8TVQ

Cryo-EM structure of CPD stalled 10-subunit Pol II in complex with Rad26

Summary for 8TVQ

Entry DOI	10.2210/pdb8tvq/pdb
EMDB information	41648
Descriptor	DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases II subunit RPABC4, DNA repair and recombination protein RAD26, ... (16 entities in total)
Functional Keywords	rna polymerase ii, rad26, cpd lesion, transcription-coupled dna repair, transcription, transcription-dna-rna complex, transcription/dna/rna
Biological source	Saccharomyces cerevisiae More
Total number of polymer chains	14
Total formula weight	539160.54
Authors	Sarsam, R.D.,Lahiri, I.,Leschziner, A.E. (deposition date: 2023-08-18, release date: 2024-01-24)
Primary citation	Sarsam, R.D.,Xu, J.,Lahiri, I.,Gong, W.,Li, Q.,Oh, J.,Zhou, Z.,Hou, P.,Chong, J.,Hao, N.,Li, S.,Wang, D.,Leschziner, A.E. Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121:e2314245121-e2314245121, 2024 Cited by PubMed: 38194460 DOI: 10.1073/pnas.2314245121 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.6 Å)

Structure validation