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7ZGU

Human NLRP3-deltaPYD hexamer

Summary for 7ZGU
Entry DOI10.2210/pdb7zgu/pdb
EMDB information14713
DescriptorNACHT, LRR and PYD domains-containing protein 3, ADENOSINE-5'-DIPHOSPHATE (2 entities in total)
Functional Keywordsinflammasome, immunity, nod-like receptor, nacht, lrr, pyd, immune system
Biological sourceHomo sapiens (human)
Total number of polymer chains6
Total formula weight633579.46
Authors
Raisch, T.,Machtens, D.A.,Bresch, I.B.,Eberhage, J.,Prumbaum, D.,Reubold, T.F.,Raunser, S.,Eschenburg, S. (deposition date: 2022-04-04, release date: 2022-05-18, Last modification date: 2025-07-02)
Primary citationRaisch, T.,Machtens, D.A.,Bresch, I.B.,Eberhage, J.,Prumbaum, D.,Reubold, T.F.,Raunser, S.,Eschenburg, S.
Cryo-EM structure of the NEK7-independent NLRP3 inflammasome
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.4 Å)
Structure validation

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