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2GP6	X-ray crystal structure of Mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase II (mtKasB) Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2 Authors: Sridharan, S, Sacchettini, J, TB Structural Genomics Consortium (TBSGC) Deposit date: 2006-04-17 Release date: 2006-07-18 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: X-Ray Crystal Structure of Mycobacterium tuberculosis beta-Ketoacyl Acyl Carrier Protein Synthase II (mtKasB). J.Mol.Biol., 366, 2007
1EK4	BETA-KETOACYL [ACYL CARRIER PROTEIN] SYNTHASE I IN COMPLEX WITH DODECANOIC ACID TO 1.85 RESOLUTION Descriptor: BETA-KETOACYL [ACYL CARRIER PROTEIN] SYNTHASE I, LAURIC ACID Authors: Olsen, J.G, Kadziola, A, Siggaard-Andersen, M, von Wettstein-Knowles, P, Larsen, S. Deposit date: 2000-03-06 Release date: 2001-04-11 Last modified: 2021-11-03 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structures of beta-ketoacyl-acyl carrier protein synthase I complexed with fatty acids elucidate its catalytic machinery. Structure, 9, 2001
2GFX	Structure of E. coli FabF(C163Q) in complex with Platensimycin Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2, PLATENSIMYCIN Authors: Soisson, S.M, Parthasarathy, G. Deposit date: 2006-03-23 Release date: 2006-05-23 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature, 441, 2006
2GFV	Structure of E. coli FabF (KASII) C163Q mutant Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2 Authors: Soisson, S.M, Parthasarathy, G. Deposit date: 2006-03-23 Release date: 2006-05-23 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature, 441, 2006
1J3N	Crystal Structure of 3-oxoacyl-(acyl-carrier protein) Synthase II from Thermus thermophilus HB8 Descriptor: 3-oxoacyl-(acyl-carrier protein) synthase II, CITRIC ACID, MAGNESIUM ION Authors: Bagautdinov, B, Miyano, M, Tahirov, T.H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2003-02-10 Release date: 2003-03-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of 3-oxoacyl-(acyl-carrier protein) synthase II from Thermus thermophilus HB8. Acta Crystallogr.,Sect.F, 64, 2008
4LS5	Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Bacillus subtilis Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2, GLYCEROL, POTASSIUM ION Authors: Trajtenberg, F, Larrieux, N, Buschiazzo, A. Deposit date: 2013-07-22 Release date: 2014-04-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.803 Å) Cite: Structural insights into bacterial resistance to cerulenin. Febs J., 281, 2014
4LS8	Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a covalent complex with cerulenin Descriptor: (3R,7E,10E)-3-hydroxy-4-oxododeca-7,10-dienamide, 1,2-ETHANEDIOL, 3-oxoacyl-[acyl-carrier-protein] synthase 2, ... Authors: Trajtenberg, F, Larrieux, N, Buschiazzo, A. Deposit date: 2013-07-22 Release date: 2014-04-02 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural insights into bacterial resistance to cerulenin. Febs J., 281, 2014
4LS7	Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a non-covalent complex with cerulenin Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2, Cerulenin, GLYCEROL, ... Authors: Trajtenberg, F, Larrieux, N, Buschiazzo, A. Deposit date: 2013-07-22 Release date: 2014-04-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.674 Å) Cite: Structural insights into bacterial resistance to cerulenin. Febs J., 281, 2014
4LS6	Crystal structure of beta-ketoacyl-ACP synthase II (FabF) I108F mutant from Bacillus subtilis Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2, CHLORIDE ION, GLYCEROL, ... Authors: Trajtenberg, F, Larrieux, N, Buschiazzo, A. Deposit date: 2013-07-22 Release date: 2014-04-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Structural insights into bacterial resistance to cerulenin. Febs J., 281, 2014
4NA1	Crystal Structure of the second ketosynthase from the bacillaene polyketide synthase Descriptor: Polyketide synthase PksJ, SULFATE ION Authors: Gay, D.C, Gay, G.R, Keatinge-Clay, A.T. Deposit date: 2013-10-21 Release date: 2014-02-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.95 Å) Cite: A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase. Structure, 22, 2014
4NA2	Crystal Structure of the second ketosynthase from the bacillaene polyketide synthase bound to its natural intermediate Descriptor: Polyketide synthase PksJ Authors: Gay, D.C, Gay, G.R, Keatinge-Clay, A.T. Deposit date: 2013-10-21 Release date: 2014-02-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase. Structure, 22, 2014
4MZ0	Structure of a ketosynthase-acyltransferase di-domain from module CurL of the curacin A polyketide synthase Descriptor: CALCIUM ION, CurL Authors: Whicher, J.R, Smaga, S.S, Smith, J.L. Deposit date: 2013-09-28 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Cyanobacterial polyketide synthase docking domains: a tool for engineering natural product biosynthesis. Chem.Biol., 20, 2013
4NA3	Crystal Structure of the second ketosynthase from the bacillaene polyketide synthase bound to a hexanoyl substrate mimic Descriptor: Polyketide synthase PksJ, SULFATE ION Authors: Gay, D.C, Gay, G.R, Keatinge-Clay, A.T. Deposit date: 2013-10-21 Release date: 2014-02-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.89 Å) Cite: A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase. Structure, 22, 2014
