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2YD3
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BU of 2yd3 by Molmil
Crystal structure of the N-terminal Ig1-2 module of Human Receptor Protein Tyrosine Phosphatase Sigma
Descriptor: CHLORIDE ION, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE S, SODIUM ION
Authors:Coles, C.H, Shen, Y, Tenney, A.P, Siebold, C, Sutton, G.C, Lu, W, Gallagher, J.T, Jones, E.Y, Flanagan, J.G, Aricescu, A.R.
Deposit date:2011-03-17
Release date:2011-04-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Proteoglycan-Specific Molecular Switch for Rptp Sigma Clustering and Neuronal Extension.
Science, 332, 2011
2YD2
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BU of 2yd2 by Molmil
Crystal structure of the N-terminal Ig1-2 module of Human Receptor Protein Tyrosine Phosphatase Sigma
Descriptor: CHLORIDE ION, IODIDE ION, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE S
Authors:Coles, C.H, Shen, Y, Tenney, A.P, Siebold, C, Sutton, G.C, Lu, W, Gallagher, J.T, Jones, E.Y, Flanagan, J.G, Aricescu, A.R.
Deposit date:2011-03-17
Release date:2011-04-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.552 Å)
Cite:Proteoglycan-Specific Molecular Switch for Rptp Sigma Clustering and Neuronal Extension.
Science, 332, 2011
2V5M
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BU of 2v5m by Molmil
Structural basis for Dscam isoform specificity
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DSCAM, GLYCEROL
Authors:Meijers, R, Puettmann-Holgado, R, Skiniotis, G, Liu, J.-H, Walz, T, Schmucker, D, Wang, J.-H.
Deposit date:2007-07-06
Release date:2007-09-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Basis of Dscam Isoform Specificity
Nature, 449, 2007
2V5S
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BU of 2v5s by Molmil
Structural basis for Dscam isoform specificity
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DSCAM
Authors:Meijers, R, Puettmann-Holgado, R, Skiniotis, G, Liu, J.-H, Walz, T, Schmucker, D, Wang, J.-H.
Deposit date:2007-07-09
Release date:2007-09-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Dscam Isoform Specificity
Nature, 449, 2007
2V9Q
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BU of 2v9q by Molmil
First and second Ig domains from human Robo1
Descriptor: MERCURY (II) ION, ROUNDABOUT HOMOLOG 1
Authors:Morlot, C, Cusack, S, McCarthy, A.A.
Deposit date:2007-08-25
Release date:2007-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V5R
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BU of 2v5r by Molmil
Structural basis for Dscam isoform specificity
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DSCAM, GLYCEROL
Authors:Meijers, R, Puettmann-Holgado, R, Skiniotis, G, Liu, J.-H, Walz, T, Schmucker, D, Wang, J.-H.
Deposit date:2007-07-09
Release date:2007-09-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis of Dscam Isoform Specificity
Nature, 449, 2007
2XOT
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BU of 2xot by Molmil
Crystal structure of neuronal leucine rich repeat protein AMIGO-1
Descriptor: Amphoterin-induced protein 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Kajander, T, Kuja-Panula, J, Rauvala, H, Goldman, A.
Deposit date:2010-08-23
Release date:2011-09-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure and Role of Glycans and Dimerisation in Folding of Neuronal Leucine-Rich Repeat Protein Amigo-1
J.Mol.Biol., 413, 2011
2V9R
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BU of 2v9r by Molmil
First and second Ig domains from human Robo1 (Form 2)
Descriptor: ROUNDABOUT HOMOLOG 1, SULFATE ION
Authors:Morlot, C, Cusack, S, McCarthy, A.A.
Deposit date:2007-08-25
Release date:2007-09-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
2YD9
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BU of 2yd9 by Molmil
Crystal structure of the N-terminal Ig1-3 module of Human Receptor Protein Tyrosine Phosphatase Sigma
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Coles, C.H, Shen, Y, Tenney, A.P, Siebold, C, Sutton, G.C, Lu, W, Gallagher, J.T, Jones, E.Y, Flanagan, J.G, Aricescu, A.R.
Deposit date:2011-03-18
Release date:2011-04-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Proteoglycan-Specific Molecular Switch for Rptp Sigma Clustering and Neuronal Extension.
Science, 332, 2011
2F8V
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BU of 2f8v by Molmil
Structure of full length telethonin in complex with the N-terminus of titin
Descriptor: N2B-Titin Isoform, SULFATE ION, Telethonin
Authors:Pinotsis, N, Petoukhov, M, Lange, S, Svergun, D, Zou, P, Gautel, M, Wilmanns, M.
Deposit date:2005-12-04
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Evidence for a dimeric assembly of two titin/telethonin complexes induced by the telethonin C-terminus.
J.Struct.Biol., 155, 2006
5W21
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BU of 5w21 by Molmil
Crystal Structure of a 1:1:1 FGF23-FGFR1c-aKlotho Ternary Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibroblast growth factor 23, Fibroblast growth factor receptor 1, ...
Authors:Mohammadi, M.
Deposit date:2017-06-05
Release date:2018-01-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:alpha-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling.
Nature, 553, 2018
1VSC
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BU of 1vsc by Molmil
VCAM-1
Descriptor: VASCULAR CELL ADHESION MOLECULE-1
Authors:Wang, J, Stehle, T, Osborn, L.
