2GFV
Structure of E. coli FabF (KASII) C163Q mutant
Summary for 2GFV
Entry DOI | 10.2210/pdb2gfv/pdb |
Related | 2GFW 2GFX 2GFY |
Descriptor | 3-oxoacyl-[acyl-carrier-protein] synthase 2 (2 entities in total) |
Functional Keywords | fabf; kasii; acyl-enzyme intermediate, transferase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 44662.29 |
Authors | Soisson, S.M.,Parthasarathy, G. (deposition date: 2006-03-23, release date: 2006-05-23, Last modification date: 2024-02-14) |
Primary citation | Wang, J.,Soisson, S.M.,Young, K.,Shoop, W.,Kodali, S.,Galgoci, A.,Painter, R.,Parthasarathy, G.,Tang, Y.S.,Cummings, R.,Ha, S.,Dorso, K.,Motyl, M.,Jayasuriya, H.,Ondeyka, J.,Herath, K.,Zhang, C.,Hernandez, L.,Allocco, J.,Basilio, A.,Tormo, J.R.,Genilloud, O.,Vicente, F.,Pelaez, F.,Colwell, L.,Lee, S.H.,Michael, B.,Felcetto, T.,Gill, C.,Silver, L.L.,Hermes, J.D.,Bartizal, K.,Barrett, J.,Schmatz, D.,Becker, J.W.,Cully, D.,Singh, S.B. Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature, 441:358-361, 2006 Cited by PubMed: 16710421DOI: 10.1038/nature04784 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.29 Å) |
Structure validation
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