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7ZLE

Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP

Summary for 7ZLE
Entry DOI10.2210/pdb7zle/pdb
Related6FSN 7ZHB 7ZKC
DescriptorUDP-glucose-glycoprotein glucosyltransferase-like protein, URIDINE-5'-DIPHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywordsglycoprotein, misfolding, transferase, endoplasmic reticulum. udp, gt24
Biological sourceChaetomium thermophilum
Total number of polymer chains1
Total formula weight36429.15
Authors
Roversi, P.,Zitzmann, N.,Bayo, Y.,Le Cornu, J.D. (deposition date: 2022-04-14, release date: 2022-06-22, Last modification date: 2024-01-31)
Primary citationCaputo, A.T.,Ibba, R.,Le Cornu, J.D.,Darlot, B.,Hensen, M.,Lipp, C.B.,Marciano, G.,Vasiljevic, S.,Roversi, P.,Zitzmann, N.
A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.823 Å)
Structure validation

218853

PDB entries from 2024-04-24

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