2VKZ
Structure of the cerulenin-inhibited fungal fatty acid synthase type I multienzyme complex
Summary for 2VKZ
Entry DOI | 10.2210/pdb2vkz/pdb |
Related | 2UV8 |
Descriptor | FATTY ACID SYNTHASE SUBUNIT ALPHA, FATTY ACID SYNTHASE SUBUNIT BETA, (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, ... (4 entities in total) |
Functional Keywords | transferase, phosphorylation, phosphopantetheine, fatty acid synthase, multifunctional enzyme, oxidoreductase, lipid synthesis, fas, nad, nadp, lyase, cerulenin, hydrolase, fatty acid biosynthesis |
Biological source | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) More |
Total number of polymer chains | 6 |
Total formula weight | 1310419.27 |
Authors | Johansson, P.,Wiltschi, B.,Kumari, P.,Kessler, B.,Vonrhein, C.,Vonck, J.,Oesterhelt, D.,Grininger, M. (deposition date: 2008-01-07, release date: 2008-08-12, Last modification date: 2017-06-21) |
Primary citation | Johansson, P.,Wiltschi, B.,Kumari, P.,Kessler, B.,Vonrhein, C.,Vonck, J.,Oesterhelt, D.,Grininger, M. Inhibition of the Fungal Fatty Acid Synthase Type I Multienzyme Complex. Proc.Natl.Acad.Sci.USA, 105:12803-, 2008 Cited by PubMed: 18725634DOI: 10.1073/PNAS.0805827105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4 Å) |
Structure validation
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