7ZGU
Human NLRP3-deltaPYD hexamer
Summary for 7ZGU
Entry DOI | 10.2210/pdb7zgu/pdb |
EMDB information | 14713 |
Descriptor | NACHT, LRR and PYD domains-containing protein 3, ADENOSINE-5'-DIPHOSPHATE (2 entities in total) |
Functional Keywords | inflammasome, immunity, nod-like receptor, nacht, lrr, pyd, immune system |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 6 |
Total formula weight | 633579.46 |
Authors | Raisch, T.,Machtens, D.A.,Bresch, I.B.,Eberhage, J.,Prumbaum, D.,Reubold, T.F.,Raunser, S.,Eschenburg, S. (deposition date: 2022-04-04, release date: 2022-05-18, Last modification date: 2024-07-24) |
Primary citation | Raisch, T.,Machtens, D.A.,Bresch, I.B.,Eberhage, J.,Prumbaum, D.,Reubold, T.F.,Raunser, S.,Eschenburg, S. Cryo-EM structure of the NEK7-independent NLRP3 inflammasome To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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