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4ZNX
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BU of 4znx by Molmil
Crystal structure of the Fyn-SH3 domain in complex with the high affinity peptide APP12
Descriptor: APP12, Tyrosine-protein kinase Fyn
Authors:Camara-Artigas, A.
Deposit date:2015-05-05
Release date:2016-06-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase.
Acta Crystallogr.,Sect.F, 72, 2016
7Y4N
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BU of 7y4n by Molmil
Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos
Descriptor: Growth factor receptor-bound protein 2
Authors:Pooppadi, M.S, Ikeya, T, Sugasawa, H, Watanabe, R, Mishima, M, Inomata, K, Ito, Y.
Deposit date:2022-06-15
Release date:2022-08-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos.
Biochem.Biophys.Res.Commun., 625, 2022
8KDX
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BU of 8kdx by Molmil
Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current
Descriptor: Microtubule-associated protein tau, Tyrosine-protein kinase Fyn
Authors:Padavattan, S, Jos, S.
Deposit date:2023-08-10
Release date:2024-02-28
Method:X-RAY DIFFRACTION (1.01 Å)
Cite:Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current.
J.Mol.Biol., 436, 2024
7JT9
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BU of 7jt9 by Molmil
Fgr SH3 domain crystal structure
Descriptor: Tyrosine-protein kinase Fgr
Authors:Perez, I, Berndt, S, Gurevich, V.V, Iverson, T.M.
Deposit date:2020-08-17
Release date:2022-01-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A Model for the Signal Initiation Complex Between Arrestin-3 and the Src Family Kinase Fgr.
J.Mol.Biol., 434, 2022
6NMW
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BU of 6nmw by Molmil
Crystal structure of the human Lyn SH3 domain
Descriptor: Tyrosine-protein kinase Lyn
Authors:Berndt, S, Gurevich, V.V, Iverson, T.M.
Deposit date:2019-01-12
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.199 Å)
Cite:Crystal structure of the SH3 domain of human Lyn non-receptor tyrosine kinase.
PLoS ONE, 14, 2019
1M3A
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BU of 1m3a by Molmil
Solution structure of a circular form of the truncated N-terminal SH3 domain from oncogene protein c-Crk.
Descriptor: Proto-oncogene C-crk
Authors:Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D.
Deposit date:2002-06-27
Release date:2003-08-05
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain
To be Published
1M8M
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BU of 1m8m by Molmil
SOLID-STATE MAS NMR STRUCTURE OF THE A-SPECTRIN SH3 DOMAIN
Descriptor: SPECTRIN ALPHA CHAIN, BRAIN
Authors:Castellani, F, Van Rossum, B, Diehl, A, Schubert, M, Rehbein, K, Oschkinat, H.
Deposit date:2002-07-25
Release date:2002-11-20
Last modified:2024-05-22
Method:SOLID-STATE NMR
Cite:Structure of a protein determined by solid-state magic-angle-spinning NMR spectroscopy
Nature, 420, 2002
1W1F
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BU of 1w1f by Molmil
SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE
Descriptor: TYROSINE-PROTEIN KINASE LYN
Authors:Bauer, F, Schweimer, K, Hoffmann, S, Roesch, P, Sticht, H.
Deposit date:2004-06-17
Release date:2005-07-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Characterization of Lyn-SH3 Domain in Complex with a Herpesviral Protein Reveals an Extended Recognition Motif that Enhances Binding Affinity.
Protein Sci., 14, 2005
1WA7
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BU of 1wa7 by Molmil
SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE IN COMPLEX WITH A HERPESVIRAL LIGAND
Descriptor: HYPOTHETICAL 28.7 KDA PROTEIN IN DHFR 3'REGION (ORF1), TYROSINE-PROTEIN KINASE LYN
Authors:Bauer, F, Schweimer, K, Hoffmann, S, Roesch, P, Sticht, H.
Deposit date:2004-10-25
Release date:2005-07-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck.
Biochemistry, 41, 2002
6IPY
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BU of 6ipy by Molmil
His-tagged Fyn SH3 domain R96I mutant
Descriptor: Tyrosine-protein kinase Fyn
Authors:Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.343 Å)
Cite:Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
2YUP
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BU of 2yup by Molmil
Solution structure of the second SH3 domain of human Vinexin
Descriptor: Vinexin
Authors:Abe, H, Tochio, N, Miyamoto, K, Saito, K, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-06
Release date:2007-10-09
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the second SH3 domain of human Vinexin
To be Published
2YT6
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BU of 2yt6 by Molmil
Solution structure of the SH3_1 domain of Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
Descriptor: Adult male urinary bladder cDNA, RIKEN full-length enriched library, clone:9530076O17 product:Yamaguchi sarcoma viral (v-yes) oncogene homolog
Authors:Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-05
Release date:2008-04-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the SH3_1 domain of Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
To be Published
6IPZ
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BU of 6ipz by Molmil
Fyn SH3 domain R96W mutant, crystallized with 18-crown-6
Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Tyrosine-protein kinase Fyn
Authors:Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.576 Å)
Cite:Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
4Y92
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BU of 4y92 by Molmil
Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain E97T-Q128R mutant
Descriptor: GLYCEROL, Protein-tyrosine kinase, SULFATE ION, ...
