4C4K

Crystal structure of the titin M10-Obscurin Ig domain 1 complex

Summary for 4C4K

• Entry DOI: 10.2210/pdb4c4k/pdb
• Descriptor: OBSCURIN, TITIN, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: transferase, sarcomere, immunoglobulin domain, limb-girdle muscular dystrophy
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Isoform 3: Cytoplasm, myofibril, sarcomere, M line: Q5VST9; Cytoplasm : Q8WZ42
• Total number of polymer chains: 2
• Total formula weight: 22099.72

Authors

Pernigo, S.,Fukuzawa, A.,Gautel, M.,Steiner, R.A. (deposition date: 2013-09-05, release date: 2014-09-24, Last modification date: 2023-12-20)

• Primary citation: Pernigo, S.,Fukuzawa, A.,Pandini, A.,Holt, M.,Kleinjung, J.,Gautel, M.,Steiner, R.A.; The Crystal Structure of the Human Titin:Obscurin Complex Reveals a Conserved Yet Specific Muscle M-Band Zipper Module.; J.Mol.Biol., 427:718-, 2015; PubMed: 25490259; DOI: 10.1016/J.JMB.2014.11.019

Experimental method

X-RAY DIFFRACTION (1.95 Å)