2WGF

Crystal structure of Mycobacterium tuberculosis C171Q KasA variant

Summary for 2WGF

• Entry DOI: 10.2210/pdb2wgf/pdb
• Related: 2WGD 2WGE 2WGG
• Descriptor: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, SODIUM ION, TETRAETHYLENE GLYCOL, ... (5 entities in total)
• Functional Keywords: beta ketoacyl synthase i, cytoplasm, transferase, acyltransferase, lipid synthesis, fatty acid biosynthesis
• Biological source: MYCOBACTERIUM TUBERCULOSIS
• Cellular location: Cytoplasm (Potential): P63454
• Total number of polymer chains: 8
• Total formula weight: 348729.37

Authors

Luckner, S.R.,Kisker, C. (deposition date: 2009-04-17, release date: 2009-07-21, Last modification date: 2023-12-13)

• Primary citation: Luckner, S.R.,Machutta, C.A.,Tonge, P.J.,Kisker, C.; Crystal Structures of Mycobacterium Tuberculosis Kasa Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin; Structure, 17:1004-, 2009; PubMed: 19604480; DOI: 10.1016/J.STR.2009.04.012

Experimental method

X-RAY DIFFRACTION (2.15 Å)