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7OPC
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BU of 7opc by Molmil
Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 4)
Descriptor: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ...
Authors:Kokic, G, Cramer, P.
Deposit date:2021-05-31
Release date:2021-10-13
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
2JA7
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BU of 2ja7 by Molmil
CPD lesion containing RNA Polymerase II elongation complex C
Descriptor: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TP*TP*TTP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', ...
Authors:Brueckner, F, Hennecke, U, Carell, T, Cramer, P.
Deposit date:2006-11-23
Release date:2007-02-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Cpd Damage Recognition by Transcribing RNA Polymerase II.
Science, 315, 2007
2JA6
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BU of 2ja6 by Molmil
CPD lesion containing RNA Polymerase II elongation complex B
Descriptor: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TP*TTP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', ...
Authors:Brueckner, F, Hennecke, U, Carell, T, Cramer, P.
Deposit date:2006-11-23
Release date:2007-02-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:CPD damage recognition by transcribing RNA polymerase II.
Science, 315, 2007
2JA5
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BU of 2ja5 by Molmil
CPD lesion containing RNA Polymerase II elongation complex A
Descriptor: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TTP*TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Brueckner, F, Hennecke, U, Carell, T, Cramer, P.
Deposit date:2006-11-23
Release date:2007-02-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Cpd Damage Recognition by Transcribing RNA Polymerase II
Science, 315, 2007
2A1A
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BU of 2a1a by Molmil
PKR kinase domain-eIF2alpha Complex
Descriptor: Eukaryotic translation initiation factor 2 alpha subunit, Interferon-induced, double-stranded RNA-activated protein kinase
Authors:Dar, A.C, Dever, T.E, Sicheri, F.
Deposit date:2005-06-19
Release date:2005-09-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Higher-Order Substrate Recognition of eIF2alpha by the RNA-Dependent Protein Kinase PKR.
Cell(Cambridge,Mass.), 122, 2005
8B3F
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BU of 8b3f by Molmil
Pol II-CSB-CSA-DDB1-ELOF1
Descriptor: DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ...
Authors:Kokic, G, Cramer, P.
Deposit date:2022-09-16
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Pol II-CSB-CSA-DDB1-ELOF1 structure.
To Be Published
8B3D
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BU of 8b3d by Molmil
Structure of the Pol II-TCR-ELOF1 complex.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA damage-binding protein 1, ...
Authors:Kokic, G, Cramer, P.
Deposit date:2022-09-16
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structure of the Pol II-TCR-ELOF1 complex.
To Be Published
8BVW
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BU of 8bvw by Molmil
RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-20
Release date:2023-05-03
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
6QG0
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BU of 6qg0 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 1)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
7PYK
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BU of 7pyk by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA elongation complex in more-swiveled conformation)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhu, C, Guo, X, Weixlbaumer, A.
Deposit date:2021-10-10
Release date:2022-03-23
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
7PY7
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BU of 7py7 by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG elongation complex in more-swiveled conformation)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhu, C, Guo, X, Weixlbaumer, A.
Deposit date:2021-10-09
Release date:2022-03-23
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
7PY5
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BU of 7py5 by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (the consensus NusA-NusG-EC)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhu, C, Guo, X, Weixlbaumer, A.
Deposit date:2021-10-09
Release date:2022-03-23
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
7PY3
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BU of 7py3 by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (the consensus NusA-EC)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhu, C, Guo, X, Weixlbaumer, A.
Deposit date:2021-10-08
Release date:2022-03-23
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
7PY6
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BU of 7py6 by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG elongation complex in less-swiveled conformation)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhu, C, Guo, X, Weixlbaumer, A.
Deposit date:2021-10-09
Release date:2022-03-23
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
7PYJ
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BU of 7pyj by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA elongation complex in less-swiveled conformation)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhu, C, Guo, X, Weixlbaumer, A.
Deposit date:2021-10-10
Release date:2022-03-23
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
5IP7
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BU of 5ip7 by Molmil
Structure of RNA Polymerase II-Tfg1 peptide complex
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P.
Deposit date:2016-03-09
Release date:2016-05-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:Transcription initiation complex structures elucidate DNA opening.
Nature, 533, 2016
2AHO
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BU of 2aho by Molmil
Structure of the archaeal initiation factor eIF2 alpha-gamma heterodimer from Sulfolobus solfataricus complexed with GDPNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Translation initiation factor 2 alpha subunit, ...
Authors:Yatime, L, Mechulam, Y, Blanquet, S, Schmitt, E.
Deposit date:2005-07-28
Release date:2006-01-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Switch of the gamma Subunit in an Archaeal aIF2alphagamma Heterodimer
Structure, 14, 2006
8CEO
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BU of 8ceo by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2023-02-02
Release date:2023-03-08
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
5FYW
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BU of 5fyw by Molmil
Transcription initiation complex structures elucidate DNA opening (OC)
Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
Authors:Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P.
Deposit date:2016-03-10
Release date:2016-05-18
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.35 Å)
Cite:Transcription Initiation Complex Structures Elucidate DNA Opening
Nature, 533, 2016
8BYQ
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BU of 8byq by Molmil
RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-14
Release date:2023-05-03
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
8CAS
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BU of 8cas by Molmil
Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-24
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
6RXZ
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BU of 6rxz by Molmil
Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state b
Descriptor: 35S ribosomal RNA, 40S ribosomal protein S11-like protein, 40S ribosomal protein S13-like protein, ...
Authors:Cheng, J, Kellner, N, Griesel, S, Berninghausen, O, Beckmann, R, Hurt, E.
Deposit date:2019-06-10
Release date:2019-08-14
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Mol.Cell, 75, 2019
8CEN
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BU of 8cen by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Schilbach, S, Cramer, P.
Deposit date:2023-02-02
Release date:2023-03-22
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
1Y1W
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BU of 1y1w by Molmil
Complete RNA Polymerase II elongation complex
Descriptor: 5'-D(*AP*AP*GP*TP*AP*CP*T)-3', 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*AP*T)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ...
Authors:Cramer, P, Kettenberger, H, Armache, K.-J.
Deposit date:2004-11-19
Release date:2005-01-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS
Mol.Cell, 16, 2004
8C6J
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BU of 8c6j by Molmil
Human spliceosomal PM5 C* complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
Authors:Dybkov, O, Kastner, B, Luehrmann, R.
Deposit date:2023-01-12
Release date:2023-07-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins.
Sci Adv, 9, 2023

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