7O31

Crystal structure of the anti-PAS Fab 1.2 in complex with its epitope peptide and the anti-Kappa VHH domain

Summary for 7O31

Entry DOI	10.2210/pdb7o31/pdb
Related	7O2Z 7O30 7O31
Descriptor	anti-PAS Fab 1.2 chimeric light chain, anti-PAS Fab 1.2 chimeric heavy chain, anti-Kappa VHH domain, ... (6 entities in total)
Functional Keywords	antibody, disordered protein antigen, pas polypeptide, protein engineering, immune system
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	4
Total formula weight	63947.00
Authors	Schilz, J.,Schiefner, A.,Skerra, A. (deposition date: 2021-04-01, release date: 2021-07-07, Last modification date: 2024-01-31)
Primary citation	Schilz, J.,Binder, U.,Friedrich, L.,Gebauer, M.,Lutz, C.,Schlapschy, M.,Schiefner, A.,Skerra, A. Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope. J.Mol.Biol., 433:167113-167113, 2021 Cited by PubMed: 34161780 DOI: 10.1016/j.jmb.2021.167113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation