5A3L
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![BU of 5a3l by Molmil](/molmil-images/mine/5a3l) | Structure of Cea1A in complex with N-Acetylglucosamine | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Kock, M, Brueckner, S, Wozniak, N, Veelders, M, Schlereth, J, Moesch, H.-U, Essen, L.-O. | Deposit date: | 2015-06-02 | Release date: | 2016-06-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | High-Affinity Recognition of Non-Reducing Chitinous Ends by the Yeast Adhesin Cea1 To be Published
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5A45
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![BU of 5a45 by Molmil](/molmil-images/mine/5a45) | Structure of Bacteriorhodopsin obtained from 5um crystals by multi crystal data collection | Descriptor: | BACTERIORHODOPSIN, RETINAL | Authors: | Zander, U, Bourenkov, G, Popov, A.N, de Sanctis, D, McCarthy, A.A, Svensson, O, Round, E.S, Gordeliy, V.I, Mueller-Dieckmann, C, Leonard, G.A. | Deposit date: | 2015-06-05 | Release date: | 2015-11-11 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Meshandcollect: An Automated Multi-Crystal Data-Collection Workflow for Synchrotron Macromolecular Crystallography Beamlines. Acta Crystallogr.,Sect.D, 71, 2015
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5AKH
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![BU of 5akh by Molmil](/molmil-images/mine/5akh) | ligand complex structure of soluble epoxide hydrolase | Descriptor: | 4-[5-[3-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]pyridine, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE, ... | Authors: | Oster, L, Tapani, S, Xue, Y, Kack, H. | Deposit date: | 2015-03-03 | Release date: | 2015-05-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
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4CR4
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![BU of 4cr4 by Molmil](/molmil-images/mine/4cr4) | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome | Descriptor: | 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ... | Authors: | Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F. | Deposit date: | 2014-02-25 | Release date: | 2014-04-02 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.8 Å) | Cite: | Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome. Proc.Natl.Acad.Sci.USA, 111, 2014
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5AI0
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![BU of 5ai0 by Molmil](/molmil-images/mine/5ai0) | Ligand complex structure of soluble epoxide hydrolase | Descriptor: | 4-PHENYL-1,2,5-OXADIAZOL-3-AMINE, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DI(HYDROXYETHYL)ETHER, ... | Authors: | Oster, L, Tapani, S, Xue, Y, Kack, H. | Deposit date: | 2015-02-11 | Release date: | 2015-05-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
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4BTS
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![BU of 4bts by Molmil](/molmil-images/mine/4bts) | THE CRYSTAL STRUCTURE OF THE EUKARYOTIC 40S RIBOSOMAL SUBUNIT IN COMPLEX WITH EIF1 AND EIF1A | Descriptor: | 18S ribosomal RNA, 40S RIBOSOMAL PROTEIN RACK1, 40S RIBOSOMAL PROTEIN RPS10E, ... | Authors: | Weisser, M, Voigts-Hoffmann, F, Rabl, J, Leibundgut, M, Ban, N. | Deposit date: | 2013-06-19 | Release date: | 2013-07-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.703 Å) | Cite: | The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A. Nat. Struct. Mol. Biol., 20, 2013
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4C4K
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![BU of 4c4k by Molmil](/molmil-images/mine/4c4k) | Crystal structure of the titin M10-Obscurin Ig domain 1 complex | Descriptor: | 1,2-ETHANEDIOL, OBSCURIN, TITIN | Authors: | Pernigo, S, Fukuzawa, A, Gautel, M, Steiner, R.A. | Deposit date: | 2013-09-05 | Release date: | 2014-09-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Crystal Structure of the Human Titin:Obscurin Complex Reveals a Conserved Yet Specific Muscle M-Band Zipper Module. J.Mol.Biol., 427, 2015
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5A4L
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![BU of 5a4l by Molmil](/molmil-images/mine/5a4l) | DYRK1A IN COMPLEX WITH FLUORO BENZOTHIAZOLE FRAGMENT | Descriptor: | DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION- REGULATED KINASE 1A, N-(5-FLUORANYL-1,3-BENZOTHIAZOL-2-YL)ETHANAMIDE | Authors: | Rothweiler, U. | Deposit date: | 2015-06-10 | Release date: | 2016-06-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Probing the ATP-Binding Pocket of Protein Kinase Dyrk1A with Benzothiazole Fragment Molecules J.Med.Chem., 59, 2016
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7DFX
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![BU of 7dfx by Molmil](/molmil-images/mine/7dfx) | |
6EIY
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![BU of 6eiy by Molmil](/molmil-images/mine/6eiy) | Crystal structure of KDM5B in complex with KDOPZ000034a. | Descriptor: | 1,2-ETHANEDIOL, 2-chloranyl-~{N}-[2-[4-(3-cyano-7-oxidanylidene-6-propan-2-yl-4~{H}-pyrazolo[1,5-a]pyrimidin-5-yl)pyrazol-1-yl]ethyl]ethanamide, DIMETHYL SULFOXIDE, ... | Authors: | Srikannathasan, V, Newman, J.A, Szykowska, A, Wright, M, Ruda, G.F, Vazquez-Rodriguez, S.A, Kupinska, K, Strain-Damerell, C, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A, Bountra, C, Oppermann, U, Huber, K, von Delft, F. | Deposit date: | 2017-09-19 | Release date: | 2018-05-02 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of KDM5B in complex with KDOPZ000034a. to be published
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4CCN
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![BU of 4ccn by Molmil](/molmil-images/mine/4ccn) | 60S ribosomal protein L8 histidine hydroxylase (NO66 L299C/C300S) in complex with Mn(II), N-oxalylglycine (NOG) and 60S ribosomal protein L8 (RPL8 G220C) peptide fragment (complex-2) | Descriptor: | 1,2-ETHANEDIOL, 60S RIBOSOMAL PROTEIN L8, BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66, ... | Authors: | Chowdhury, R, Schofield, C.J. | Deposit date: | 2013-10-23 | Release date: | 2014-05-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510, 2014
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6E8G
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![BU of 6e8g by Molmil](/molmil-images/mine/6e8g) | |
3VQA
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![BU of 3vqa by Molmil](/molmil-images/mine/3vqa) | HIV-1 IN core domain in complex with 1-benzothiophen-6-amine 1,1-dioxide | Descriptor: | 1-benzothiophen-6-amine 1,1-dioxide, CADMIUM ION, POL polyprotein, ... | Authors: | Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J. | Deposit date: | 2012-03-20 | Release date: | 2013-01-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification? J Biomol Screen, 18, 2013
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6EMW
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![BU of 6emw by Molmil](/molmil-images/mine/6emw) | Structure of S.aureus ClpC in complex with MecA | Descriptor: | ATP-dependent Clp protease ATP-binding subunit, ATP-dependent Clp protease ATP-binding subunit ClpC, Adapter protein MecA, ... | Authors: | Carroni, M, Mogk, A, Bukau, B, Franke, K. | Deposit date: | 2017-10-03 | Release date: | 2017-12-27 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (11 Å) | Cite: | Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control. Elife, 6, 2017
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3VXX
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![BU of 3vxx by Molmil](/molmil-images/mine/3vxx) | Crystal structure of methyl CpG binding domain of MBD4 in complex with the 5mCG/5mCG sequence | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*GP*TP*CP*(5CM)P*GP*GP*TP*AP*GP*TP*GP*AP*CP*T)-3'), ... | Authors: | Otani, J, Arita, K, Kato, T, Kinoshita, M, Ariyoshi, M, Shirakawa, M. | Deposit date: | 2012-09-21 | Release date: | 2013-01-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.204 Å) | Cite: | Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4 J.Biol.Chem., 288, 2013
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8EQV
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![BU of 8eqv by Molmil](/molmil-images/mine/8eqv) | Cryo-EM structure of PRC2 in complex with the long isoform of AEBP2 | Descriptor: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, ... | Authors: | Boudes, M, Zhang, Q, Flanigan, S.F, Davidovich, C. | Deposit date: | 2022-10-09 | Release date: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | To be updated To Be Published
