8A1F

Human PTPRK N-terminal domains MAM-Ig-FN1

Summary for 8A1F

Entry DOI	10.2210/pdb8a1f/pdb
Descriptor	Receptor-type tyrosine-protein phosphatase kappa, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	receptor phosphatase, homophilic complex, cell adhesion
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	85612.94
Authors	Hay, I.M.,Graham, S.C.,Sharpe, H.J.,Deane, J.E. (deposition date: 2022-06-01, release date: 2023-03-15, Last modification date: 2024-02-07)
Primary citation	Hay, I.M.,Shamin, M.,Caroe, E.R.,Mohammed, A.S.A.,Svergun, D.I.,Jeffries, C.M.,Graham, S.C.,Sharpe, H.J.,Deane, J.E. Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299:102750-102750, 2023 Cited by PubMed: 36436563 DOI: 10.1016/j.jbc.2022.102750 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation