2WGG
Crystal Structure of Mycobacterium tuberculosis C171Q KasA variant with bound TLM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1 | polymer | 416 | 43385.0 | 8 | UniProt (P63454) Pfam (PF00109) Pfam (PF02801) UniProt (by SIFTS) (P9WQD9) | MYCOBACTERIUM TUBERCULOSIS | BETA KETOACYL SYNTHASE I, KAS 1, BETA-KETOACYL-ACP SYNTHASE 1 |
| 2 | CA, I, IA, KA, N... (F, A, G, H, B...) | THIOLACTOMYCIN | non-polymer | 210.3 | 8 | Chemie (TLM) | |||
| 3 | AA, DA, J, JA, LA... (E, F, A, G, H...) | SODIUM ION | non-polymer | 23.0 | 8 | Chemie (NA) | |||
| 4 | BA, FA, GA, K, M... (E, F, G, A, B...) | NONAETHYLENE GLYCOL | non-polymer | 414.5 | 8 | Chemie (2PE) | |||
| 5 | EA, HA, L, P, Q... (F, G, A, B, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 7 | Chemie (PEG) | |||
| 6 | NA, OA, PA, QA, RA... (A, B, C, D, E...) | water | water | 18.0 | 930 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 416 (UniProt: P63454)
| PDB | External Database | Details |
|---|---|---|
| Gln 171 | Cys 171 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 347079.8 | |
| Non-Polymers* | Number of molecules | 31 |
| Total formula weight | 5925.0 | |
| All* | Total formula weight | 353004.8 |