Deposit date:1995-04-27
Release date:1996-06-20
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of an N-terminal two-domain fragment of vascular cell adhesion molecule 1 (VCAM-1): a cyclic peptide based on the domain 1 C-D loop can inhibit VCAM-1-alpha 4 integrin interaction.
Proc.Natl.Acad.Sci.USA, 92, 1995
8G4L
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BU of 8g4l by Molmil
Cryo-EM structure of the human cardiac myosin filament
Descriptor: Myosin light chain 3, Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, ...
Authors:Dutta, D, Nguyen, V, Padron, R, Craig, R.
Deposit date:2023-02-10
Release date:2023-11-01
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Cryo-EM structure of the human cardiac myosin filament.
Nature, 623, 2023
4PBX
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BU of 4pbx by Molmil
Crystal structure of the six N-terminal domains of human receptor protein tyrosine phosphatase sigma
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase S
Authors:Coles, C.H, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A.W, Nakagawa, T, Craig, A.M, Jones, E.Y, Aricescu, A.R.
Deposit date:2014-04-14
Release date:2014-11-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis.
Nat Commun, 5, 2014
4PBW
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BU of 4pbw by Molmil
Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with TrkC
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NT-3 growth factor receptor, Protein-tyrosine phosphatase CRYPalpha1 isoform
Authors:Coles, C.H, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A.W, Nakagawa, T, Craig, A.M, Jones, E.Y, Aricescu, A.R.
Deposit date:2014-04-14
Release date:2014-11-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis.
Nat Commun, 5, 2014
8S9P
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BU of 8s9p by Molmil
1:1:1 agrin/LRP4/MuSK complex
Descriptor: Agrin, Low-density lipoprotein receptor-related protein 4, Muscle, ...
Authors:Xie, T, Xu, G.J, Liu, Y, Quade, B, Lin, W.C, Bai, X.C.
Deposit date:2023-03-29
Release date:2023-05-17
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
7OL2
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BU of 7ol2 by Molmil
Crystal structure of mouse contactin 1 immunoglobulin domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-1, ...
Authors:Chataigner, L.M.P, Janssen, B.J.C.
Deposit date:2021-05-19
Release date:2022-12-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.89 Å)
Cite:Structural insights into the contactin 1 - neurofascin 155 adhesion complex.
Nat Commun, 13, 2022
7CEG
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BU of 7ceg by Molmil
Crystal structure of the complex between mouse PTP delta and neuroligin-3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform C of Receptor-type tyrosine-protein phosphatase delta, Neuroligin-3
Authors:Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S.
Deposit date:2020-06-23
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Nat Commun, 12, 2021
7OL4
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BU of 7ol4 by Molmil
Mouse contactin-1 neurofascin-155 immunoglobulin domains adhesion complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-1, Neurofascin, ...
Authors:Chataigner, L.M.P, Janssen, B.J.C.
Deposit date:2021-05-19
Release date:2022-12-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4.8 Å)
Cite:Structural insights into the contactin 1 - neurofascin 155 adhesion complex.
Nat Commun, 13, 2022
8Q6T
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BU of 8q6t by Molmil
Helical reconstruction of the relaxed thick filament from FIB milled left ventricular mouse myofibrils
Descriptor: Myosin binding protein C, cardiac, Myosin light chain 3, ...
Authors:Tamborrini, D, Raunser, S.
Deposit date:2023-08-14
Release date:2023-11-01
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Structure of the native myosin filament in the relaxed cardiac sarcomere.
Nature, 623, 2023
4J23
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BU of 4j23 by Molmil
Low resolution crystal structure of the FGFR2D2D3/FGF1/SR128545 complex
Descriptor: Fibroblast growth factor 1, Fibroblast growth factor receptor 2
Authors:Kudlinzki, D, Saxena, K, Sreeramulu, S, Schieborr, U, Dreyer, M, Schreuder, H, Schwalbe, H.
Deposit date:2013-02-04
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.882 Å)
Cite:Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling.
Cancer Cell, 23, 2013
8A1F
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BU of 8a1f by Molmil
Human PTPRK N-terminal domains MAM-Ig-FN1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hay, I.M, Graham, S.C, Sharpe, H.J, Deane, J.E.
Deposit date:2022-06-01
Release date:2023-03-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains.
J.Biol.Chem., 299, 2023
6YGN
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BU of 6ygn by Molmil
Titin kinase and its flanking domains
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Titin
Authors:Fleming, J.R, Franke, B, Bogomolovas, J, Mayans, O.
Deposit date:2020-03-27
Release date:2021-04-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere.
Embo Rep., 22, 2021
8K53
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BU of 8k53 by Molmil
Structure of the Dimeric Human CNTN2 Ig 1-6-FNIII 1-2 Domain in an Asymmetric State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-2, ...
Authors:Zhang, Z.Z.
Deposit date:2023-07-21
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of human CNTN2 immunoglobulin domains 1-6 homo-dimer
To Be Published
7LRG
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BU of 7lrg by Molmil
Filamentous actin decorated with human cardiac myosin binding protein C C2 domain
Descriptor: Actin, alpha cardiac muscle 1, Myosin-binding protein C, ...
Authors:Galkin, V.E.
Deposit date:2021-02-16
Release date:2021-08-11
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Interaction of the C2 Ig-like Domain of Cardiac Myosin Binding Protein-C with F-actin.
J.Mol.Biol., 433, 2021

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