8KDX

Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current

Summary for 8KDX

• Entry DOI: 10.2210/pdb8kdx/pdb
• Descriptor: Tyrosine-protein kinase Fyn, Microtubule-associated protein tau (3 entities in total)
• Functional Keywords: alzheimer's disease, fyn kinase, sh3 domain, tau protein and pxxp motif., peptide binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 8497.20

Authors

Padavattan, S.,Jos, S. (deposition date: 2023-08-10, release date: 2024-02-28)

• Primary citation: Jos, S.,Poulose, R.,Kambaru, A.,Gogoi, H.,Dalavaikodihalli Nanjaiah, N.,Padmanabhan, B.,Mehta, B.,Padavattan, S.; Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current.; J.Mol.Biol., 436:168445-168445, 2024; PubMed: 38218365; DOI: 10.1016/j.jmb.2024.168445

Experimental method

X-RAY DIFFRACTION (1.01 Å)