8SEL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sel by Molmil](/molmil-images/mine/8sel) | |
8OWK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8owk by Molmil](/molmil-images/mine/8owk) | Lipidic amyloid-beta(1-40) fibril - polymorph L3-L3 | Descriptor: | Amyloid-beta A4 protein | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | Deposit date: | 2023-04-28 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
|
|
8OLQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8olq by Molmil](/molmil-images/mine/8olq) | DI3 Abeta fibril from tg-SwDI mouse | Descriptor: | Amyloid-beta protein 42 | Authors: | Zielinski, M, Peralta Reyes, F.S, Gremer, L, Schemmert, S, Frieg, B, Willuweit, A, Donner, L, Elvers, M, Nilsson, L.N.G, Syvanen, S, Sehlin, D, Ingelsson, M, Willbold, D, Schroeder, G.F. | Deposit date: | 2023-03-30 | Release date: | 2023-11-29 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease. Nat.Neurosci., 26, 2023
|
|
5OQV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5oqv by Molmil](/molmil-images/mine/5oqv) | Near-atomic resolution fibril structure of complete amyloid-beta(1-42) by cryo-EM | Descriptor: | Amyloid beta A4 protein | Authors: | Gremer, L, Schoelzel, D, Schenk, C, Reinartz, E, Labahn, J, Ravelli, R, Tusche, M, Lopez-Iglesias, C, Hoyer, W, Heise, H, Willbold, D, Schroeder, G.F. | Deposit date: | 2017-08-14 | Release date: | 2017-09-13 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Fibril structure of amyloid-beta (1-42) by cryo-electron microscopy. Science, 358, 2017
|
|
8OLG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8olg by Molmil](/molmil-images/mine/8olg) | DI2 Abeta fibril from tg-SwDI mouse | Descriptor: | Amyloid-beta protein 42 | Authors: | Zielinski, M, Peralta Reyes, F.S, Gremer, L, Schemmert, S, Frieg, B, Willuweit, A, Donner, L, Elvers, M, Nilsson, L.N.G, Syvanen, S, Sehlin, D, Ingelsson, M, Willbold, D, Schroeder, G.F. | Deposit date: | 2023-03-30 | Release date: | 2023-11-29 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease. Nat.Neurosci., 26, 2023
|
|
6SHS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6shs by Molmil](/molmil-images/mine/6shs) | Abeta fibril (Morphology I) | Descriptor: | Amyloid-beta precursor protein | Authors: | Kollmer, M, Fandrich, M. | Deposit date: | 2019-08-08 | Release date: | 2019-11-06 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Cryo-EM structure and polymorphism of A beta amyloid fibrils purified from Alzheimer's brain tissue. Nat Commun, 10, 2019
|
|
5AEF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5aef by Molmil](/molmil-images/mine/5aef) | Electron cryo-microscopy of an Abeta(1-42)amyloid fibril | Descriptor: | AMYLOID BETA A4 PROTEIN | Authors: | Schmidt, M, Rohou, A, Lasker, K, Yadav, J.K, Schiene-Fischer, C, Fandrich, M, Grigorieff, N. | Deposit date: | 2015-08-29 | Release date: | 2015-10-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | Peptide Dimer Structure in an Abeta(1-42) Fibril Visualized with Cryo-Em Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
2OTK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2otk by Molmil](/molmil-images/mine/2otk) | |
6TI7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ti7 by Molmil](/molmil-images/mine/6ti7) | Mixing Abeta(1-40) and Abeta(1-42) peptides generates unique amyloid fibrils | Descriptor: | Amyloid-beta precursor protein | Authors: | Cerofolini, L, Ravera, E, Bologna, S, Wiglenda, T, Boddrich, A, Purfurst, B, Benilova, A, Korsak, M, Gallo, G, Rizzo, D, Gonnelli, L, Fragai, M, De Strooper, B, Wanker, E.E, Luchinat, C. | Deposit date: | 2019-11-21 | Release date: | 2020-07-22 | Last modified: | 2024-06-19 | Method: | SOLID-STATE NMR | Cite: | Mixing A beta (1-40) and A beta (1-42) peptides generates unique amyloid fibrils. Chem.Commun.(Camb.), 56, 2020
|
|
1QXC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qxc by Molmil](/molmil-images/mine/1qxc) | NMR structure of the fragment 25-35 of beta amyloid peptide in 20/80 v:v hexafluoroisopropanol/water mixture | Descriptor: | 11-mer peptide from Amyloid beta A4 protein | Authors: | D'Ursi, A.M, Armenante, M.R, Guerrini, R, Salvadori, S, Sorrentino, G, Picone, D. | Deposit date: | 2003-09-05 | Release date: | 2004-09-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of amyloid beta-peptide (25-35) in different media J.Med.Chem., 47, 2004
|
|
1QWP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qwp by Molmil](/molmil-images/mine/1qwp) | NMR analysis of 25-35 fragment of beta amyloid peptide | Descriptor: | 11-mer peptide from Amyloid beta A4 protein | Authors: | D'Ursi, A.M, Armenante, M.R, Guerrini, R, Salvadori, S, Sorrentino, G, Picone, D. | Deposit date: | 2003-09-03 | Release date: | 2004-09-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of amyloid beta-peptide (25-35) in different media J.Med.Chem., 47, 2004
|
|
