7ZGU
Human NLRP3-deltaPYD hexamer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | NACHT, LRR and PYD domains-containing protein 3 | polymer | 924 | 105169.4 | 6 | UniProt (Q96P20) Pfam (PF14484) Pfam (PF05729) Pfam (PF17779) Pfam (PF17776) Pfam (PF13516) | Homo sapiens (human) | Angiotensin/vasopressin receptor AII/AVP-like,Caterpiller protein 1.1,CLR1.1,Cold-induced autoinflammatory syndrome 1 protein,Cryopyrin,PYRIN-containing APAF1-like protein 1 |
| 2 | G, H, I, J, K... (A, B, C, D, E...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 6 | Chemie (ADP) |
Sequence modifications
A, B, C, D, E, F: 126 - 1036 (UniProt: Q96P20)
| PDB | External Database | Details |
|---|---|---|
| Met 125 | - | initiating methionine |
| Gly 1037 | - | expression tag |
| Ser 1038 | - | expression tag |
| Gly 1039 | - | expression tag |
| Gly 1040 | - | expression tag |
| Asp 1041 | - | expression tag |
| Tyr 1042 | - | expression tag |
| Lys 1043 | - | expression tag |
| Asp 1044 | - | expression tag |
| Asp 1045 | - | expression tag |
| Asp 1046 | - | expression tag |
| Asp 1047 | - | expression tag |
| Lys 1048 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 631016.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2563.2 | |
| All* | Total formula weight | 633579.5 |
