7NZ4
| Cryo-EM structure of the MukBEF dimer | Descriptor: | 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, Chromosome partition protein MukB, ... | Authors: | Buermann, F, Lowe, J. | Deposit date: | 2021-03-23 | Release date: | 2021-07-07 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (13 Å) | Cite: | Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites. Mol.Cell, 81, 2021
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7YO1
| Cryo-EM structure of RCK1 mutated human Slo1-LRRC26 complex | Descriptor: | CALCIUM ION, Calcium-activated potassium channel subunit alpha-1, Leucine-rich repeat-containing protein 26, ... | Authors: | Yamanouchi, D, Nureki, O. | Deposit date: | 2022-08-01 | Release date: | 2024-03-06 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for dual allosteric gating modulation of Slo1-LRRC channel complex To Be Published
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7YO0
| Cryo-EM structure of human Slo1-LRRC26 complex with Symmetry Expansion | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Calcium-activated potassium channel subunit alpha-1, ... | Authors: | Yamanouchi, D, Nureki, O. | Deposit date: | 2022-08-01 | Release date: | 2024-03-06 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for dual allosteric gating modulation of Slo1-LRRC channel complex To Be Published
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7NYX
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7O31
| Crystal structure of the anti-PAS Fab 1.2 in complex with its epitope peptide and the anti-Kappa VHH domain | Descriptor: | 1,2-ETHANEDIOL, PAS#1 epitope peptide, anti-Kappa VHH domain, ... | Authors: | Schilz, J, Schiefner, A, Skerra, A. | Deposit date: | 2021-04-01 | Release date: | 2021-07-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope. J.Mol.Biol., 433, 2021
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7OGM
| A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation. PNPase-3'ETS(leuZ)-Hfq | Descriptor: | 3'ETS(LeuZ), Polyribonucleotide nucleotidyltransferase, RNA-binding protein Hfq | Authors: | Dendooven, T, Sinha, D, Roesoleva, A, Cameron, T.A, De Lay, N, Luisi, B.F, Bandyra, K. | Deposit date: | 2021-05-06 | Release date: | 2021-07-07 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation. Mol.Cell, 81, 2021
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7NYW
| Cryo-EM structure of the MukBEF-MatP-DNA head module | Descriptor: | 4'-PHOSPHOPANTETHEINE, ADENOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... | Authors: | Buermann, F, Lowe, J. | Deposit date: | 2021-03-23 | Release date: | 2021-07-07 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites. Mol.Cell, 81, 2021
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7O2Z
| Crystal structure of the anti-PAS Fab 2.2 in complex with its epitope peptide | Descriptor: | CHLORIDE ION, P/A#1 epitope peptide, anti-PAS Fab 2.2 chimeric heavy chain, ... | Authors: | Schilz, J, Schiefner, A, Skerra, A. | Deposit date: | 2021-04-01 | Release date: | 2021-07-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope. J.Mol.Biol., 433, 2021
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7ZEZ
| Trimolecular complex Cyp33-RRMdelta alpha : MLL1-PHD3 : H3K4me3 | Descriptor: | Histone H3, Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, MLL cleavage product N320, ... | Authors: | Blatter, M, Allain, F, Meylan, C. | Deposit date: | 2022-03-31 | Release date: | 2022-04-13 | Last modified: | 2023-05-03 | Method: | SOLUTION NMR | Cite: | RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
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7ZG4
| Crystal structure of YTHDF2 with compound YLI_DF_042 | Descriptor: | GLYCEROL, N-methylpyrimidine-2-carboximidamide, SULFATE ION, ... | Authors: | Nai, F, Li, Y, Caflisch, A. | Deposit date: | 2022-04-01 | Release date: | 2022-04-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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7ZKC
| Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum (apo form) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, UDP-glucose-glycoprotein glucosyltransferase-like protein | Authors: | Roversi, P, Zitzmann, N, Bayo, Y, Le Cornu, J.D. | Deposit date: | 2022-04-12 | Release date: | 2022-04-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.769 Å) | Cite: | A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint. Iscience, 26, 2023
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7ZHB
| Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-glucose (conformation 2) | Descriptor: | 1,3-PROPANDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Roversi, P, Zitzmann, N, Bayo, Y, Le Cornu, J.D. | Deposit date: | 2022-04-06 | Release date: | 2022-04-20 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint To Be Published
