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2CJY
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BU of 2cjy by Molmil
Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis
Descriptor: CASPASE-3, PHQ-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE
Authors:Ganesan, R, Mittl, P.R.E, Jelakovic, S, Grutter, M.G.
Deposit date:2006-04-09
Release date:2006-06-27
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Extended Substrate Recognition in Caspase-3 Revealed by High Resolution X-Ray Structure Analysis
J.Mol.Biol., 359, 2006
4DCP
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BU of 4dcp by Molmil
Crystal Structure of caspase 3, L168F mutant
Descriptor: Caspase Inhibitor AC-DEVD-CHO, Caspase-3 subunit p12, Caspase-3 subunit p17
Authors:Chung, S.J, Kang, H.J, Kim, S.J.
Deposit date:2012-01-18
Release date:2012-12-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspases 3 and 7
Biosci.Rep., 32, 2012
3EDR
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BU of 3edr by Molmil
The crystal structure of caspase-7 in complex with Acetyl-LDESD-CHO
Descriptor: Caspase-7, Inhibitor Ac-ldesd-cho peptide
Authors:Agniswamy, J.
Deposit date:2008-09-03
Release date:2008-10-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural basis for executioner caspase recognition of P5 position in substrates.
Apoptosis, 13, 2008
2CNO
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BU of 2cno by Molmil
Crystal structures of caspase-3 in complex with aza-peptide epoxide inhibitors.
Descriptor: Aza-peptide epoxide, Caspase-3
Authors:Ganesan, R, Jelakovic, S, Campbell, A.J, Li, Z.Z, Asgian, J.L, Powers, J.C, Grutter, M.G.
Deposit date:2006-05-22
Release date:2007-05-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Exploring the S4 and S1 Prime Subsite Specificities in Caspase-3 with Aza-Peptide Epoxide Inhibitors
Biochemistry, 45, 2006
2CNL
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BU of 2cnl by Molmil
Crystal structures of caspase-3 in complex with aza-peptide epoxide inhibitors.
Descriptor: AZA-PEPTIDE EPOXIDE, CASPASE-3 SUBUNIT P12, CASPASE-3 SUBUNIT P17
Authors:Ganesan, R, Jelakovic, S, Campbell, A.J, Li, Z.Z, Asgian, J.L, Grutter, M.G, Powers, J.C.
Deposit date:2006-05-22
Release date:2007-05-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Exploring the S4 and S1 Prime Subsite Specificities in Caspase-3 with Aza-Peptide Epoxide Inhibitors
Biochemistry, 45, 2006
2CNK
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BU of 2cnk by Molmil
Crystal structures of caspase-3 in complex with aza-peptide epoxide inhibitors.
Descriptor: AZA-PEPTIDE EXPOXIDE, CASPASE-3 P12 SUBUNIT, CASPASE-3 P17 SUBUNIT
Authors:Ganesan, R, Jelakovic, S, Campbell, A.J, Li, Z.Z, Asgian, J.L, Powers, J.C, Grutter, M.G.
Deposit date:2006-05-22
Release date:2007-05-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Exploring the S4 and S1 Prime Subsite Specificities in Caspase-3 with Aza-Peptide Epoxide Inhibitors
Biochemistry, 45, 2006
2CDR
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BU of 2cdr by Molmil
Crystal structures of caspase-3 in complex with aza-peptide epoxide inhibitors.
Descriptor: AZA-PEPTIDE EXPOXIDE, CASPASE-3 SUBUNIT P12, CASPASE-3 SUBUNIT P17
Authors:Ganesan, R, Jelakovic, S, Campbell, A.J, Li, Z.Z, Asgian, J.L, Powers, J.C, Gruetter, M.G.
Deposit date:2006-01-27
Release date:2007-03-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Exploring the S4 and S1 Prime Subsite Specificities in Caspase-3 with Aza-Peptide Epoxide Inhibitors.
Biochemistry, 45, 2006
2CNN
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BU of 2cnn by Molmil
Crystal structures of caspase-3 in complex with aza-peptide epoxide inhibitors.
Descriptor: AZA-PEPTIDE EXPOXIDE, Caspase-3
Authors:Ganesan, R, Jelakovic, S, Campbell, A.J, Li, Z.Z, Asgian, J.L, Powers, J.C, Grutter, M.G.
Deposit date:2006-05-22
Release date:2007-05-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Exploring the S4 and S1 Prime Subsite Specificities in Caspase-3 with Aza-Peptide Epoxide Inhibitors
Biochemistry, 45, 2006
3E4C
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BU of 3e4c by Molmil
Procaspase-1 zymogen domain crystal structure
Descriptor: Caspase-1, MAGNESIUM ION
Authors:Elliott, J.M, Rouge, L, Wiesmann, C, Scheer, J.M.
Deposit date:2008-08-11
Release date:2008-12-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of procaspase-1 zymogen domain reveals insight into inflammatory caspase autoactivation
J.Biol.Chem., 284, 2009
4DCO
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BU of 4dco by Molmil
Crystal Structure of caspase 3, L168Y mutant
Descriptor: Caspase Inhibitor AC-DEVD-CHO, Caspase-3 subunit p12, Caspase-3 subunit p17
Authors:Chung, S.J, Kang, H.J, Kim, S.J.
Deposit date:2012-01-18
Release date:2012-12-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspases 3 and 7
Biosci.Rep., 32, 2012
4DCJ
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BU of 4dcj by Molmil
Crystal structure of caspase 3, L168D mutant
Descriptor: Caspase Inhibitor AC-DEVD-CHO, Caspase-3 subunit p12, Caspase-3 subunit p17
Authors:Chung, S.J, Kang, H.J, Kim, S.J.