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7D8O
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![BU of 7d8o by Molmil](/molmil-images/mine/7d8o) | Crystal structure of E. coli ToxIN type III toxin-antitoxin complex | Descriptor: | Antitoxin RNA, Type III toxin-antitoxin system ToxN/AbiQ family toxin | Authors: | Manikandan, P, Rothweiler, U, Singh, M. | Deposit date: | 2020-10-08 | Release date: | 2022-01-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.097 Å) | Cite: | Identification, functional characterization, assembly and structure of ToxIN type III toxin-antitoxin complex from E. coli. Nucleic Acids Res., 50, 2022
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8FJ5
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![BU of 8fj5 by Molmil](/molmil-images/mine/8fj5) | Structure of the Haloferax volcanii archaeal type IV pilus | Descriptor: | Pilin_N domain-containing protein | Authors: | Wang, F, Kreutzberger, M.A, Baquero, D.P, Krupovic, M, Egelman, E.H. | Deposit date: | 2022-12-19 | Release date: | 2023-06-28 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | The evolution of archaeal flagellar filaments. Proc.Natl.Acad.Sci.USA, 120, 2023
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6EYD
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![BU of 6eyd by Molmil](/molmil-images/mine/6eyd) | Structure of Mycobacterium smegmatis RNA polymerase Sigma-A holoenzyme | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Kouba, T, Barvik, I, Krasny, L. | Deposit date: | 2017-11-11 | Release date: | 2018-12-12 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.22 Å) | Cite: | The Core and Holoenzyme Forms of RNA Polymerase fromMycobacterium smegmatis. J. Bacteriol., 201, 2019
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7DBH
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![BU of 7dbh by Molmil](/molmil-images/mine/7dbh) | The mouse nucleosome structure containing H3mm18 | Descriptor: | DNA (126-MER), Histone H2A type 1-B, Histone H2B type 3-A, ... | Authors: | Hirai, S, Takizawa, Y, Kujirai, T, Kurumizaka, H. | Deposit date: | 2020-10-20 | Release date: | 2022-01-19 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Unusual nucleosome formation and transcriptome influence by the histone H3mm18 variant. Nucleic Acids Res., 50, 2022
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8FZM
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![BU of 8fzm by Molmil](/molmil-images/mine/8fzm) | |
6F6W
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![BU of 6f6w by Molmil](/molmil-images/mine/6f6w) | Structure of Mycobacterium smegmatis RNA polymerase core | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Kouba, T, Barvik, I, Krasny, L. | Deposit date: | 2017-12-06 | Release date: | 2018-12-19 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.81 Å) | Cite: | The Core and Holoenzyme Forms of RNA Polymerase fromMycobacterium smegmatis. J. Bacteriol., 201, 2019
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8FZK
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![BU of 8fzk by Molmil](/molmil-images/mine/8fzk) | |
8FEF
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![BU of 8fef by Molmil](/molmil-images/mine/8fef) | Structure of Mce1 transporter from Mycobacterium smegmatis (Map0) | Descriptor: | ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... | Authors: | Chen, J, Bhabha, G, Ekiert, D.C. | Deposit date: | 2022-12-06 | Release date: | 2023-02-22 | Last modified: | 2023-08-23 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Structure of an endogenous mycobacterial MCE lipid transporter. Nature, 620, 2023
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8FED
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![BU of 8fed by Molmil](/molmil-images/mine/8fed) | Structure of Mce1-LucB complex from Mycobacterium smegmatis (Map1) | Descriptor: | ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... | Authors: | Chen, J, Bhabha, G, Ekiert, D.C. | Deposit date: | 2022-12-06 | Release date: | 2023-02-22 | Last modified: | 2023-08-23 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Structure of an endogenous mycobacterial MCE lipid transporter. Nature, 620, 2023
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