1QYT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qyt by Molmil](/molmil-images/mine/1qyt) | Solution structure of fragment (25-35) of beta amyloid peptide in SDS micellar solution | Descriptor: | 11-mer peptide from Amyloid beta A4 protein | Authors: | D'Ursi, A.M, Armenante, M.R, Guerrini, R, Salvadori, S, Sorrentino, G, Picone, D. | Deposit date: | 2003-09-12 | Release date: | 2004-12-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of amyloid beta-peptide (25-35) in different media J.Med.Chem., 47, 2004
|
|
1QCM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qcm by Molmil](/molmil-images/mine/1qcm) | AMYLOID BETA PEPTIDE (25-35), NMR, 20 STRUCTURES | Descriptor: | AMYLOID BETA PEPTIDE | Authors: | Kohno, T, Kobayashi, K, Maeda, T, Sato, K, Takashima, A. | Deposit date: | 1996-07-19 | Release date: | 1997-07-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Three-dimensional structures of the amyloid beta peptide (25-35) in membrane-mimicking environment. Biochemistry, 35, 1996
|
|
6SZF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6szf by Molmil](/molmil-images/mine/6szf) | Solution structure of the amyloid beta-peptide (1-42) | Descriptor: | Amyloid-beta precursor protein | Authors: | Grimaldi, M, Santoro, A, Stillitano, I, Buonocore, M, D'Ursi, A.M. | Deposit date: | 2019-10-02 | Release date: | 2020-10-14 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Exploring the Early Stages of the Amyloid A beta (1-42) Peptide Aggregation Process: An NMR Study. Pharmaceuticals, 14, 2021
|
|
8B9R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8b9r by Molmil](/molmil-images/mine/8b9r) | Molecular structure of Cu(II)-bound amyloid-beta monomer implicated in inhibition of peptide self-assembly in Alzheimer's disease | Descriptor: | Amyloid-beta A4 protein, COPPER (II) ION | Authors: | Abelein, A, Ciofi-Baffoni, S, Morman, C, Kumar, R, Giachetti, A, Piccioli, M, Biverstal, H. | Deposit date: | 2022-10-06 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Molecular Structure of Cu(II)-Bound Amyloid-beta Monomer Implicated in Inhibition of Peptide Self-Assembly in Alzheimer's Disease. Jacs Au, 2, 2022
|
|
1AMC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1amc by Molmil](/molmil-images/mine/1amc) | |
6TI5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ti5 by Molmil](/molmil-images/mine/6ti5) | A New Structural Model of Abeta(1-40) Fibrils | Descriptor: | Amyloid-beta precursor protein | Authors: | Bertini, I, Gonnelli, L, Luchinat, C, Mao, J, Nesi, A. | Deposit date: | 2019-11-21 | Release date: | 2020-07-22 | Last modified: | 2024-06-19 | Method: | SOLID-STATE NMR | Cite: | Mixing A beta (1-40) and A beta (1-42) peptides generates unique amyloid fibrils. Chem.Commun.(Camb.), 56, 2020
|
|
6TI6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ti6 by Molmil](/molmil-images/mine/6ti6) | Mixing Abeta(1-40) and Abeta(1-42) peptides generates unique amyloid fibrils | Descriptor: | Amyloid-beta precursor protein | Authors: | Cerofolini, L, Ravera, E, Bologna, S, Wiglenda, T, Boddrich, A, Purfurst, B, Benilova, A, Korsak, M, Gallo, G, Rizzo, D, Gonnelli, L, Fragai, M, De Strooper, B, Wanker, E.E, Luchinat, C. | Deposit date: | 2019-11-21 | Release date: | 2020-07-22 | Last modified: | 2024-06-19 | Method: | SOLID-STATE NMR | Cite: | Mixing A beta (1-40) and A beta (1-42) peptides generates unique amyloid fibrils. Chem.Commun.(Camb.), 56, 2020
|
|
2LMO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lmo by Molmil](/molmil-images/mine/2lmo) | |
1HZ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hz3 by Molmil](/molmil-images/mine/1hz3) | ALZHEIMER'S DISEASE AMYLOID-BETA PEPTIDE (RESIDUES 10-35) | Descriptor: | A-BETA AMYLOID | Authors: | Zhang, S, Iwata, K, Lachenmann, M.J, Peng, J.W, Li, S, Stimson, E.R, Lu, Y, Felix, A.M, Maggio, J.E, Lee, J.P. | Deposit date: | 2001-01-23 | Release date: | 2001-01-31 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The Alzheimer's peptide a beta adopts a collapsed coil structure in water. J.Struct.Biol., 130, 2000
|
|
2LNQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lnq by Molmil](/molmil-images/mine/2lnq) | 40-residue D23N beta amyloid fibril | Descriptor: | P3(40) | Authors: | Qiang, W, Yau, W, Luo, Y, Mattson, M.P, Tycko, R. | Deposit date: | 2012-01-03 | Release date: | 2012-02-08 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Antiparallel beta-sheet architecture in Iowa-mutant beta-amyloid fibrils. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
2LOH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2loh by Molmil](/molmil-images/mine/2loh) | |
2LFM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lfm by Molmil](/molmil-images/mine/2lfm) | |
7Y8Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y8q by Molmil](/molmil-images/mine/7y8q) | Amyloid-beta assemblage on GM1-containing membranes | Descriptor: | Amyloid-beta protein 40 | Authors: | Yagi-Utsumi, M, Itoh, S.G, Okumura, H, Yanagisawa, K, Kato, K, Nishimura, K. | Deposit date: | 2022-06-24 | Release date: | 2023-07-05 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | The Double-Layered Structure of Amyloid-beta Assemblage on GM1-Containing Membranes Catalytically Promotes Fibrillization. Acs Chem Neurosci, 14, 2023
|
|
2LMQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lmq by Molmil](/molmil-images/mine/2lmq) | |