4OPF	Streptomcyes albus JA3453 oxazolomycin ketosynthase domain OzmH KS8 Descriptor: NRPS/PKS Authors: Osipiuk, J, Bigelow, L, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) Deposit date: 2014-02-05 Release date: 2014-02-19 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
2WGE	Crystal structure of KasA of Mycobacterium tuberculosis with bound TLM Descriptor: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, GLYCEROL, ISOPROPYL ALCOHOL, ... Authors: Luckner, S.R, Kisker, C. Deposit date: 2009-04-17 Release date: 2009-07-21 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal Structures of Mycobacterium Tuberculosis Kasa Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin Structure, 17, 2009
2VZ8	Crystal Structure of Mammalian Fatty Acid Synthase Descriptor: FATTY ACID SYNTHASE Authors: Maier, T, Leibundgut, M, Ban, N. Deposit date: 2008-07-31 Release date: 2008-09-09 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.219 Å) Cite: The Crystal Structure of a Mammalian Fatty Acid Synthase. Science, 321, 2008
2WGF	Crystal structure of Mycobacterium tuberculosis C171Q KasA variant Descriptor: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... Authors: Luckner, S.R, Kisker, C. Deposit date: 2009-04-17 Release date: 2009-07-21 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal Structures of Mycobacterium Tuberculosis Kasa Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin Structure, 17, 2009
2VZ9	Crystal Structure of Mammalian Fatty Acid Synthase in complex with NADP Descriptor: FATTY ACID SYNTHASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Maier, T, Leibundgut, M, Ban, N. Deposit date: 2008-07-31 Release date: 2008-09-09 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.3 Å) Cite: The Crystal Structure of a Mammalian Fatty Acid Synthase. Science, 321, 2008
2WGD	Crystal structure of KasA of Mycobacterium tuberculosis Descriptor: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, GLYCEROL, ISOPROPYL ALCOHOL, ... Authors: Luckner, S.R, Kisker, C. Deposit date: 2009-04-17 Release date: 2009-07-21 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Crystal Structures of Mycobacterium Tuberculosis Kasa Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin Structure, 17, 2009
2WGG	Crystal Structure of Mycobacterium tuberculosis C171Q KasA variant with bound TLM Descriptor: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, DI(HYDROXYETHYL)ETHER, NONAETHYLENE GLYCOL, ... Authors: Luckner, S.R, Kisker, C. Deposit date: 2009-04-17 Release date: 2009-07-21 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structures of Mycobacterium Tuberculosis Kasa Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin Structure, 17, 2009
2VKZ	Structure of the cerulenin-inhibited fungal fatty acid synthase type I multienzyme complex Descriptor: (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, FATTY ACID SYNTHASE SUBUNIT ALPHA, ... Authors: Johansson, P, Wiltschi, B, Kumari, P, Kessler, B, Vonrhein, C, Vonck, J, Oesterhelt, D, Grininger, M. Deposit date: 2008-01-07 Release date: 2008-08-12 Last modified: 2017-06-21 Method: X-RAY DIFFRACTION (4 Å) Cite: Inhibition of the Fungal Fatty Acid Synthase Type I Multienzyme Complex. Proc.Natl.Acad.Sci.USA, 105, 2008
2VB9	beta-ketoacyl-ACP synthase I (KAS) from E. coli, apo structure Descriptor: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, CHLORIDE ION Authors: Pappenberger, G, Schulz-Gasch, T, Bailly, J, Hennig, M. Deposit date: 2007-09-06 Release date: 2007-12-25 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structure-Assisted Discovery of an Aminothiazole Derivative as a Lead Molecule for Inhibition of Bacterial Fatty-Acid Synthesis. Acta Crystallogr.,Sect.D, 63, 2007
2VB7	beta-ketoacyl-ACP synthase I (KAS) from E. coli, apo structure after soak in PEG solution Descriptor: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1 Authors: Pappenberger, G, Schulz-Gasch, T, Bailly, J, Hennig, M. Deposit date: 2007-09-06 Release date: 2007-12-25 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structure-Assisted Discovery of an Aminothiazole Derivative as a Lead Molecule for Inhibition of Bacterial Fatty-Acid Synthesis. Acta Crystallogr.,Sect.D, 63, 2007
2VBA	beta-ketoacyl-ACP synthase I (KAS) from E. coli with bound amino- thiazole inhibitor Descriptor: 2-PHENYLAMINO-4-METHYL-5-ACETYL THIAZOLE, 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1 Authors: Pappenberger, G, Schulz-Gasch, T, Bailly, J, Hennig, M. Deposit date: 2007-09-06 Release date: 2007-12-25 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.36 Å) Cite: Structure-Assisted Discovery of an Aminothiazole Derivative as a Lead Molecule for Inhibition of Bacterial Fatty-Acid Synthesis. Acta Crystallogr.,Sect.D, 63, 2007
2UV8	Crystal structure of yeast fatty acid synthase with stalled acyl carrier protein at 3.1 angstrom resolution Descriptor: FATTY ACID SYNTHASE SUBUNIT ALPHA (FAS2), FATTY ACID SYNTHASE SUBUNIT BETA (FAS1), FLAVIN MONONUCLEOTIDE Authors: Leibundgut, M, Jenni, S, Frick, C, Ban, N. Deposit date: 2007-03-09 Release date: 2007-04-17 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural Basis for Substrate Delivery by Acyl Carrier Protein in the Yeast Fatty Acid Synthase Science, 316, 2007

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