2A1A
 
 | | PKR kinase domain-eIF2alpha Complex | | Descriptor: | Eukaryotic translation initiation factor 2 alpha subunit, Interferon-induced, double-stranded RNA-activated protein kinase | | Authors: | Dar, A.C, Dever, T.E, Sicheri, F. | | Deposit date: | 2005-06-19 | | Release date: | 2005-09-27 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Higher-Order Substrate Recognition of eIF2alpha by the RNA-Dependent Protein Kinase PKR.
Cell(Cambridge,Mass.), 122, 2005
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2AHO
 | | Structure of the archaeal initiation factor eIF2 alpha-gamma heterodimer from Sulfolobus solfataricus complexed with GDPNP | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Translation initiation factor 2 alpha subunit, ... | | Authors: | Yatime, L, Mechulam, Y, Blanquet, S, Schmitt, E. | | Deposit date: | 2005-07-28 | | Release date: | 2006-01-31 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Switch of the gamma Subunit in an Archaeal aIF2alphagamma Heterodimer
Structure, 14, 2006
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2B63
 | | Complete RNA Polymerase II-RNA inhibitor complex | | Descriptor: | 31-MER, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ... | | Authors: | Kettenberger, H, Eisenfuehr, A, Brueckner, F, Theis, M, Famulok, M, Cramer, P. | | Deposit date: | 2005-09-30 | | Release date: | 2005-12-06 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs
Nat.Struct.Mol.Biol., 13, 2006
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2A19
 | | PKR kinase domain- eIF2alpha- AMP-PNP complex. | | Descriptor: | Eukaryotic translation initiation factor 2 alpha subunit, Interferon-induced, double-stranded RNA-activated protein kinase, ... | | Authors: | Dar, A.C, Dever, T.E, Sicheri, F. | | Deposit date: | 2005-06-19 | | Release date: | 2005-09-27 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Higher-Order Substrate Recognition of eIF2alpha by the RNA-Dependent Protein Kinase PKR.
Cell(Cambridge,Mass.), 122, 2005
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2B8K
 | | 12-subunit RNA Polymerase II | | Descriptor: | DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ... | | Authors: | Meyer, P.A, Ye, P, Zhang, M, Suh, M.H, Fu, J. | | Deposit date: | 2005-10-07 | | Release date: | 2006-06-20 | | Last modified: | 2012-06-13 | | Method: | X-RAY DIFFRACTION (4.15 Å) | | Cite: | Phasing RNA Polymerase II Using Intrinsically Bound Zn Atoms: An Updated Structural Model.
Structure, 14, 2006
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7OQY
 | | Cryo-EM structure of the cellular negative regulator TFS4 bound to the archaeal RNA polymerase | | Descriptor: | Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... | | Authors: | Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F. | | Deposit date: | 2021-06-04 | | Release date: | 2021-08-25 | | Last modified: | 2021-11-03 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
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7OQ4
 | | Cryo-EM structure of the ATV RNAP Inhibitory Protein (RIP) bound to the DNA-binding channel of the host's RNA polymerase | | Descriptor: | Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... | | Authors: | Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F. | | Deposit date: | 2021-06-02 | | Release date: | 2021-08-25 | | Last modified: | 2021-10-13 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
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7OOP
 | | Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3) | | Descriptor: | DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ... | | Authors: | Kokic, G, Cramer, P. | | Deposit date: | 2021-05-28 | | Release date: | 2021-10-06 | | Last modified: | 2021-10-27 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
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7OPD
 | | Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 5) | | Descriptor: | Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... | | Authors: | Kokic, G, Cramer, P. | | Deposit date: | 2021-05-31 | | Release date: | 2021-10-06 | | Last modified: | 2021-10-27 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
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7OPC
 | | Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 4) | | Descriptor: | Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... | | Authors: | Kokic, G, Cramer, P. | | Deposit date: | 2021-05-31 | | Release date: | 2021-10-13 | | Last modified: | 2021-10-27 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
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7PYK
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA elongation complex in more-swiveled conformation) | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | | Deposit date: | 2021-10-10 | | Release date: | 2022-03-23 | | Last modified: | 2022-10-05 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7PY7
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG elongation complex in more-swiveled conformation) | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | | Deposit date: | 2021-10-09 | | Release date: | 2022-03-23 | | Last modified: | 2022-10-05 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7PY5
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (the consensus NusA-NusG-EC) | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | | Deposit date: | 2021-10-09 | | Release date: | 2022-03-23 | | Last modified: | 2022-10-05 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7PY6
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG elongation complex in less-swiveled conformation) | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | | Deposit date: | 2021-10-09 | | Release date: | 2022-03-23 | | Last modified: | 2022-10-05 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7PY3
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (the consensus NusA-EC) | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | | Deposit date: | 2021-10-08 | | Release date: | 2022-03-23 | | Last modified: | 2022-10-05 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7PYJ
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA elongation complex in less-swiveled conformation) | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | | Deposit date: | 2021-10-10 | | Release date: | 2022-03-23 | | Last modified: | 2022-10-05 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7QGH
 | | Structure of the E. coli disome - collided 70S ribosome | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | Authors: | Kratzat, H, Buschauer, R, Berninghausen, O, Beckmann, R. | | Deposit date: | 2021-12-08 | | Release date: | 2022-03-16 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (4.48 Å) | | Cite: | Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria.
Nature, 603, 2022
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5VVS
 | | RNA pol II elongation complex | | Descriptor: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Lahiri, I, Leschziner, A.E. | | Deposit date: | 2017-05-20 | | Release date: | 2017-11-22 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.4 Å) | | Cite: | Structural basis for the initiation of eukaryotic transcription-coupled DNA repair.
Nature, 551, 2017
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7XSE
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC42) | | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | Deposit date: | 2022-05-13 | | Release date: | 2022-09-07 | | Last modified: | 2022-10-12 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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7XTD
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC58oct) | | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | Deposit date: | 2022-05-16 | | Release date: | 2022-09-07 | | Last modified: | 2022-10-19 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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7XSX
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC49) | | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | Deposit date: | 2022-05-15 | | Release date: | 2022-09-07 | | Last modified: | 2022-10-12 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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7UIF
 | | Mediator-PIC Early (Core B) | | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | Authors: | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | | Deposit date: | 2022-03-29 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
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7XSZ
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC115) | | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | Deposit date: | 2022-05-15 | | Release date: | 2022-09-07 | | Last modified: | 2022-10-12 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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7UIO
 | | Mediator-PIC Early (Composite Model) | | Descriptor: | ALANINE, ASPARTIC ACID, DNA (37-MER), ... | | Authors: | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | | Deposit date: | 2022-03-29 | | Release date: | 2023-03-01 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
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7UI9
 | | Core Mediator-PICearly (Copy A) | | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | Authors: | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | | Deposit date: | 2022-03-28 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
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