil](/molmil-images/mine/6i84) | Structure of transcribing RNA polymerase II-nucleosome complex | Descriptor: | DNA (158-MER), DNA (170-MER), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Farnung, L, Vos, S.M, Cramer, P. | Deposit date: | 2018-11-19 | Release date: | 2019-01-02 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structure of transcribing RNA polymerase II-nucleosome complex. Nat Commun, 9, 2018
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8TVS
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![BU of 8tvs by Molmil](/molmil-images/mine/8tvs) | Cryo-EM structure of backtracked Pol II in complex with Rad26 | Descriptor: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | Deposit date: | 2023-08-18 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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1R5U
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![BU of 1r5u by Molmil](/molmil-images/mine/1r5u) | RNA POLYMERASE II TFIIB COMPLEX | Descriptor: | DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ... | Authors: | Bushnell, D.A, Westover, K.D, Davis, R, Kornberg, R.D. | Deposit date: | 2003-10-13 | Release date: | 2004-02-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms. Science, 303, 2004
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1Y77
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![BU of 1y77 by Molmil](/molmil-images/mine/1y77) | Complete RNA Polymerase II elongation complex with substrate analogue GMPCPP | Descriptor: | 5'-D(*AP*AP*GP*TP*AP*CP*T)-3', 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*T*CP*GP*CP*CP*TP*GP*GP*TP*CP*TP*G)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ... | Authors: | Kettenberger, H, Armache, K.-J, Cramer, P. | Deposit date: | 2004-12-08 | Release date: | 2005-01-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS Mol.Cell, 16, 2004
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7UIF
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![BU of 7uif by Molmil](/molmil-images/mine/7uif) | Mediator-PIC Early (Core B) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | Deposit date: | 2022-03-29 | Release date: | 2023-02-15 | Last modified: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
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8TVQ
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![BU of 8tvq by Molmil](/molmil-images/mine/8tvq) | Cryo-EM structure of CPD stalled 10-subunit Pol II in complex with Rad26 | Descriptor: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | Deposit date: | 2023-08-18 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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5OQJ
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![BU of 5oqj by Molmil](/molmil-images/mine/5oqj) | STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH | Descriptor: | DNA repair helicase RAD25, DNA repair helicase RAD3, DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Schilbach, S, Hantsche, M, Tegunov, D, Dienemann, C, Wigge, C, Henning, U, Cramer, P. | Deposit date: | 2017-08-11 | Release date: | 2018-04-25 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature, 551, 2017
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6GYL
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![BU of 6gyl by Molmil](/molmil-images/mine/6gyl) | Structure of a yeast closed complex with distorted DNA (core CCdist) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | Deposit date: | 2018-06-30 | Release date: | 2018-12-05 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
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