Deposit date:2012-01-17
Release date:2012-12-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspases 3 and 7
Biosci.Rep., 32, 2012
3EDQ
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BU of 3edq by Molmil
Crystal structure of Caspase-3 with inhibitor AC-LDESD-CHO
Descriptor: AC-LDESD-CHO peptide, Caspase-3
Authors:Fu, G.
Deposit date:2008-09-03
Release date:2008-10-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structural basis for executioner caspase recognition of P5 position in substrates.
Apoptosis, 13, 2008
4EHA
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BU of 4eha by Molmil
Allosteric Modulation of Caspase-3 through Mutagenesis
Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3
Authors:Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C.
Deposit date:2012-04-02
Release date:2012-06-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.696 Å)
Cite:Allosteric modulation of caspase 3 through mutagenesis.
Biosci.Rep., 32, 2012
4EHH
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BU of 4ehh by Molmil
Allosteric Modulation of Caspase-3 through Mutagenesis
Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3
Authors:Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C.
Deposit date:2012-04-02
Release date:2012-06-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Allosteric modulation of caspase 3 through mutagenesis.
Biosci.Rep., 32, 2012
2DKO
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BU of 2dko by Molmil
Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis
Descriptor: Caspase-3, PHQ-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE
Authors:Mittl, P.R.E, Ganesan, R, Jelakovic, S, Grutter, M.G.
Deposit date:2006-04-12
Release date:2006-07-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.06 Å)
Cite:Extended Substrate Recognition in Caspase-3 Revealed by High Resolution X-ray Structure Analysis
J.Mol.Biol., 359, 2006
4EHL
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BU of 4ehl by Molmil
Allosteric Modulation of Caspase-3 through Mutagenesis
Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3
Authors:Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C.
Deposit date:2012-04-02
Release date:2012-06-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Allosteric modulation of caspase 3 through mutagenesis.
Biosci.Rep., 32, 2012
4EHD
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BU of 4ehd by Molmil
Allosteric Modulation of Caspase-3 through Mutagenesis
Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3
Authors:Walters, J, Schipper, J.L, Swartz, P, Mattos, C, Clark, A.C.
Deposit date:2012-04-02
Release date:2012-06-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.581 Å)
Cite:Allosteric modulation of caspase 3 through mutagenesis.
Biosci.Rep., 32, 2012
4EHN
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BU of 4ehn by Molmil
Allosteric Modulation of Caspase-3 through Mutagenesis
Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3
Authors:Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C.
Deposit date:2012-04-02
Release date:2012-06-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Allosteric modulation of caspase 3 through mutagenesis.
Biosci.Rep., 32, 2012
4EHK
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BU of 4ehk by Molmil
Allosteric Modulation of Caspase-3 through Mutagenesis
Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3
Authors:Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C.
Deposit date:2012-04-02
Release date:2012-06-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.668 Å)
Cite:Allosteric modulation of caspase 3 through mutagenesis.
Biosci.Rep., 32, 2012
4EHF
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BU of 4ehf by Molmil
Allosteric Modulation of Caspase-3 through Mutagenesis
Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3
Authors:Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C.
Deposit date:2012-04-02
Release date:2012-06-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.655 Å)
Cite:Allosteric modulation of caspase 3 through mutagenesis.
Biosci.Rep., 32, 2012
4EJF
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BU of 4ejf by Molmil
Allosteric peptides that bind to a caspase zymogen and mediate caspase tetramerization
Descriptor: Caspase-6, PHOSPHATE ION, phage-derived peptide 419
Authors:Murray, J.M.
Deposit date:2012-04-06
Release date:2012-06-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6465 Å)
Cite:Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization.
Nat.Chem.Biol., 8, 2012
4F6P
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BU of 4f6p by Molmil
Crystal structure of the yeast metacaspase Yca1 C276A mutant
Descriptor: 1,1-diphenylethanol, Metacaspase-1
Authors:Wong, A.H, Yan, C.Y, Shi, Y.G.
Deposit date:2012-05-15
Release date:2013-03-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.619 Å)
Cite:Crystal structure of the metacaspase Yca1
To be Published
4FDL
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BU of 4fdl by Molmil
Crystal structure of Caspase-7
Descriptor: Caspase-7
Authors:Kabaleeswaran, V.
Deposit date:2012-05-28
Release date:2012-08-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:A class of allosteric caspase inhibitors identified by high-throughput screening.
Mol.Cell, 47, 2012
4FEA
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BU of 4fea by Molmil
Crystal structure of CASPASE-7 in Complex with allosteric inhibitor
Descriptor: Caspase-7, chloro{methyl hydrogenato(3-)-kappa~2~N,S [pyridin-2-yl(pyridin-2(1H)-ylidene-kappaN)methyl]carbonodithiohydrazonate}copper
Authors:Kabaleeswaran, V.
Deposit date:2012-05-29
Release date:2012-08-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.79 Å)
Cite:A class of allosteric caspase inhibitors identified by high-throughput screening.
Mol.Cell, 47, 2012
4F6O
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BU of 4f6o by Molmil
Crystal structure of the yeast metacaspase Yca1
Descriptor: 1,1-diphenylethanol, Metacaspase-1
Authors:Wong, A.H, Yan, C.Y, Shi, Y.G.
Deposit date:2012-05-15
Release date:2012-07-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.681 Å)
Cite:Crystal structure of the yeast metacaspase Yca1.
J.Biol.Chem., 287, 2012

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