7TVK
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6UIH
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6NRX
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![BU of 6nrx by Molmil](/molmil-images/mine/6nrx) | Crystal structure of DIP-eta IG1 homodimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dpr-interacting protein eta, isoform B, ... | Authors: | Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. | Deposit date: | 2019-01-24 | Release date: | 2019-02-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. Elife, 8, 2019
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6NRW
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![BU of 6nrw by Molmil](/molmil-images/mine/6nrw) | Crystal structure of Dpr1 IG1 bound to DIP-eta IG1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. | Deposit date: | 2019-01-24 | Release date: | 2019-02-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. Elife, 8, 2019
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6NRQ
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![BU of 6nrq by Molmil](/molmil-images/mine/6nrq) | Crystal structure of Dpr10 IG1 bound to DIP-alpha IG1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Defective proboscis extension response 10, isoform A, ... | Authors: | Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. | Deposit date: | 2019-01-24 | Release date: | 2019-02-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. Elife, 8, 2019
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6NS1
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![BU of 6ns1 by Molmil](/molmil-images/mine/6ns1) | Crystal structure of DIP-gamma IG1+IG2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Dpr-interacting protein gamma | Authors: | Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. | Deposit date: | 2019-01-24 | Release date: | 2019-02-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. Elife, 8, 2019
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6SNQ
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![BU of 6snq by Molmil](/molmil-images/mine/6snq) | Crystal structures of human PGM1 isoform 2 | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, Phosphoglucomutase-1, ZINC ION | Authors: | Backe, P.H, Laerdahl, J.K, Kittelsen, L.S, Dalhus, B, Morkrid, L, Bjoras, M. | Deposit date: | 2019-08-27 | Release date: | 2020-04-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the alpha-D-phosphohexomutase superfamily. Sci Rep, 10, 2020
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1JPM
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![BU of 1jpm by Molmil](/molmil-images/mine/1jpm) | L-Ala-D/L-Glu Epimerase | Descriptor: | GLYCEROL, L-Ala-D/L-Glu Epimerase, MAGNESIUM ION | Authors: | Gulick, A.M, Schmidt, D.M.Z, Gerlt, J.A, Rayment, I. | Deposit date: | 2001-08-02 | Release date: | 2001-12-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Evolution of enzymatic activities in the enolase superfamily: crystal structures of the L-Ala-D/L-Glu epimerases from Escherichia coli and Bacillus subtilis. Biochemistry, 40, 2001
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6SNO
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![BU of 6sno by Molmil](/molmil-images/mine/6sno) | Crystal structures of human PGM1 isoform 2 | Descriptor: | 1-O-phosphono-alpha-D-glucopyranose, Phosphoglucomutase-1, ZINC ION | Authors: | Backe, P.H, Laerdahl, J.K, Kittelsen, L.S, Dalhus, B, Morkrid, L, Bjoras, M. | Deposit date: | 2019-08-27 | Release date: | 2020-04-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the alpha-D-phosphohexomutase superfamily. Sci Rep, 10, 2020
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2ODA
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![BU of 2oda by Molmil](/molmil-images/mine/2oda) | Crystal Structure of PSPTO_2114 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hypothetical protein PSPTO_2114, MAGNESIUM ION | Authors: | Peisach, E, Allen, K.N, Dunaway-Mariano, D, Wang, L, Burroughs, A.M, Aravind, L. | Deposit date: | 2006-12-22 | Release date: | 2007-09-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The X-ray crystallographic structure and activity analysis of a Pseudomonas-specific subfamily of the HAD enzyme superfamily evidences a novel biochemical function. Proteins, 70, 2007
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1JPD
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![BU of 1jpd by Molmil](/molmil-images/mine/1jpd) | L-Ala-D/L-Glu Epimerase | Descriptor: | L-Ala-D/L-Glu Epimerase | Authors: | Gulick, A.M, Schmidt, D.M.Z, Gerlt, J.A, Rayment, I. | Deposit date: | 2001-08-01 | Release date: | 2001-12-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Evolution of enzymatic activities in the enolase superfamily: crystal structures of the L-Ala-D/L-Glu epimerases from Escherichia coli and Bacillus subtilis. Biochemistry, 40, 2001
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8BN8
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![BU of 8bn8 by Molmil](/molmil-images/mine/8bn8) | METTL3-METTL14 heterodimer bound to the SAM competitive small molecule inhibitor STM3006 | Descriptor: | 2-[[4-(6-bromanyl-2~{H}-indazol-4-yl)-1,2,3-triazol-1-yl]methyl]-6-[(4,4-dimethylpiperidin-1-yl)methyl]imidazo[1,2-a]pyridine, N6-adenosine-methyltransferase catalytic subunit, N6-adenosine-methyltransferase non-catalytic subunit | Authors: | Pilka, E.S, Thomas, B, Blackaby, W, Hardick, D, Feeney, K, Ridgill, M, Rotty, B, Rausch, O. | Deposit date: | 2022-11-13 | Release date: | 2023-09-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.213 Å) | Cite: | Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity. Cancer Discov, 13, 2023
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5XD8
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![BU of 5xd8 by Molmil](/molmil-images/mine/5xd8) | Crystal structure analysis of 3,6-anhydro-L-galactonate cycloisomerase | Descriptor: | 3,6-anhydro-alpha-L-galactonate cycloisomerase, MAGNESIUM ION | Authors: | Lee, S, Choi, I.-G, Kim, H.-Y. | Deposit date: | 2017-03-27 | Release date: | 2017-09-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.505 Å) | Cite: | Crystal structure analysis of 3,6-anhydro-l-galactonate cycloisomerase suggests emergence of novel substrate specificity in the enolase superfamily Biochem. Biophys. Res. Commun., 491, 2017
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2VU5
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![BU of 2vu5 by Molmil](/molmil-images/mine/2vu5) | Crystal structure of Pndk from Bacillus anthracis | Descriptor: | NUCLEOSIDE DIPHOSPHATE KINASE | Authors: | Misra, G, Aggarwal, A, Dube, D, Zaman, M.S, Singh, Y, Ramachandran, R. | Deposit date: | 2008-05-21 | Release date: | 2009-03-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the Bacillus Anthracis Nucleoside Diphosphate Kinase and its Characterization Reveals an Enzyme Adapted to Perform Under Stress Conditions. Proteins, 76, 2009
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4R90
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![BU of 4r90 by Molmil](/molmil-images/mine/4r90) | Anti CD70 Llama glama Fab 27B3 | Descriptor: | Anti CD70 Llama glama Fab 27B3 Heavy chain, Anti CD70 Llama glama Fab 27B3 Light chain, CALCIUM ION, ... | Authors: | Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I. | Deposit date: | 2014-09-03 | Release date: | 2015-06-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.746 Å) | Cite: | Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform. MAbs, 7, 2015
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4R96
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![BU of 4r96 by Molmil](/molmil-images/mine/4r96) | Structure of a Llama Glama Fab 48A2 against human cMet | Descriptor: | Llama glama Fab 48A2 against human cMet H chain, Llama glama Fab 48A2 against human cMet L chain | Authors: | Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I. | Deposit date: | 2014-09-03 | Release date: | 2015-06-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform. MAbs, 7, 2015
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8TBF
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![BU of 8tbf by Molmil](/molmil-images/mine/8tbf) | Tricomplex of RMC-7977, KRAS WT, and CypA | Descriptor: | (1R,5S,6r)-N-[(1P,7S,9S,13S,20M)-20-{5-(4-cyclopropylpiperazin-1-yl)-2-[(1S)-1-methoxyethyl]pyridin-3-yl}-21-ethyl-17,17-dimethyl-8,14-dioxo-15-oxa-4-thia-9,21,27,28-tetraazapentacyclo[17.5.2.1~2,5~.1~9,13~.0~22,26~]octacosa-1(24),2,5(28),19,22,25-hexaen-7-yl]-3-oxabicyclo[3.1.0]hexane-6-carboxamide, 1,2-ETHANEDIOL, GTPase KRas, ... | Authors: | Tomlinson, A.C.A, Chen, A, Knox, J.E, Yano, J.K. | Deposit date: | 2023-06-28 | Release date: | 2024-02-07 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature, 629, 2024
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6PPC
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![BU of 6ppc by Molmil](/molmil-images/mine/6ppc) | Solution structure of conotoxin MiXXVIIA | Descriptor: | Conopeptide phi-MiXXVIIA | Authors: | Daly, N.L, Dekan, Z, Jin, A.H, Alewood, P.F. | Deposit date: | 2019-07-06 | Release date: | 2019-08-14 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Conotoxin phi-MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti-Apoptotic Activity. Angew. Chem. Int. Ed. Engl., 56, 2017
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8TZZ
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![BU of 8tzz by Molmil](/molmil-images/mine/8tzz) | SpG Cas9 with NGC PAM DNA target | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*CP*GP*TP*TP*TP*GP*TP*AP*CP*TP*GP*CP*AP*GP*CP*G)-3'), DNA (5'-D(P*TP*CP*TP*CP*AP*TP*CP*TP*TP*TP*AP*TP*GP*CP*GP*TP*C)-3'), ... | Authors: | Bravo, J.P.K, Hibshman, G.N, Taylor, D.W. | Deposit date: | 2023-08-28 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T7S
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![BU of 8t7s by Molmil](/molmil-images/mine/8t7s) | SpRYmer bound to NAC PAM DNA | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-06-21 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8U3Y
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![BU of 8u3y by Molmil](/molmil-images/mine/8u3y) | SpG Cas9 with NGG PAM DNA target | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*CP*GP*TP*TP*TP*GP*TP*AP*CP*TP*CP*CP*AP*GP*CP*G)-3'), DNA (5'-D(P*TP*CP*TP*CP*AP*TP*CP*TP*TP*TP*AP*TP*GP*CP*GP*TP*C)-3'), ... | Authors: | Bravo, J.P.K, Hibshman, G.N, Taylor, D.W. | Deposit date: | 2023-09-08 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T78
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![BU of 8t78 by Molmil](/molmil-images/mine/8t78) | SpRY-Cas9:gRNA complex bound to non-target DNA with 8 bp R-loop | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-06-19 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T79
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![BU of 8t79 by Molmil](/molmil-images/mine/8t79) | SpRY-Cas9:gRNA complex bound to non-target DNA with 10 bp R-loop | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-06-20 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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1A7C
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![BU of 1a7c by Molmil](/molmil-images/mine/1a7c) | HUMAN PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 IN COMPLEX WITH A PENTAPEPTIDE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-ribopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PENTAPEPTIDE, ... | Authors: | Xue, Y, Inghardt, T, Sjolin, L, Deinum, J. | Deposit date: | 1998-03-12 | Release date: | 1999-03-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide Structure, 6, 1998
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6QAJ
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![BU of 6qaj by Molmil](/molmil-images/mine/6qaj) | Structure of the tripartite motif of KAP1/TRIM28 | Descriptor: | Endolysin,Transcription intermediary factor 1-beta, ZINC ION | Authors: | Stoll, G.A, Oda, S, Yu, M, Modis, Y. | Deposit date: | 2018-12-19 | Release date: | 2019-07-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.901 Å) | Cite: | Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing. Proc.Natl.Acad.Sci.USA, 116, 2019
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