7ZGU

Human NLRP3-deltaPYD hexamer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	NACHT, LRR and PYD domains-containing protein 3	polymer	924	105169.4	6	UniProt (Q96P20) Pfam (PF14484) Pfam (PF05729) Pfam (PF17779) Pfam (PF17776) Pfam (PF13516) In PDB	Homo sapiens (human)	Angiotensin/vasopressin receptor AII/AVP-like,Caterpiller protein 1.1,CLR1.1,Cold-induced autoinflammatory syndrome 1 protein,Cryopyrin,PYRIN-containing APAF1-like protein 1
2	A, B, C, D, E...	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	6	Chemie (ADP)

Sequence modifications

A, B, C, D, E, F: 126 - 1036 (UniProt: Q96P20)

PDB	External Database	Details
Met 125	-	initiating methionine
Gly 1037	-	expression tag
Ser 1038	-	expression tag
Gly 1039	-	expression tag
Gly 1040	-	expression tag
Asp 1041	-	expression tag
Tyr 1042	-	expression tag
Lys 1043	-	expression tag
Asp 1044	-	expression tag
Asp 1045	-	expression tag
Asp 1046	-	expression tag
Asp 1047	-	expression tag
Lys 1048	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	631016.3
Non-Polymers*	Number of molecules	6
	Total formula weight	2563.2
All*	Total formula weight	633579.5

*Water molecules are not included.