8UXQ
 
 | |
6S6B
 | | Type III-B Cmr-beta Cryo-EM structure of the Apo state | | Descriptor: | CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ... | | Authors: | Sofos, N, Montoya, G, Stella, S. | | Deposit date: | 2019-07-02 | | Release date: | 2020-07-08 | | Last modified: | 2020-09-16 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
|
|
1S6P
 | | CRYSTAL STRUCTURE OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R100943 | | Descriptor: | 1-(4-CYANO-PHENYL)-3-[2-(2,6-DICHLORO-PHENYL)-1-IMINO-ETHYL]-THIOUREA, MAGNESIUM ION, POL polyprotein [Contains: Reverse transcriptase] | | Authors: | Das, K, Arnold, E. | | Deposit date: | 2004-01-26 | | Release date: | 2004-05-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants
J.Med.Chem., 47, 2004
|
|
1S9E
 | | CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R129385 | | Descriptor: | 4-[4-AMINO-6-(2,6-DICHLORO-PHENOXY)-[1,3,5]TRIAZIN-2-YLAMINO]-BENZONITRILE, POL polyprotein [Contains: Reverse transcriptase], POL polyprotein [Contains:Reverse transcriptase] | | Authors: | Das, K, Clark Jr, A.D, Ludovici, D.W, Kukla, M.J, Decorte, B, Lewi, P.J, Hughes, S.H, Janssen, P.A, Arnold, E. | | Deposit date: | 2004-02-04 | | Release date: | 2004-05-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants.
J.Med.Chem., 47, 2004
|
|
6E8G
 | |
5XG3
 | | Crystal structure of the ATPgS-engaged Smc head domain with an extended coiled coil bound to the C-terminal domain of ScpA derived from Bacillus subtilis | | Descriptor: | COBALT (II) ION, Chromosome partition protein Smc, MAGNESIUM ION, ... | | Authors: | Shin, H.-C, Lee, H, Oh, B.-H. | | Deposit date: | 2017-04-11 | | Release date: | 2017-06-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure of Full-Length SMC and Rearrangements Required for Chromosome Organization
Mol. Cell, 67, 2017
|
|
1AVQ
 | |
5XG2
 | |
6ZX6
 | |
6ZX7
 | |
1S9G
 | | CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R120394. | | Descriptor: | 4-[4-AMINO-6-(5-CHLORO-1H-INDOL-4-YLMETHYL)-[1,3,5]TRIAZIN-2-YLAMINO]-BENZONITRILE, POL polyprotein [Contains: Reverse transcriptase] | | Authors: | Das, K, Clark Jr, A.D, Ludovici, D.W, Kukla, M.J, Decorte, B, Lewi, P.J, Hughes, S.H, Janssen, P.A, Arnold, E. | | Deposit date: | 2004-02-04 | | Release date: | 2004-05-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants.
J.Med.Chem., 47, 2004
|
|
6S8B
 | | Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 1 | | Descriptor: | CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ... | | Authors: | Sofos, N, Montoya, G, Stella, S. | | Deposit date: | 2019-07-09 | | Release date: | 2020-07-08 | | Last modified: | 2020-09-16 | | Method: | ELECTRON MICROSCOPY (2.41 Å) | | Cite: | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
|
|
8RC4
 | | Structure of Integrator-PP2A complex | | Descriptor: | DSS1, Integrator complex subunit 1, Integrator complex subunit 10, ... | | Authors: | Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. | | Deposit date: | 2023-12-06 | | Release date: | 2024-02-07 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis of Integrator-dependent RNA polymerase II termination.
Nature, 629, 2024
|
|
6S91
 | | Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 2 | | Descriptor: | CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ... | | Authors: | Sofos, N, Montoya, G, Stella, S. | | Deposit date: | 2019-07-11 | | Release date: | 2020-07-08 | | Last modified: | 2020-09-16 | | Method: | ELECTRON MICROSCOPY (2.68 Å) | | Cite: | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
|
|
5Y20
 | |
6SIC
 | | Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA | | Descriptor: | CRISPR-associated RAMP protein, Cmr1 family, Cmr4 family, ... | | Authors: | Sofos, N, Montoya, G, Stella, S. | | Deposit date: | 2019-08-09 | | Release date: | 2020-07-08 | | Last modified: | 2020-09-16 | | Method: | ELECTRON MICROSCOPY (3.52 Å) | | Cite: | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
|
|
6B43
 | | CryoEM structure and atomic model of the Kaposi's sarcoma-associated herpesvirus capsid | | Descriptor: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | | Authors: | Dai, X.H, Gong, D.Y, Sun, R, Zhou, Z.H. | | Deposit date: | 2017-09-25 | | Release date: | 2017-11-08 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structure and mutagenesis reveal essential capsid protein interactions for KSHV replication.
Nature, 553, 2018
|
|
8W1F
 | | Crystal Structure of DPS-like protein PA4880 from Pseudomonas aeruginosa (dodecamer, Mg bound) | | Descriptor: | DPS-LIKE PROTEIN, FE (II) ION, MAGNESIUM ION, ... | | Authors: | Lovell, S, Liu, L, Seibold, S, Battaile, K.P, Rivera, M. | | Deposit date: | 2024-02-15 | | Release date: | 2024-05-29 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Pseudomonas aeruginosa gene PA4880 encodes a Dps-like protein with a Dps fold, bacterioferritin-type ferroxidase centers, and endonuclease activity.
Front Mol Biosci, 11, 2024
|
|
8W1D
 | | CRYSTAL STRUCTURE OF DPS-LIKE PROTEIN PA4880 FROM PSEUDOMONAS AERUGINOSA (DIMERIC FORM) | | Descriptor: | DPS-LIKE PROTEIN, FE (II) ION | | Authors: | Lovell, S, Battaile, K.P, Rivera, M. | | Deposit date: | 2024-02-15 | | Release date: | 2024-05-29 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Pseudomonas aeruginosa gene PA4880 encodes a Dps-like protein with a Dps fold, bacterioferritin-type ferroxidase centers, and endonuclease activity.
Front Mol Biosci, 11, 2024
|
|
8W1E
 | | Crystal Structure of DPS-like protein PA4880 from Pseudomonas aeruginosa (dodecamer) | | Descriptor: | DPS-LIKE PROTEIN, FE (II) ION, SULFATE ION | | Authors: | Lovell, S, Liu, L, Seibold, S, Battaile, K.P, Rivera, M. | | Deposit date: | 2024-02-15 | | Release date: | 2024-05-29 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Pseudomonas aeruginosa gene PA4880 encodes a Dps-like protein with a Dps fold, bacterioferritin-type ferroxidase centers, and endonuclease activity.
Front Mol Biosci, 11, 2024
|
|
6S8E
 | | Cryo-EM structure of the type III-B Cmr-beta complex bound to non-cognate target RNA | | Descriptor: | CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ... | | Authors: | Sofos, N, Montoya, G, Stella, S. | | Deposit date: | 2019-07-09 | | Release date: | 2020-07-08 | | Last modified: | 2020-09-16 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
|
|
3QPH
 | | The three-dimensional structure of TrmB, a global transcriptional regulator of the hyperthermophilic archaeon Pyrococcus furiosus in complex with sucrose | | Descriptor: | ACETATE ION, GLYCEROL, TrmB, ... | | Authors: | Krug, M, Lee, S.-J, Boos, W, Welte, W, Diederichs, K. | | Deposit date: | 2011-02-13 | | Release date: | 2012-05-30 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.992 Å) | | Cite: | The three-dimensional structure of TrmB, a transcriptional regulator of dual function in the hyperthermophilic archaeon Pyrococcus furiosus in complex with sucrose.
Protein Sci., 22, 2013
|
|
7AY0
 | | Crystal structure of truncated USP1-UAF1 | | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 1, WD repeat-containing protein 48, ZINC ION | | Authors: | Arkinson, C, Rennie, M.L, Walden, H. | | Deposit date: | 2020-11-10 | | Release date: | 2021-03-24 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structural basis of FANCD2 deubiquitination by USP1-UAF1.
Nat.Struct.Mol.Biol., 28, 2021
|
|
7AY2
 | | Crystal structure of truncated USP1-UAF1 reacted with ubiquitin-prg | | Descriptor: | Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 1, WD repeat-containing protein 48, ... | | Authors: | Arkinson, C, Rennie, M.L, Walden, H. | | Deposit date: | 2020-11-10 | | Release date: | 2021-03-24 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural basis of FANCD2 deubiquitination by USP1-UAF1.
Nat.Struct.Mol.Biol., 28, 2021
|
|
1AX6
 | | SOLUTION STRUCTURE OF THE [AF]-C8-DG ADDUCT OPPOSITE A-2 DELETION SITE IN THE NARI HOT SPOT SEQUENCE CONTEXT; NMR, 6 STRUCTURES | | Descriptor: | 2-AMINOFLUORENE, DNA DUPLEX D(CTCGGC-[AF]G-CCATC)D(GATGGCCGAG) | | Authors: | Mao, B, Gorin, A.A, Gu, Z, Hingerty, B.E, Broyde, S, Patel, D.J. | | Deposit date: | 1997-10-30 | | Release date: | 1998-07-01 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the aminofluorene-intercalated conformer of the syn [AF]-C8-dG adduct opposite a--2 deletion site in the NarI hot spot sequence context.
Biochemistry, 36, 1997
|
|
