7ZGU
Human NLRP3-deltaPYD hexamer
Summary for 7ZGU
| Entry DOI | 10.2210/pdb7zgu/pdb |
| EMDB information | 14713 |
| Descriptor | NACHT, LRR and PYD domains-containing protein 3, ADENOSINE-5'-DIPHOSPHATE (2 entities in total) |
| Functional Keywords | inflammasome, immunity, nod-like receptor, nacht, lrr, pyd, immune system |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 6 |
| Total formula weight | 633579.46 |
| Authors | Raisch, T.,Machtens, D.A.,Bresch, I.B.,Eberhage, J.,Prumbaum, D.,Reubold, T.F.,Raunser, S.,Eschenburg, S. (deposition date: 2022-04-04, release date: 2022-05-18, Last modification date: 2025-07-02) |
| Primary citation | Raisch, T.,Machtens, D.A.,Bresch, I.B.,Eberhage, J.,Prumbaum, D.,Reubold, T.F.,Raunser, S.,Eschenburg, S. Cryo-EM structure of the NEK7-independent NLRP3 inflammasome To Be Published, |
| Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
Download full validation report






