4LS7

Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a non-covalent complex with cerulenin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	3-oxoacyl-[acyl-carrier-protein] synthase 2	polymer	426	45609.3	2	UniProt (O34340) Pfam (PF00109) Pfam (PF02801)	Bacillus subtilis subsp. subtilis	3-oxoacyl-[acyl-carrier-protein] synthase II, Beta-ketoacyl-ACP synthase II, KAS II
2	C, D, H, I (A, B)	POTASSIUM ION	non-polymer		39.1	4	Chemie (K)
3	E, G, K, L (A, B)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
4	F, J (A, B)	Cerulenin	non-polymer		223.3	2	Chemie (1X9)
5	M, N (A, B)	water	water		18.0	697	Chemie (HOH)

Sequence modifications

A, B: 0 - 412 (UniProt: O34340)

PDB	External Database	Details
Met -13	-	initiating methionine
Arg -12	-	expression tag
Gly -11	-	expression tag
Ser -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Gly -3	-	expression tag
Ile -2	-	expression tag
Gln -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	91218.6
Non-Polymers*	Number of molecules	10
	Total formula weight	971.3
All*	Total formula weight	92189.9

*Water molecules are not included.