2WGG
Crystal Structure of Mycobacterium tuberculosis C171Q KasA variant with bound TLM
Summary for 2WGG
Entry DOI | 10.2210/pdb2wgg/pdb |
Related | 2WGD 2WGE 2WGF |
Descriptor | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, THIOLACTOMYCIN, SODIUM ION, ... (6 entities in total) |
Functional Keywords | beta ketoacyl synthase i, cytoplasm, transferase, acyltransferase, lipid synthesis, fatty acid biosynthesis |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Cellular location | Cytoplasm (Potential): P63454 |
Total number of polymer chains | 8 |
Total formula weight | 353004.76 |
Authors | Luckner, S.R.,Kisker, C. (deposition date: 2009-04-17, release date: 2009-07-21, Last modification date: 2023-12-13) |
Primary citation | Luckner, S.R.,Machutta, C.A.,Tonge, P.J.,Kisker, C. Crystal Structures of Mycobacterium Tuberculosis Kasa Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin Structure, 17:1004-, 2009 Cited by PubMed: 19604480DOI: 10.1016/J.STR.2009.04.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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