4LS7
Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a non-covalent complex with cerulenin
Summary for 4LS7
| Entry DOI | 10.2210/pdb4ls7/pdb |
| Related | 4ls5 4ls6 4ls8 |
| Descriptor | 3-oxoacyl-[acyl-carrier-protein] synthase 2, POTASSIUM ION, GLYCEROL, ... (5 entities in total) |
| Functional Keywords | kasii, condensing enzyme, fatty acid elongation, drug target, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Bacillus subtilis subsp. subtilis |
| Total number of polymer chains | 2 |
| Total formula weight | 92189.87 |
| Authors | Trajtenberg, F.,Larrieux, N.,Buschiazzo, A. (deposition date: 2013-07-22, release date: 2014-04-02, Last modification date: 2023-09-20) |
| Primary citation | Trajtenberg, F.,Altabe, S.,Larrieux, N.,Ficarra, F.,de Mendoza, D.,Buschiazzo, A.,Schujman, G.E. Structural insights into bacterial resistance to cerulenin. Febs J., 281:2324-2338, 2014 Cited by PubMed: 24641521DOI: 10.1111/febs.12785 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.674 Å) |
Structure validation
Download full validation report