Authors:Camara-Artigas, A, Bacarizo, J.
Deposit date:2015-02-16
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain E97T-Q128R mutant
to be published
5UL6
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BU of 5ul6 by Molmil
The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions
Descriptor: Adapter molecule crk, Proline-rich motif of nonstructural protein 1 of influenza a virus
Authors:Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H.
Deposit date:2017-01-24
Release date:2017-08-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Molecular Mechanisms Underlying the Hijack of Host Proteins by the 1918 Spanish Influenza Virus.
ACS Chem. Biol., 12, 2017
5VEI
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BU of 5vei by Molmil
Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
Descriptor: Sorbin and SH3 domain-containing protein 2, UNKNOWN ATOM OR ION
Authors:Liu, Y, Tempel, W, Huang, H, Gu, J, Liu, K, Sidhu, S.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2017-04-04
Release date:2017-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
To be Published
7YXW
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BU of 7yxw by Molmil
Structure of the p22phox A200G mutant in complex with p47phox peptide
Descriptor: Cytochrome b-245 light chain, Neutrophil cytosol factor 1
Authors:Cukier, C.D, Vuillard, L.M, Komjati, B, Szlavik, Z.
Deposit date:2022-02-16
Release date:2022-03-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics
Acs Med.Chem.Lett., 13, 2022
5XGG
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BU of 5xgg by Molmil
Crystal Structure C-terminal SH3 domain of Myosin IB from Entamoeba histolytica
Descriptor: SULFATE ION, Unconventional myosin IB
Authors:Gautam, G, Gourinath, S.
Deposit date:2017-04-13
Release date:2017-08-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structure of the PEG-bound SH3 domain of myosin IB from Entamoeba histolytica reveals its mode of ligand recognition
Acta Crystallogr D Struct Biol, 73, 2017
6RO9
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BU of 6ro9 by Molmil
Human spectrin SH3 domain D48G, E7V, K60V
Descriptor: Spectrin alpha, non-erythrocytic 1
Authors:Reverter, D, Navarro, S, Ventura, S.
Deposit date:2019-05-10
Release date:2020-06-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.814 Å)
Cite:Human spectrin SH3 domain D48G, E7V, K60V
To Be Published
6EDF
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BU of 6edf by Molmil
Fragment of a tyrosine-protein kinase
Descriptor: FYN, GLYCEROL, UNKNOWN ATOM OR ION
Authors:Tempel, W, Huang, H, Sochirca, I, Liu, K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Sidhu, S.S, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-08-09
Release date:2018-08-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Fragment of a tyrosine-protein kinase
To be Published
6SCW
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BU of 6scw by Molmil
SH3-subunit of chicken alpha spectrin solved by NMR
Descriptor: Spectrin alpha chain, non-erythrocytic 1 isoform X11
Authors:Grohe, K, Hebrank, C, Linser, R.
Deposit date:2019-07-25
Release date:2020-08-12
Last modified:2024-01-31
Method:SOLUTION NMR
Cite:Protein Motional Details Revealed by Complementary Structural Biology Techniques.
Structure, 28, 2020
3IQL
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BU of 3iql by Molmil
Crystal structure of the rat endophilin-A1 SH3 domain
Descriptor: CHLORIDE ION, Endophilin-A1
Authors:Trempe, J.F, Kozlov, G, Camacho, E.M, Gehring, K.
Deposit date:2009-08-20
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination.
Mol.Cell, 36, 2009
6SDF
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BU of 6sdf by Molmil
N-terminal SH3 domain of Grb2 protein
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Growth factor receptor-bound protein 2
Authors:Bolgov, A.A, Korban, S.A, Luzik, D.A, Rogacheva, O.N, Zhemkov, V.A, Kim, M, Skrynnikov, N.R, Bezprozvanny, I.B.
Deposit date:2019-07-26
Release date:2020-01-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the SH3 domain of growth factor receptor-bound protein 2.
Acta Crystallogr.,Sect.F, 76, 2020
3I9Q
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BU of 3i9q by Molmil
Crystal Structure of the triple mutant S19G-P20D-R21S of alpha spectrin SH3 domain
Descriptor: SULFATE ION, Spectrin alpha chain
Authors:Camara-Artigas, A, Gavira, J.A.
Deposit date:2009-07-12
Release date:2009-12-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The effect of a proline residue on the rate of growth and the space group of alpha-spectrin SH3-domain crystals.
Acta Crystallogr.,Sect.D, 65, 2009
5XG9
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BU of 5xg9 by Molmil
Crystal Structure of PEG-bound SH3 domain of Myosin IB from Entamoeba histolytica
Descriptor: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, PENTAETHYLENE GLYCOL, ...
Authors:Gautam, G, Gourinath, S.
Deposit date:2017-04-13
Release date:2017-08-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of the PEG-bound SH3 domain of myosin IB from Entamoeba histolytica reveals its mode of ligand recognition
Acta Crystallogr D Struct Biol, 73, 2017

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