4LS7
Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a non-covalent complex with cerulenin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | polymer | 426 | 45609.3 | 2 | UniProt (O34340) Pfam (PF00109) Pfam (PF02801) | Bacillus subtilis subsp. subtilis | 3-oxoacyl-[acyl-carrier-protein] synthase II, Beta-ketoacyl-ACP synthase II, KAS II |
| 2 | C, D, H, I (A, B) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) PubChem (813) | |||
| 3 | E, G, K, L (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) PubChem (753) | |||
| 4 | F, J (A, B) | Cerulenin | non-polymer | 223.3 | 2 | Chemie (1X9) PubChem (28517) PubChem (272023) PubChem (5352018) PubChem (6335004) PubChem (6475198) PubChem (14037267) PubChem (73947356) PubChem (5282054) PubChem (163016946) PubChem (175128710) PubChem (86308437) PubChem (87490139) PubChem (88352914) PubChem (92246755) PubChem (92436623) PubChem (92436625) PubChem (137320974) PubChem (163016945) PubChem (163016947) | |||
| 5 | M, N (A, B) | water | water | 18.0 | 697 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 412 (UniProt: O34340)
| PDB | External Database | Details |
|---|---|---|
| Met -13 | - | initiating methionine |
| Arg -12 | - | expression tag |
| Gly -11 | - | expression tag |
| Ser -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ile -2 | - | expression tag |
| Gln -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 91218.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 971.3 | |
| All* | Total formula weight | 92189.9 |