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7ZPP
| Cryo-EM structure of the MVV CSC intasome at 4.5A resolution | Descriptor: | Integrase, vDNA, non-transferred strand, ... | Authors: | Ballandras-Colas, A, Maskell, D, Pye, V.E, Locke, J, Swuec, S, Kotecha, A, Costa, A, Cherepanov, P. | Deposit date: | 2022-04-28 | Release date: | 2022-05-11 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | A supramolecular assembly mediates lentiviral DNA integration Science, 355, 2017
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7ZGU
| Human NLRP3-deltaPYD hexamer | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, NACHT, LRR and PYD domains-containing protein 3 | Authors: | Raisch, T, Machtens, D.A, Bresch, I.B, Eberhage, J, Prumbaum, D, Reubold, T.F, Raunser, S, Eschenburg, S. | Deposit date: | 2022-04-04 | Release date: | 2022-05-18 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structure of the NEK7-independent NLRP3 inflammasome To Be Published
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7ALO
| Structure of B*27:09/photoRL9 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | Authors: | Loll, B, Lan, H, Freund, C. | Deposit date: | 2020-10-07 | Release date: | 2021-06-16 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Exchange catalysis by tapasin exploits conserved and allele-specific features of MHC-I molecules. Nat Commun, 12, 2021
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7AZW
| Crystal structure of the MIZ1-BTB-domain | Descriptor: | GLYCEROL, Zinc finger and BTB domain-containing protein 17 isoform X1 | Authors: | Orth, B, Sander, B, Diederichs, K, Lorenz, S. | Deposit date: | 2020-11-17 | Release date: | 2021-06-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Identification of an atypical interaction site in the BTB domain of the MYC-interacting zinc-finger protein 1. Structure, 29, 2021
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7AYR
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7AYQ
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7AZX
| Crystal structure of the MIZ1-BTB-domain in complex with a HUWE1-derived peptide | Descriptor: | E3 ubiquitin-protein ligase HUWE1, Zinc finger and BTB domain-containing protein 17 isoform X1 | Authors: | Orth, B, Sander, B, Diederichs, K, Lorenz, S. | Deposit date: | 2020-11-17 | Release date: | 2021-06-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Identification of an atypical interaction site in the BTB domain of the MYC-interacting zinc-finger protein 1. Structure, 29, 2021
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7AKP
| Crystal structure of E. coli RNA helicase HrpA-D305A | Descriptor: | ATP-dependent RNA helicase HrpA | Authors: | Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C. | Deposit date: | 2020-10-01 | Release date: | 2021-06-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility. Proc.Natl.Acad.Sci.USA, 118, 2021
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7ZJC
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7AHU
| Anti-FX Fab of mim8 in complex with human FXa | Descriptor: | Anti-FX Fab of mim8 heavy chain, Anti-FX Fab of mim8 light chain, CALCIUM ION, ... | Authors: | Johansson, E. | Deposit date: | 2020-09-25 | Release date: | 2021-07-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A factor VIIIa-mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice. Blood, 138, 2021
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7ZMV
| Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G5-006 | Descriptor: | ATP-dependent DNA helicase Q5, Gluebody G5-006, SULFATE ION, ... | Authors: | Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. | Deposit date: | 2022-04-19 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published
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7ZMM
| Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G2-001 | Descriptor: | ATP-dependent DNA helicase Q5, Gluebody G2-001, ZINC ION | Authors: | Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. | Deposit date: | 2022-04-19 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published
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7ZLE
| Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP | Descriptor: | 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Roversi, P, Zitzmann, N, Bayo, Y, Le Cornu, J.D. | Deposit date: | 2022-04-14 | Release date: | 2022-06-22 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.823 Å) | Cite: | A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint To Be Published
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